[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624399":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":29,"centralContacts":48,"locations":54,"responsibleParty":73,"collaborators":29,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":29,"eligibilityCriteria":83,"healthyVolunteers":79,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":29,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":99,"overallStatus":105,"whyStopped":29,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"The First Affiliated Hospital of Guangzhou Medical University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Tubeless Strategy Group","EXPERIMENTAL","Participants in this arm receive the tubeless strategy:\n\n* Anesthesia: Laryngeal mask airway with spontaneous ventilation (non-intubated).\n* Drainage: No chest tube placement after surgery\n* Goal: To enhance recovery by minimizing invasive procedures.",[13,14,15],"Device: Laryngeal Mask Airway","Drug: Thoracic Paravertebral Block with Local Anesthetic","Procedure: Non-intubated Anesthesia",{"label":17,"type":18,"description":19,"interventionNames":20},"Traditional Strategy Group","ACTIVE_COMPARATOR","Participants in this arm receive the conventional standard care:\n\n* Anesthesia: Double-lumen endotracheal intubation with mechanical ventilation.\n* Drainage: Routine chest tube drainage with water-seal suction postoperatively.\n* Follows current clinical guidelines for thoracoscopic sublobar resection.",[21,22],"Device: Double-lumen Endotracheal Tube","Device: Chest Tube Drainage",[24,30,35,40,44],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","Laryngeal Mask Airway","Airway management using a laryngeal mask airway with spontaneous ventilation during thoracoscopic surgery.",[9],null,{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":29},"DRUG","Thoracic Paravertebral Block with Local Anesthetic","Thoracic paravertebral block using local anesthetic (e.g., ropivacaine) for intraoperative and postoperative analgesia.",[9],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":29},"PROCEDURE","Non-intubated Anesthesia","General anesthesia with spontaneous ventilation without endotracheal intubation.",[9],{"type":25,"name":41,"description":42,"armGroupLabels":43,"otherNames":29},"Double-lumen Endotracheal Tube","Double-lumen endotracheal intubation for one-lung ventilation under general anesthesia.",[17],{"type":25,"name":45,"description":46,"armGroupLabels":47,"otherNames":29},"Chest Tube Drainage","Routine placement of a chest tube (18-22 Fr) with water-seal drainage postoperatively.",[17],[49],{"name":50,"role":51,"phone":52,"phoneExt":29,"email":53},"Jianxing He, Ph.D","CONTACT","86+020-83062807","drjianxing.he@gmail.com",[55],{"facility":56,"status":29,"city":57,"state":58,"zip":59,"country":58,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"The First Affiliated Hospital of GZMU","Guangzhou","China","510120","CN",{"type":62,"coordinates":63},"Point",[64,65],113.25,23.11667,{"lat":65,"lon":64},[68,71],{"name":69,"role":51,"phone":52,"phoneExt":29,"email":70},"hengrui liang","liang_hengrui@163.com",{"name":72,"role":51,"phone":29,"phoneExt":29,"email":70},"liang",{"type":74,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Jianxing He","Professor of Thoracic Surgery","100624399","tubeless-strategy-for-enhanced-recovery-after-sublobar-resection-100624399",false,"NCT07409129","Tubeless Strategy for Enhanced Recovery After Sublobar Resection","Tubeless Strategy Within an Enhanced Recovery After Surgery (ERAS) Protocol for Thoracoscopic Sublobar Resection: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 75 years.\n* Scheduled for uniportal or multiportal video-assisted thoracoscopic surgery (VATS) for sublobar resection (wedge or segmentectomy).\n* Presence of peripheral lung nodules ≤ 2 cm in diameter and ≤ 2 cm from the pleura, confirmed by CT scan.\n* Ability to understand and provide written informed consent.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n\nExclusion Criteria:\n\n* Severe pleural adhesions or fibrosis that would preclude non-intubated anesthesia or tubeless approach.\n* Severe cardiopulmonary dysfunction: FEV1 \\\u003C 50% predicted, DLCO \\\u003C 60% predicted, heart failure (NYHA class III-IV), or unstable angina.\n* Pregnancy or lactation (confirmed by urine test if applicable).\n* Inability to tolerate one-lung ventilation due to anatomical or physiological reasons.\n* History of ipsilateral thoracic surgery.\n* Active pulmonary infection, uncontrolled diabetes, or other comorbidities that increase surgical risk.\n* Participation in another interventional trial within 30 days.","ALL","18 Years","75 Years",{"count":88,"type":89},138,"ESTIMATED","INTERVENTIONAL",[92],"NA","This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a \"tubeless\" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic sublobar resection (wedge or segment resection) for small lung nodules.\n\nParticipants will be randomly assigned to one of two groups:\n\n* The experimental group will receive the \"tubeless\" strategy, which includes non-endotracheal intubation anesthesia (using a laryngeal mask) and no routine chest tube drainage after surgery.\n* The control group will receive the traditional strategy, which includes double-lumen endotracheal intubation anesthesia and routine chest tube drainage.\n\nThe main goal is to compare the rate of achieving high-quality fast-track recovery at 24 hours after surgery between the two groups. This study will provide evidence on whether the tubeless approach can help patients recover faster and more comfortably without compromising safety.",[95,96,97,98],"Pulmonary Nodules","Early Stage Lung Cancer (I and II)","Thoracoscopic Surgery","Sublobar Resection",[100,37,101,102,103,104],"Tubeless Surgery","Enhanced Recovery After Surgery","Sublobar resection","Wedge Resection","Segmentectomy","NOT_YET_RECRUITING","2026-02-06",{"date":108,"type":109},"2026-02-13","ACTUAL",{"date":111,"type":89},"2026-02-01",{"date":113,"type":89},"2026-09-01",{"name":5,"class":6},1]