[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514024":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":34,"centralContacts":38,"locations":46,"responsibleParty":60,"collaborators":29,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":29,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":29,"enrollmentInfo":72,"targetDuration":29,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":48,"whyStopped":29,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"total glucosides of paeony treatment","ACTIVE_COMPARATOR","Total glucosides of paeony capsules were given 0.6 g once, 3 times a day.",[13],"Drug: total glucosides of paeony treatment",{"label":15,"type":10,"description":16,"interventionNames":17},"photodynamic therapy treatment","Cover the lesion with photosensitizer and fix it. Remove the photosensitizer and treat with laser diode.",[18],"Other: photodynamic therapy treatment",{"label":20,"type":21,"description":22,"interventionNames":23},"glucosides of paeony and photodynamic therapy combined treatment","EXPERIMENTAL","Glucosides of paeony and photodynamic therapy are combined for the treatment",[24],"Other: glucosides of paeony and photodynamic therapy combined treatment",[26,30,32],{"type":27,"name":9,"description":11,"armGroupLabels":28,"otherNames":29},"DRUG",[9],null,{"type":6,"name":15,"description":16,"armGroupLabels":31,"otherNames":29},[15],{"type":6,"name":20,"description":22,"armGroupLabels":33,"otherNames":29},[20],[35],{"name":36,"affiliation":5,"role":37},"Zhihui Zhang","PRINCIPAL_INVESTIGATOR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":29,"email":43},"Zhihui Zhang, Dr.","CONTACT","010-82266125","wisdomzhangzhihui@163.com",{"name":45,"role":41,"phone":29,"phoneExt":29,"email":29},"Lin Zeng",[47],{"facility":5,"status":48,"city":49,"state":29,"zip":29,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Beijing","China","CN",{"type":53,"coordinates":54},"Point",[55,56],116.39723,39.9075,{"lat":56,"lon":55},[59],{"name":45,"role":41,"phone":29,"phoneExt":29,"email":29},{"type":61,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100514024","treatment-of-oral-lichen-planus-with-paeoniflorin-and-photodynamic-therapy-100514024",false,"NCT05973097","Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic Therapy","Clinical Study of Combined Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic Therapy","Inclusion Criteria:\n\n* patients with oral lichen planus\n* male or female patients older than 18 years of age\n* patients willing to participate with signed informed consent.\n\nExclusion Criteria:\n\n* pregnant or lactating\n* had serious systemic diseases of the heart, lung, liver, and kidney, or had tumors\n* were unwilling to participate in the experiment.",true,"ALL","18 Years",{"count":73,"type":74},156,"ESTIMATED","INTERVENTIONAL",[77],"NA","Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa and is considered a precancerous condition. It is characterized by white reticular changes in the oral mucosa, which can progress to erosions and cause pain in severe cases. The pathogenesis of OLP is still unclear, but it is believed to be a T-lymphocyte-mediated autoimmune disease. Currently, only symptomatic treatments are available, and there is no definitive cure.\n\nIn this project, we plan to use TCM differentiation to categorize OLP patients and conduct a randomized controlled clinical trial to demonstrate the enhanced therapeutic effect of paeoniflorin combined with photodynamic therapy for OLP. The implementation of this project will provide new insights into the clinical management of OLP, improve our understanding of the treatment mechanisms, and have important theoretical and clinical implications.",[80],"Oral Lichen Planus",[82,83,84,85],"oral lichen planus","integrated Chinese and Western medicine","total glucosides of paeony","photodynamic therapy","2023-07-25",{"date":88,"type":89},"2023-08-02","ACTUAL",{"date":91,"type":74},"2023-07-30",{"date":93,"type":74},"2028-12-30",{"name":5,"class":6},1]