[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100380908":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":32,"centralContacts":36,"locations":46,"responsibleParty":538,"collaborators":541,"id":548,"slug":549,"hasResults":550,"nctId":551,"briefTitle":552,"officialTitle":553,"acronym":10,"eligibilityCriteria":554,"healthyVolunteers":550,"sex":555,"minAge":10,"maxAge":10,"enrollmentInfo":556,"targetDuration":10,"studyType":559,"phases":10,"briefSummary":560,"conditions":561,"keywords":563,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":567,"lastUpdatePostDateStruct":568,"startDateStruct":571,"completionDateStruct":573,"leadSponsor":575,"locationsCount":576},{"fullName":5,"class":6},"University of Alberta","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Kidney transplant biopsies for cause",null,"The study population includes patients with a functioning kidney transplant undergoing a biopsy for clinical indications as standard of care.",[13,14,15],"Diagnostic Test: MMDx","Diagnostic Test: Prospera","Diagnostic Test: HLA antibody",[17,22,28],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"DIAGNOSTIC_TEST","MMDx","Portion of kidney transplant indication biopsy",[9],{"type":18,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Prospera","Transplant patient blood sample",[9],[27],"transplant patient blood sample",{"type":18,"name":29,"description":24,"armGroupLabels":30,"otherNames":31},"HLA antibody",[9],[27],[33],{"name":34,"affiliation":5,"role":35},"Philip F Halloran, MD, PhD","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},"Konrad S Famulski, PhD","CONTACT","1 780 492 1725","konrad@ualberta.ca",{"name":43,"role":39,"phone":44,"phoneExt":10,"email":45},"Robert Polakowski, PhD","1 780 492 5091","polakows@ualberta.ca",[47,67,85,98,117,133,151,167,183,199,216,232,250,271,287,307,326,345,362,374,383,401,415,431,445,461,475,489,495,509,527],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Tampa General Hospital","RECRUITING","Tampa","Florida","33606","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-82.45843,27.94752,{"lat":59,"lon":58},[62,65],{"name":63,"role":39,"phone":10,"phoneExt":10,"email":64},"Natalie Remsen","nremsen@tgh.org",{"name":66,"role":35,"phone":10,"phoneExt":10,"email":10},"Rajendra Baliga, MD",{"facility":68,"status":49,"city":69,"state":70,"zip":71,"country":53,"countryCode":54,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"University of Maryland School of Medicine","Baltimore","Maryland","21201",{"type":56,"coordinates":73},[74,75],-76.61219,39.29038,{"lat":75,"lon":74},[78,81,83],{"name":79,"role":39,"phone":10,"phoneExt":10,"email":80},"Raissa Toure","RToure@som.umaryland.edu",{"name":82,"role":35,"phone":10,"phoneExt":10,"email":10},"Jonathan Bromberg, MD PhD",{"name":84,"role":35,"phone":10,"phoneExt":10,"email":10},"Matt Weir, MD",{"facility":86,"status":49,"city":69,"state":70,"zip":87,"country":53,"countryCode":54,"cosmosGeoPoint":88,"geoPoint":90,"contacts":91},"The Johns Hopkins University, School of Medicine","21205",{"type":56,"coordinates":89},[74,75],{"lat":75,"lon":74},[92,96],{"name":93,"role":39,"phone":94,"phoneExt":10,"email":95},"Darin B Ostrander, PhD","410-614-6702","dostran1@jhmi.edu",{"name":97,"role":35,"phone":10,"phoneExt":10,"email":10},"Daniel C Brennan, MD",{"facility":99,"status":100,"city":101,"state":102,"zip":103,"country":53,"countryCode":54,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"Detroit Medical Center, Harper University Hospital of Wayne State University","NOT_YET_RECRUITING","Detroit","Michigan","48201",{"type":56,"coordinates":105},[106,107],-83.04575,42.33143,{"lat":107,"lon":106},[110,113,114],{"name":111,"role":39,"phone":10,"phoneExt":10,"email":112},"Rajeev Sharma, MD","rasharma@med.wayne.edu",{"name":111,"role":35,"phone":10,"phoneExt":10,"email":10},{"name":115,"role":116,"phone":10,"phoneExt":10,"email":10},"Mareena Zachariah, MD","SUB_INVESTIGATOR",{"facility":118,"status":49,"city":101,"state":102,"zip":119,"country":53,"countryCode":54,"cosmosGeoPoint":120,"geoPoint":122,"contacts":123},"Henry Ford Hospital","48202",{"type":56,"coordinates":121},[106,107],{"lat":107,"lon":106},[124,127,129,131],{"name":125,"role":39,"phone":10,"phoneExt":10,"email":126},"Iman Francis","Ifranci1@hfhs.org",{"name":128,"role":35,"phone":10,"phoneExt":10,"email":10},"Milagros Samaniego-Picota, MD",{"name":130,"role":116,"phone":10,"phoneExt":10,"email":10},"Iman Francis, MD",{"name":132,"role":116,"phone":10,"phoneExt":10,"email":10},"Anita Patel, MD",{"facility":134,"status":49,"city":135,"state":136,"zip":137,"country":53,"countryCode":54,"cosmosGeoPoint":138,"geoPoint":142,"contacts":143},"Barnes-Jewish Hospital, Washington University at St. Louis","St Louis","Missouri","63110",{"type":56,"coordinates":139},[140,141],-90.19789,38.62727,{"lat":141,"lon":140},[144,147,149],{"name":145,"role":39,"phone":10,"phoneExt":10,"email":146},"Andrew Malone","amalone@wustl.edu",{"name":148,"role":35,"phone":10,"phoneExt":10,"email":10},"Andrew Malone, MD PhD",{"name":150,"role":116,"phone":10,"phoneExt":10,"email":10},"Tarek Ahamad, MD",{"facility":152,"status":49,"city":153,"state":154,"zip":155,"country":53,"countryCode":54,"cosmosGeoPoint":156,"geoPoint":160,"contacts":161},"University Hospitals Cleveland Medical Ctr.","Cleveland","Ohio","44106-5048",{"type":56,"coordinates":157},[158,159],-81.69541,41.4995,{"lat":159,"lon":158},[162,165],{"name":163,"role":39,"phone":10,"phoneExt":10,"email":164},"Katherine R Carter","Katherine.carter@uhhospitals.org",{"name":166,"role":35,"phone":10,"phoneExt":10,"email":10},"Jittirat Arksarapuk, MD",{"facility":168,"status":49,"city":153,"state":154,"zip":169,"country":53,"countryCode":54,"cosmosGeoPoint":170,"geoPoint":172,"contacts":173},"Cleveland Clinic","44195",{"type":56,"coordinates":171},[158,159],{"lat":159,"lon":158},[174,177,179,181],{"name":175,"role":39,"phone":10,"phoneExt":10,"email":176},"Debra Camino","caminod@ccf.org",{"name":178,"role":35,"phone":10,"phoneExt":10,"email":10},"Emillio Poggio, MD",{"name":180,"role":35,"phone":10,"phoneExt":10,"email":10},"Richard Fatica, MD",{"name":182,"role":35,"phone":10,"phoneExt":10,"email":10},"Ziad Zaky, MD",{"facility":184,"status":49,"city":185,"state":186,"zip":187,"country":53,"countryCode":54,"cosmosGeoPoint":188,"geoPoint":192,"contacts":193},"Intermountain Transplant Services","Murray","Utah","84107",{"type":56,"coordinates":189},[190,191],-111.88799,40.66689,{"lat":191,"lon":190},[194,197],{"name":195,"role":39,"phone":10,"phoneExt":10,"email":196},"Jake Krong","Jake.Krong@imail.org",{"name":198,"role":35,"phone":10,"phoneExt":10,"email":10},"Sanjiv Anand, MD",{"facility":200,"status":49,"city":201,"state":202,"zip":203,"country":53,"countryCode":54,"cosmosGeoPoint":204,"geoPoint":208,"contacts":209},"Virginia Commonwealth University Medical Center","Richmond","Virginia","23298",{"type":56,"coordinates":205},[206,207],-77.46026,37.55376,{"lat":207,"lon":206},[210,213,214],{"name":211,"role":39,"phone":10,"phoneExt":10,"email":212},"Gaurav Gupta, MD","ggupta@mcvh-vcu.edu",{"name":211,"role":35,"phone":10,"phoneExt":10,"email":10},{"name":215,"role":35,"phone":10,"phoneExt":10,"email":10},"Layla Camal, MD",{"facility":217,"status":49,"city":218,"state":219,"zip":220,"country":53,"countryCode":54,"cosmosGeoPoint":221,"geoPoint":225,"contacts":226},"Division of Nephrology & UW Organ Transplant Center University of Washington","Seattle","Washington","98195",{"type":56,"coordinates":222},[223,224],-122.33207,47.60621,{"lat":224,"lon":223},[227,230],{"name":228,"role":39,"phone":10,"phoneExt":10,"email":229},"Chris Blosser, MD","CBlosser@nephrology.washington.edu",{"name":231,"role":35,"phone":10,"phoneExt":10,"email":10},"Chris Bosser, MD",{"facility":233,"status":49,"city":234,"state":10,"zip":235,"country":236,"countryCode":237,"cosmosGeoPoint":238,"geoPoint":242,"contacts":243},"Department of Nephrology, The Royal Melbourne Hospital 1 South East","Melbourne","VIC 3050","Australia","AU",{"type":56,"coordinates":239},[240,241],144.96332,-37.814,{"lat":241,"lon":240},[244,247,249],{"name":245,"role":39,"phone":10,"phoneExt":10,"email":246},"Peter D Hughes, MD","peter.hughes@mh.org.au",{"name":248,"role":35,"phone":10,"phoneExt":10,"email":10},"Kevin Chow, MD",{"name":245,"role":116,"phone":10,"phoneExt":10,"email":10},{"facility":251,"status":49,"city":252,"state":253,"zip":254,"country":255,"countryCode":256,"cosmosGeoPoint":257,"geoPoint":261,"contacts":262},"University of Alberta, Department of Medicine","Edmonton","Alberta","T6G 2G3","Canada","CA",{"type":56,"coordinates":258},[259,260],-113.46871,53.55014,{"lat":260,"lon":259},[263,266,267,269],{"name":264,"role":39,"phone":10,"phoneExt":10,"email":265},"Soroush Shojai, MD","shojai@ualberta.ca",{"name":264,"role":35,"phone":10,"phoneExt":10,"email":10},{"name":268,"role":116,"phone":10,"phoneExt":10,"email":10},"Sita Gourishankar, MD",{"name":270,"role":116,"phone":10,"phoneExt":10,"email":10},"Majid Sikosana, MD",{"facility":272,"status":49,"city":273,"state":274,"zip":275,"country":255,"countryCode":256,"cosmosGeoPoint":276,"geoPoint":280,"contacts":281},"ST. Paul's Hospital, 6A Providence Building, 1081 Burrard Street","Vancouver","British Columbia","V6Z 1Y6",{"type":56,"coordinates":277},[278,279],-123.11934,49.24966,{"lat":279,"lon":278},[282,285],{"name":283,"role":39,"phone":10,"phoneExt":10,"email":284},"Angela Ogniben","AOgniben@providencehealth.bc.ca",{"name":286,"role":35,"phone":10,"phoneExt":10,"email":10},"John S Gill, MD, MS",{"facility":288,"status":49,"city":289,"state":10,"zip":290,"country":291,"countryCode":292,"cosmosGeoPoint":293,"geoPoint":297,"contacts":298},"University Hospital Merkur Renal Division","Zagreb","1910000","Croatia","HR",{"type":56,"coordinates":294},[295,296],15.97798,45.81444,{"lat":296,"lon":295},[299,302,304,305],{"name":300,"role":39,"phone":10,"phoneExt":10,"email":301},"Zeljka Jurekovic, MD","zeljka.jurekovic@gmail.com",{"name":303,"role":35,"phone":10,"phoneExt":10,"email":10},"Mladen Knotek, MD",{"name":300,"role":116,"phone":10,"phoneExt":10,"email":10},{"name":306,"role":116,"phone":10,"phoneExt":10,"email":10},"Ksenija Vucur, MD",{"facility":308,"status":49,"city":309,"state":10,"zip":310,"country":311,"countryCode":10,"cosmosGeoPoint":312,"geoPoint":316,"contacts":317},"Institute for Clinical and Experimental Medicine (IKEM)","Prague","140 21 Praha 4","Czechia",{"type":56,"coordinates":313},[314,315],14.42076,50.08804,{"lat":315,"lon":314},[318,321,323,324],{"name":319,"role":39,"phone":10,"phoneExt":10,"email":320},"Petra Hruba, MD","hrup@ikem.cz",{"name":322,"role":35,"phone":10,"phoneExt":10,"email":10},"Ondrej Viklicky, MD",{"name":319,"role":116,"phone":10,"phoneExt":10,"email":10},{"name":325,"role":116,"phone":10,"phoneExt":10,"email":10},"Silvie Rajnochová Bloudíčkova",{"facility":327,"status":49,"city":328,"state":10,"zip":329,"country":330,"countryCode":331,"cosmosGeoPoint":332,"geoPoint":336,"contacts":337},"Charite-Medical University of Berlin Department of Nephrology","Berlin","10117","Germany","DE",{"type":56,"coordinates":333},[334,335],13.41053,52.52437,{"lat":335,"lon":334},[338,341,344],{"name":339,"role":39,"phone":10,"phoneExt":10,"email":340},"Klemens Budde, MD","klemens.budde@charite.de",{"name":342,"role":39,"phone":10,"phoneExt":10,"email":343},"Monique Greiner-Pol","monique.greiner-pol@charite.de",{"name":339,"role":35,"phone":10,"phoneExt":10,"email":10},{"facility":346,"status":49,"city":347,"state":10,"zip":348,"country":349,"countryCode":350,"cosmosGeoPoint":351,"geoPoint":355,"contacts":356},"Centre of Nephrology, Vilnius University Hospital Santaros Klinikos","Vilnius","LT-08661","Lithuania","LT",{"type":56,"coordinates":352},[353,354],25.2798,54.68916,{"lat":354,"lon":353},[357,360],{"name":358,"role":39,"phone":10,"phoneExt":10,"email":359},"Alvita Vickiene","alvita.gincaite@gmail.com",{"name":361,"role":35,"phone":10,"phoneExt":10,"email":10},"Marius Miglinas, MD",{"facility":363,"status":364,"city":365,"state":10,"zip":366,"country":367,"countryCode":368,"cosmosGeoPoint":369,"geoPoint":373,"contacts":10},"Department of Nephrology and Transplantation Medical University in Bialystok","COMPLETED","Bialystok","15-540","Poland","PL",{"type":56,"coordinates":370},[371,372],23.16433,53.13333,{"lat":372,"lon":371},{"facility":375,"status":364,"city":376,"state":10,"zip":377,"country":367,"countryCode":368,"cosmosGeoPoint":378,"geoPoint":382,"contacts":10},"University Hospital nr1 Bydgoszcz, Klinika Transplantologii","Bydgoszcz","85-094",{"type":56,"coordinates":379},[380,381],18.00762,53.1235,{"lat":381,"lon":380},{"facility":384,"status":49,"city":385,"state":10,"zip":386,"country":367,"countryCode":368,"cosmosGeoPoint":387,"geoPoint":391,"contacts":392},"Medical University of Gdańsk Klinika Nefrologii Transplantologii i Chorób Wewnętrznych","Gdansk","80-259",{"type":56,"coordinates":388},[389,390],18.64912,54.35227,{"lat":390,"lon":389},[393,396,398,400],{"name":394,"role":39,"phone":10,"phoneExt":10,"email":395},"Andrzej Chamienia, MD","chamien@gumed.edu.pl",{"name":397,"role":35,"phone":10,"phoneExt":10,"email":10},"Alicja Dębska-Ślizień, MD",{"name":399,"role":116,"phone":10,"phoneExt":10,"email":10},"Joanna Konopa, MD",{"name":394,"role":116,"phone":10,"phoneExt":10,"email":10},{"facility":402,"status":49,"city":403,"state":10,"zip":404,"country":367,"countryCode":368,"cosmosGeoPoint":405,"geoPoint":409,"contacts":410},"Medical University of Silesia","Katowice","40-027",{"type":56,"coordinates":406},[407,408],19.02173,50.2597,{"lat":408,"lon":407},[411,414],{"name":412,"role":39,"phone":10,"phoneExt":10,"email":413},"Grzegorz Piecha, MD","g.piecha@outlook.com",{"name":412,"role":35,"phone":10,"phoneExt":10,"email":10},{"facility":416,"status":49,"city":417,"state":10,"zip":418,"country":367,"countryCode":368,"cosmosGeoPoint":419,"geoPoint":423,"contacts":424},"Department of Transplantation and General Surgery, Wojewodzki Hospital","Poznan","60-479",{"type":56,"coordinates":420},[421,422],16.92993,52.40692,{"lat":422,"lon":421},[425,428,429],{"name":426,"role":39,"phone":10,"phoneExt":10,"email":427},"Maciej Glyda, MD","glydam@wp.pl",{"name":426,"role":35,"phone":10,"phoneExt":10,"email":10},{"name":430,"role":116,"phone":10,"phoneExt":10,"email":10},"Katarzyna Smykal-Jankowiak, MD",{"facility":432,"status":49,"city":433,"state":10,"zip":434,"country":367,"countryCode":368,"cosmosGeoPoint":435,"geoPoint":439,"contacts":440},"Department of Nephrology, Transplantation and Internal Medicine, University Hospital n.2","Szczecin","70-111",{"type":56,"coordinates":436},[437,438],14.55302,53.42894,{"lat":438,"lon":437},[441,444],{"name":442,"role":39,"phone":10,"phoneExt":10,"email":443},"Leszek Domański, MD","domanle@pum.edu.pl",{"name":442,"role":35,"phone":10,"phoneExt":10,"email":10},{"facility":446,"status":49,"city":433,"state":10,"zip":447,"country":367,"countryCode":368,"cosmosGeoPoint":448,"geoPoint":450,"contacts":451},"Pomeranian Medical University, Samodzielny Publiczny Woj. Szpital Zespolony, Oddzial Nefrologii i Transplantacji Nerek","71-455",{"type":56,"coordinates":449},[437,438],{"lat":438,"lon":437},[452,455,457,459],{"name":453,"role":39,"phone":10,"phoneExt":10,"email":454},"Marek Myślak, MD Phd","marek.myslak@pum.edu.pl",{"name":456,"role":35,"phone":10,"phoneExt":10,"email":10},"Marek Myślak, MD PhD",{"name":458,"role":116,"phone":10,"phoneExt":10,"email":10},"Joanna Mazurkiewicz, MD",{"name":460,"role":116,"phone":10,"phoneExt":10,"email":10},"Marta Gryczman, MD",{"facility":462,"status":49,"city":463,"state":10,"zip":464,"country":367,"countryCode":368,"cosmosGeoPoint":465,"geoPoint":469,"contacts":470},"Medical University of Warsaw, Department of Transplantation Medicine, Nephrology and Internal Diseases","Warsaw","02-006",{"type":56,"coordinates":466},[467,468],21.01178,52.22977,{"lat":468,"lon":467},[471,474],{"name":472,"role":39,"phone":10,"phoneExt":10,"email":473},"Magdalena Durlik, MD","magdalena.durlik@wum.edu.pl",{"name":472,"role":35,"phone":10,"phoneExt":10,"email":10},{"facility":476,"status":49,"city":463,"state":10,"zip":464,"country":367,"countryCode":368,"cosmosGeoPoint":477,"geoPoint":479,"contacts":480},"Transplant Medicine & Nephrology Clinic, Medical University of Warsaw",{"type":56,"coordinates":478},[467,468],{"lat":468,"lon":467},[481,484,485,487],{"name":482,"role":39,"phone":10,"phoneExt":10,"email":483},"Agnieszka Perkowska-Ptasińska, MD PhD","aggape@poczta.onet.pl",{"name":482,"role":35,"phone":10,"phoneExt":10,"email":10},{"name":486,"role":116,"phone":10,"phoneExt":10,"email":10},"Dominika Dęborska-Materkowska, MD",{"name":488,"role":116,"phone":10,"phoneExt":10,"email":10},"Michał Ciszek, MD",{"facility":490,"status":364,"city":463,"state":10,"zip":491,"country":367,"countryCode":368,"cosmosGeoPoint":492,"geoPoint":494,"contacts":10},"The Children's Memorial Health Institute, Department of Nephrology, Kidney Transplantation and Hypertension","04-730",{"type":56,"coordinates":493},[467,468],{"lat":468,"lon":467},{"facility":496,"status":49,"city":497,"state":10,"zip":498,"country":367,"countryCode":368,"cosmosGeoPoint":499,"geoPoint":503,"contacts":504},"Wroclaw Medical University, Department of Nephrology and Transplantation Medicine","Wroclaw","50-556",{"type":56,"coordinates":500},[501,502],17.03006,51.10286,{"lat":502,"lon":501},[505,508],{"name":506,"role":39,"phone":10,"phoneExt":10,"email":507},"Mirosław Banasik, MD","m.banasik@interia.pl",{"name":506,"role":35,"phone":10,"phoneExt":10,"email":10},{"facility":510,"status":49,"city":511,"state":10,"zip":512,"country":513,"countryCode":514,"cosmosGeoPoint":515,"geoPoint":519,"contacts":520},"Department of Nephrology, University Medical Centre","Ljubljana","21000","Slovenia","SI",{"type":56,"coordinates":516},[517,518],14.50513,46.05108,{"lat":518,"lon":517},[521,524,526],{"name":522,"role":39,"phone":10,"phoneExt":10,"email":523},"Nika Kojc, MD","nika.kojc@mf.uni-lj.si",{"name":525,"role":35,"phone":10,"phoneExt":10,"email":10},"Miha Arnol, MD",{"name":522,"role":116,"phone":10,"phoneExt":10,"email":10},{"facility":528,"status":364,"city":529,"state":10,"zip":530,"country":531,"countryCode":532,"cosmosGeoPoint":533,"geoPoint":537,"contacts":10},"University Hospital Zurich","Zurich","8091","Switzerland","CH",{"type":56,"coordinates":534},[535,536],8.55,47.36667,{"lat":536,"lon":535},{"type":35,"investigatorFullName":539,"investigatorTitle":540,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Philip Halloran","Distinguished Professor",[542,545],{"name":543,"class":544},"Natera, Inc.","INDUSTRY",{"name":546,"class":547},"One Lambda","UNKNOWN","100380908","trifecta-kidney-cfdna-mmdx-study-100380908",false,"NCT04239703","Trifecta-Kidney cfDNA-MMDx Study","Trifecta-Kidney cfDNA-MMDx Study: Comparing the DD-cfDNA Test to MMDx Microarray Test, Central HLA Antibody Test, and Histology.","Inclusion Criteria:\n\n* All kidney transplant recipients undergoing a kidney biopsy for clinical indications, as determined by their physician or surgeon, will be eligible to enroll in the study.\n\nExclusion Criteria:\n\n* Patients will be excluded from the study if they decline participation or are unable to give informed consent or multiple organ recipients.","ALL",{"count":557,"type":558},300,"ESTIMATED","OBSERVATIONAL","Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood, and the Molecular Microscope® (MMDx) Diagnostic System results in indication biopsies.",[562],"Kidney Transplant Rejection",[564,565,566],"donor derived cell-free DNA","blood","kidney biopsy","2026-06-01",{"date":569,"type":570},"2026-06-02","ACTUAL",{"date":572,"type":570},"2019-12-01",{"date":574,"type":558},"2029-12",{"name":5,"class":6},31]