[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593243":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":35,"locations":41,"responsibleParty":117,"collaborators":119,"id":134,"slug":135,"hasResults":136,"nctId":137,"briefTitle":138,"officialTitle":138,"acronym":139,"eligibilityCriteria":140,"healthyVolunteers":136,"sex":141,"minAge":142,"maxAge":34,"enrollmentInfo":143,"targetDuration":34,"studyType":146,"phases":147,"briefSummary":149,"conditions":150,"keywords":156,"overallStatus":94,"whyStopped":34,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":169},{"fullName":5,"class":6},"Uppsala University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Investigational device","EXPERIMENTAL","Will recieve 7 days of treatment with negative pressure wound therapy after closure of emergency surgery incision",[13],"Device: Negative pressure wound therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of care","ACTIVE_COMPARATOR","Will recieve a regular dressing after closure of emergency surgery incision",[19],"Device: Standard postoperative dressing",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Negative pressure wound therapy","Avance Solo Negative Pressure Wound Therapy (NPWT) System is a portable battery powered single use negative pressure system, suitable for use in closed incision and chronic wound indications.\n\nThe system consists of Avance Solo Pump, Avance Solo Canister 50 mL, Avance Solo Border Dressing and Avance Solo Foam.",[9],[27],"Avance Solo",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Standard postoperative dressing","Mepilex Border Post-Op is a self-adhesive absorbent surgical dressing designed for exuding wounds. It is intended for acute wounds, such as surgical wounds, cuts and abrasions.",[15],[33],"Mepilex Border Post-Op",null,[36],{"name":37,"role":38,"phone":39,"phoneExt":34,"email":40},"Erik Osterman, MD PhD","CONTACT","+460186110000","erik.osterman@akademiska.se",[42,59,70,81,92,106],{"facility":43,"status":44,"city":45,"state":34,"zip":34,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Mälar Hospital","NOT_YET_RECRUITING","Eskilstuna","Sweden","SE",{"type":49,"coordinates":50},"Point",[51,52],16.5077,59.36661,{"lat":52,"lon":51},[55,57],{"name":56,"role":38,"phone":34,"phoneExt":34,"email":34},"Carl-Johan Drott, MD PhD",{"name":58,"role":38,"phone":34,"phoneExt":34,"email":34},"Ninos Oussi, MD PhD",{"facility":60,"status":44,"city":61,"state":34,"zip":34,"country":46,"countryCode":47,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Linköping University Hospital","Linköping",{"type":49,"coordinates":63},[64,65],15.62157,58.41086,{"lat":65,"lon":64},[68],{"name":69,"role":38,"phone":34,"phoneExt":34,"email":34},"Marcus Permert Fraser, MD",{"facility":71,"status":44,"city":72,"state":34,"zip":34,"country":46,"countryCode":47,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Mora Hospital","Mora",{"type":49,"coordinates":74},[75,76],14.54316,61.00704,{"lat":76,"lon":75},[79],{"name":80,"role":38,"phone":34,"phoneExt":34,"email":34},"Johanna Österberg, MD PhD",{"facility":82,"status":44,"city":83,"state":34,"zip":34,"country":46,"countryCode":47,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Vrinnevi Hospital","Norrköping",{"type":49,"coordinates":85},[86,87],16.1826,58.59419,{"lat":87,"lon":86},[90],{"name":91,"role":38,"phone":34,"phoneExt":34,"email":34},"Måns Muhrbeck, MD PhD",{"facility":93,"status":94,"city":95,"state":34,"zip":96,"country":46,"countryCode":47,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"Uppsala University Hospital","RECRUITING","Uppsala","75185",{"type":49,"coordinates":98},[99,100],17.63889,59.85882,{"lat":100,"lon":99},[103,104],{"name":37,"role":38,"phone":34,"phoneExt":34,"email":34},{"name":105,"role":38,"phone":34,"phoneExt":34,"email":34},"Fredrik Linder, MD PhD",{"facility":107,"status":44,"city":108,"state":34,"zip":34,"country":46,"countryCode":47,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Västmanlands Hospital Västerås","Västerås",{"type":49,"coordinates":110},[111,112],16.55276,59.61617,{"lat":112,"lon":111},[115],{"name":116,"role":38,"phone":34,"phoneExt":34,"email":34},"Per Holmström, MD",{"type":118,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR",[120,123,125,127,129,131],{"name":121,"class":122},"Uppsala County Council, Sweden","OTHER_GOV",{"name":124,"class":6},"Dalarna County Council, Sweden",{"name":126,"class":6},"Sormland County Council, Sweden",{"name":128,"class":6},"Ostergotland County Council, Sweden",{"name":130,"class":122},"Västmanland County Council, Sweden",{"name":132,"class":133},"Landstingens Ömsesidiga Försäkringsbolag (Löf)","UNKNOWN","100593243","treating-emergency-laparotomy-incisions-with-negative-pressure-wound-therapy-100593243",false,"NCT07003906","Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy","TELIN","Inclusion Criteria:\n\n* ≥18 years old\n* Written informed consent\n* \\>10 cm midline incision with primary skin closure\n* Emergency laparotomy\n\nExclusion Criteria:\n\n* Not able to consent (e.g. dementia, impaired cognitive function, unconscious)\n* Subjects not possible to follow up as assessed by the Investigator\n* Allergy to dressing material\n* Pregnancy or breastfeeding (females of childbearing potential)\n* Previous enrolment in the current study\n* Expected reoperation with 28 days of index laparotomy\n* Emergency laparotomy within 3 months","ALL","18 Years",{"count":144,"type":145},720,"ESTIMATED","INTERVENTIONAL",[148],"NA","The goal of this clinical trial is to investigate Negative Pressure Wound Therapy (NPWT) in adults undergoing emergency laparotomy. The main question it aims to answer is:\n\nDoes NPWT decrease wound complications?\n\nResearchers will compare it against regular dressings to see if NPWT is superior.",[151,152,153,154,155],"Surgical Incision","Wound Dehiscence","Surgical Site Infection","Incisional Hernia","Quality of Life",[157,158,159],"emergency surgery","negative pressure wound therapy","randomised controlled trial","2025-12-18",{"date":162,"type":163},"2025-12-26","ACTUAL",{"date":165,"type":163},"2025-12-16",{"date":167,"type":145},"2035-12",{"name":5,"class":6},6]