[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512296":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":52,"collaborators":54,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":24,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":24,"overallStatus":36,"whyStopped":24,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Hebrew SeniorLife","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TRAIN AD 2.0","EXPERIMENTAL","Nursing homes randomized to the experimental arm will emply a multicomponent intervention among their providers designed to improve the management of suspected infections in residents with dementia. The components include: a.Orientation sessions for providers, b.On-line case based course for providers, c.Infection management algorithms for providers, d. Guidelines for providers to communicate with proxies, and e. Education booklet about infections in dementia for providers.",[13],"Behavioral: TRAIN AD 2.0",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","ACTIVE_COMPARATOR","Nursing homes randomized to the conrol arm will employ usual care to manage nursing home residents with dementia with suspected infections.",[13],[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","The study intervention is a multi-component training program targeting direct care providers and healthcare proxies for NH residents with moderate to advanced dementia intended to improve the management of urinary tract infections (UTIs) and lower respiratory tract infections (LRIs). The components include: A. Provider Orientation: At NH start-up and q2 months providers will be offered orientations sessions involving two 15-minute presentations, one focused on the background and rationale for the program and one focused on describing the program components. B. A case-based on-line course, \"Infection Management in Moderate to Advanced Dementia,\" C. Posters and pocket cards for providers displaying algorithms guiding appropriate antimicrobial initiation for suspected UTIs and LRIs that integrate patient preferences, and D. Proxies of ALL residents in the facility will be sent a booklet related to infection management for persons with moderate to advanced dementia. .",[9,15],null,[26],{"name":27,"affiliation":5,"role":28},"Susan Mitchell, MD, MPH","PRINCIPAL_INVESTIGATOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":33},"CONTACT","16172813669","smitchell@hsl.harvard.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Boston","Massachusetts","02131","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-71.05977,42.35843,{"lat":46,"lon":45},[49],{"name":50,"role":31,"phone":51,"phoneExt":24,"email":33},"Susan Mitchell","617-281-3669",{"type":53,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[55],{"name":56,"class":6},"Brown University","100512296","trial-to-reduce-antimicrobial-use-in-nursing-home-residents-with-alzheimers-disease-and-other-dementias-20-100512296",false,"NCT05950607","Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0","Trial to Reduce Antimicrobial Use In Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0 (TRAIN-AD 2.0)","TRAIN-AD 2","Inclusion Criteria:\n\n1. Age \\> 60\n2. A diagnosis of dementia (any type)\n3. Cognitive Functional Scale (CFS) \\> 1\n4. NH length of stay \\>90 days\n\nThe CFS score categorizes cognitive impairment status based on data in the electronic health record into: 1. None, 2. Mild, 3. Moderate, and 4. Severe (advanced). For the primary outcome, the analysis will be restricted to residents with a CFS score of 3 or 4.\n\nExclusion Criteria:\n\n1. Less than 60 years of age\n2. Living in nursing home for less than 90 days\n3. Does not have diagnosis of dementia\n4. Does not meet CFS \\>1 score","ALL","60 Years","106 Years",{"count":69,"type":70},750,"ESTIMATED","INTERVENTIONAL",[73],"NA","The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.",[76,77,78],"Dementia","Alzheimer Disease","Infections","2026-01-02",{"date":81,"type":82},"2026-01-06","ACTUAL",{"date":84,"type":82},"2023-11-13",{"date":86,"type":70},"2026-06-30",{"name":5,"class":6},1]