[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642446":3},{"organization":4,"armGroups":7,"interventions":78,"overallOfficials":101,"centralContacts":112,"locations":121,"responsibleParty":138,"collaborators":140,"id":144,"slug":145,"hasResults":146,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":150,"eligibilityCriteria":151,"healthyVolunteers":152,"sex":153,"minAge":154,"maxAge":84,"enrollmentInfo":155,"targetDuration":84,"studyType":158,"phases":159,"briefSummary":161,"conditions":162,"keywords":165,"overallStatus":123,"whyStopped":84,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":181},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,18,22,26,30,34,38,42,46,50,54,58,62,66,70,74],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: Exp Condition 1","EXPERIMENTAL","Research participant receives the Constant component + Expert video + Self-persuasion + Narrative storytelling + Motivational interviewing",[13,14,15,16,17],"Behavioral: Expert Video","Behavioral: Self-persuasion","Behavioral: Narrative Storytelling","Behavioral: Motivational Interviewing","Behavioral: Constant Component",{"label":19,"type":10,"description":20,"interventionNames":21},"Experimental: Exp Condition 2","Research participant receives Constant + Expert video + Self-persuasion + Narrative storytelling.",[13,14,15,17],{"label":23,"type":10,"description":24,"interventionNames":25},"Experimental: Exp Condition 3","Research participant receives Constant + Expert video + Self-persuasion + Motivational interviewing",[13,14,16,17],{"label":27,"type":10,"description":28,"interventionNames":29},"Experimental: Exp Condition 4","Research participant receives Constant + Expert video + Self-persuasion",[13,14,17],{"label":31,"type":10,"description":32,"interventionNames":33},"Experimental: Exp Condition 5","Research participant receives Constant + Expert video + Narrative storytelling + Motivational interviewing",[13,15,16,17],{"label":35,"type":10,"description":36,"interventionNames":37},"Experimental: Exp Condition 6","Research participant receives Constant + Expert video + Narrative storytelling",[13,15,17],{"label":39,"type":10,"description":40,"interventionNames":41},"Experimental: Exp Condition 7","Research participant receives Constant + Expert video + Motivational interviewing",[13,16,17],{"label":43,"type":10,"description":44,"interventionNames":45},"Experimental: Exp Condition 8","Research participant receives Constant + Expert video",[13,17],{"label":47,"type":10,"description":48,"interventionNames":49},"Experimental: Exp Condition 9","Research participant receives Constant + Self-persuasion + Narrative storytelling + Motivational interviewing",[14,15,16,17],{"label":51,"type":10,"description":52,"interventionNames":53},"Experimental: Exp Condition 10","Research participant receives Constant + Self-persuasion + Narrative storytelling",[14,15,17],{"label":55,"type":10,"description":56,"interventionNames":57},"Experimental: Exp Condition 11","Research participant receives Constant + Self-persuasion + Motivational interviewing",[14,16,17],{"label":59,"type":10,"description":60,"interventionNames":61},"Experimental: Exp Condition 12","Research participant receives Constant + Self-persuasion",[14,17],{"label":63,"type":10,"description":64,"interventionNames":65},"Experimental: Exp Condition 13","Research participant receives Constant + Narrative storytelling + Motivational interviewing",[15,16,17],{"label":67,"type":10,"description":68,"interventionNames":69},"Experimental: Exp Condition 14","Research participant receives Constant + Narrative storytelling",[15,17],{"label":71,"type":10,"description":72,"interventionNames":73},"Experimental: Exp Condition 15","Research participant receives Constant + Motivational interviewing",[16,17],{"label":75,"type":10,"description":76,"interventionNames":77},"Experimental: Exp Condition 16","Research participant receives the Constant component only",[17],[79,85,89,93,97],{"type":80,"name":81,"description":82,"armGroupLabels":83,"otherNames":84},"BEHAVIORAL","Expert Video","Participants will watch a video featuring Vietnamese healthcare providers. In the video, the providers will endorse vaccine safety and efficacy, dispel common misconceptions or concerns, and use verbal persuasion techniques to recommend HPV vaccination.",[9,19,23,27,31,35,39,43],null,{"type":80,"name":86,"description":87,"armGroupLabels":88,"otherNames":84},"Self-persuasion","Participants will complete an interactive web-based task where they audio record reasons, summarized in their own words, for getting their adolescent the HPV vaccine.",[9,51,55,59,19,23,27,47],{"type":80,"name":90,"description":91,"armGroupLabels":92,"otherNames":84},"Narrative Storytelling","Participants will watch a video featuring U.S. Vietnamese parents. In the video, featured parents will describe stories of their experiences learning about the HPV vaccine as well as motivations to initiate and complete the vaccine series on-time for their adolescents.",[9,51,63,67,19,31,35,47],{"type":80,"name":94,"description":95,"armGroupLabels":96,"otherNames":84},"Motivational Interviewing","Participants will receive 2 calls (phone or Zoom) from a trained U.S. Vietnamese health educator. The health educator will use motivation interviewing (e.g., open-ended questions, acknowledging feelings, affirmations, reflective listening) to increase opportunities for and commitment to HPV vaccination while decreasing barriers (e.g., safety or access concerns).",[9,55,63,71,23,31,39,47],{"type":80,"name":98,"description":99,"armGroupLabels":100,"otherNames":84},"Constant Component","Each participant will receive the constant component through the study website, which includes a vaccine information statement from the CDC with details on HPV vaccine benefits, potential side effects, and recommended vaccination schedule, as well as online information on access and locations for HPV vaccine (e.g., list of Vaccines for Children providers where Medicaid, uninsured, or underinsured adolescents can be vaccinated for free).",[9,51,55,59,63,67,71,75,19,23,27,31,35,39,43,47],[102,105,108,110],{"name":103,"affiliation":5,"role":104},"Milkie Vu, PhD","PRINCIPAL_INVESTIGATOR",{"name":106,"affiliation":5,"role":107},"Namratha Kandula","STUDY_DIRECTOR",{"name":109,"affiliation":5,"role":107},"Siobhan Phillips",{"name":111,"affiliation":5,"role":107},"Juned Siddique",[113,118],{"name":114,"role":115,"phone":116,"phoneExt":84,"email":117},"Milkie Vu","CONTACT","312-503-6592","milkie.vu@northwestern.edu",{"name":119,"role":115,"phone":84,"phoneExt":84,"email":120},"Ninh Nguyen","ninh.nguyen@northwestern.edu",[122],{"facility":5,"status":123,"city":124,"state":125,"zip":126,"country":127,"countryCode":128,"cosmosGeoPoint":129,"geoPoint":134,"contacts":135},"RECRUITING","Chicago","Illinois","60611","United States","US",{"type":130,"coordinates":131},"Point",[132,133],-87.65005,41.85003,{"lat":133,"lon":132},[136,137],{"name":114,"role":115,"phone":116,"phoneExt":84,"email":117},{"name":119,"role":115,"phone":84,"phoneExt":84,"email":120},{"type":104,"investigatorFullName":114,"investigatorTitle":139,"investigatorAffiliation":5,"oldNameTitle":84,"oldOrganization":84},"Assistant Professor",[141],{"name":142,"class":143},"National Cancer Institute (NCI)","NIH","100642446","trial-in-hpv-prevention-for-the-us-vietnamese-community-100642446",false,"NCT07637630","Trial in HPV Prevention for the U.S. Vietnamese Community","Applying the Multiphase Optimization Strategy to Develop and Test a Culturally-Relevant Digital Health Intervention Targeting HPV Vaccination Among U.S. Vietnamese","HERO","Inclusion Criteria:\n\n* Self-identify as U.S. Vietnamese.\n* Are the parent of a youth ages 9-18 who have not initiated the HPV vaccine series. Only one parent per household will be able to participate.\n* Have lived in the U.S. for 12 months or more.\n\nExclusion Criteria:\n\n* Planning to move out of the U.S. within the next 6 months.\n* Not fluent in either spoken and written Vietnamese or spoken and written English.\n* Inability to provide informed consent.",true,"ALL","18 Years",{"count":156,"type":157},96,"ESTIMATED","INTERVENTIONAL",[160],"NA","The purpose of the HERO study is to leverage the Multiphase Optimization Strategy (MOST) framework to conduct a pilot trial testing four different intervention components (expert video, self-persuasion, narrative storytelling, and motivational interviewing) targeting HPV vaccination among U.S. Vietnamese.\n\nPRIMARY AIM To assess the feasibility and acceptability of each of the four digital HERO intervention components in a pilot optimization trial using the MOST framework. Using a highly efficient design, the study team will randomize 96 Vietnamese parents of unvaccinated adolescents to receive 0 to 4 HERO components. The study team will establish the feasibility (reach, retention, adherence) and acceptability (usability, satisfaction, usefulness, cultural relevance) of each component (expert video, self-persuasion, narrative storytelling, and motivational interviewing).\n\nSECONDARY AIM To investigate effects of each component on HPV vaccination outcomes and psychosocial mediators. The study team will examine the effects on HPV vaccination (initiation and intention) and psychosocial mediators.",[163,164],"HPV-related Cancers","HPV Vaccination",[166,167,168,169,170,171],"HPV vaccination","digital health intervention","U.S. Vietnamese","MOST framework","behavioral intervention","adolescent vaccination","2026-06-09",{"date":174,"type":175},"2026-06-11","ACTUAL",{"date":177,"type":175},"2026-05-01",{"date":179,"type":157},"2029-06-30",{"name":5,"class":6},1]