[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620858":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":10,"responsibleParty":18,"collaborators":10,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":27,"acronym":28,"eligibilityCriteria":29,"healthyVolunteers":24,"sex":30,"minAge":31,"maxAge":10,"enrollmentInfo":32,"targetDuration":35,"studyType":36,"phases":10,"briefSummary":37,"conditions":38,"keywords":40,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":10},{"fullName":5,"class":6},"Ankara City Hospital Bilkent","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"GON_PRF group",null,"This study is a single-center, prospective, single-arm interventional clinical trial designed to evaluate the effectiveness of greater occipital nerve pulsed radiofrequency (GON-PRF) treatment and to identify predictors of treatment response in patients aged 65 years and older with a diagnosis of chronic migraine. Within the scope of the study, patients presenting to the algology clinic who meet the inclusion criteria will undergo ultrasound-guided GON-PRF treatment in accordance with standard clinical practice.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Ulku Sabunccu, Assoc. Prof.","CONTACT","+905337085212","sabuncuulku@gmail.com",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ülkü Sabuncu","Assoc. Prof.","100620858","treatment-response-to-gon-pulsed-radiofrequency-in-elderly-patients-with-chronic-migraine-100620858",false,"NCT07363083","Treatment Response to GON Pulsed Radiofrequency in Elderly Patients With Chronic Migraine","Predictors of Treatment Response to Greater Occipital Nerve Pulsed Radiofrequency in Older Patients With Chronic Migraine","FRAIL-GON","Inclusion Criteria:\n\n* Age 65 years or older\n\nDiagnosis of chronic migraine according to ICHD criteria\n\nPresentation to the algology clinic\n\nEligibility for greater occipital nerve pulsed radiofrequency (GON-PRF) treatment according to the study protocol\n\nAbility to provide written informed consent\n\nExclusion Criteria:\n\n* Acute headache or pain conditions\n\nMalignancy-related headache\n\nSevere cognitive or communication impairment","ALL","65 Years",{"count":33,"type":34},100,"ESTIMATED","6 Months","OBSERVATIONAL","Headache disorders are highly prevalent in older adults, yet their management remains challenging due to comorbidities, polypharmacy, and the paucity of evidence derived from geriatric populations. Most randomized clinical trials exclude elderly patients, underscoring the need for effective and safe non-pharmacological treatment strategies for headache in this age group.\n\nGreater occipital nerve blocks are commonly used in the treatment of migraine and other headache disorders; however, their clinical benefit is often transient. Pulsed radiofrequency (PRF) has been introduced as a minimally invasive technique aimed at prolonging therapeutic effects through neuromodulation without causing structural neural damage. Although greater occipital nerve pulsed radiofrequency (GON-PRF) has demonstrated efficacy in various headache disorders, its effectiveness in patients aged 65 years and older has not been adequately investigated.\n\nThe primary aim of this study is to evaluate the effectiveness of GON-PRF in patients aged ≥65 years with chronic migraine by assessing changes in pain intensity, monthly headache days, and monthly severe headache days. The secondary aim is to identify geriatric predictors of treatment response, including frailty status and the Geriatric Nutritional Risk Index (GNRI), in order to support individualized treatment strategies for older adults.",[39],"Headache, Migraine",[41,42,43],"Migraine Headache","Elderly, Frail","Nerve Blockade","NOT_YET_RECRUITING","2026-02-06",{"date":47,"type":48},"2026-02-10","ACTUAL",{"date":50,"type":34},"2026-03-01",{"date":52,"type":34},"2027-05-01",{"name":5,"class":6}]