[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100490907":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":54,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":26,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":26,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Korea University Guro Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","ACTIVE_COMPARATOR","Continuous channel: normal saline 100ml, 2ml\u002Fh (fixed rate) Selector \\& Bolus channel: fentanyl 20mcg\u002Fkg (Total 50ml with normal saline), bolus 1ml\u002F10min lock-out",[13],"Drug: Control",{"label":15,"type":16,"description":17,"interventionNames":18},"Dexmedetomidine group","EXPERIMENTAL","Continuous channel: dexmedetomidine 10mcg\u002Fkg (Total 100ml with normal saline), 2ml\u002Fh (fixed rate) Selector \\& Bolus channel: fentanyl 20mcg\u002Fkg (Total 50ml with normal saline), bolus 1ml\u002F10min lock-out",[19],"Drug: Dexmedetomidine",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexmedetomidine","Dexmedetomidine 0.2mcg\u002Fkg\u002Fhr (2ml\u002Fhr) administration via continuous channel in the experimental group",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Control","Normal saline 2ml\u002Fhr administration via continuous channel in the experimental group",[9],[32],{"name":33,"affiliation":5,"role":34},"Seok Kyeong Oh, M.D., Ph.D","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","82-2-2626-3237","nanprayboy@korea.ac.kr",[41],{"facility":5,"status":42,"city":43,"state":26,"zip":26,"country":44,"countryCode":26,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Seoul","South Korea",{"type":46,"coordinates":47},"Point",[48,49],126.9784,37.566,{"lat":49,"lon":48},[52],{"name":53,"role":37,"phone":26,"phoneExt":26,"email":26},"Seok Kyeong Oh, MD, PhD",{"type":34,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Seok Kyeong Oh","Associate Professor","100490907","two-channel-iv-pca-with-dexmedetomidine-100490907",false,"NCT05672225","Two-channel IV-PCA With Dexmedetomidine","Effectiveness of Two-channel Intravenous Patient-controlled Analgesia With Dexmedetomidine on Postoperative Opioid Consumption After Major Laparoscopic Abdominal Surgery","Inclusion Criteria:\n\n* Patients who was scheduled for laparoscopic major abdominal surgery (Gastrectomy, Hepatectomy, Colectomy, Pancreatectomy) under general anesthesia\n* Aged ≥ 20 years old\n\nExclusion Criteria:\n\n* Body mass index ≥35 kg\u002Fm2\n* American Society of Anesthesiologists physical status \\> 3\n* Severe cardiovascular disorder\n* Severe liver or renal dysfunction\n* Preoperative dyspnea\n* Contraindication to dexmedetomidine (preoperative severe bradycardia (Heart rate \\\u003C50), atrioventricular block, allergy to dexmedetomidine)\n* Preoperative use of opioid, anticonvulsant, antidepressant","ALL","20 Years",{"count":67,"type":68},110,"ESTIMATED","INTERVENTIONAL",[71],"NA","Dexmedetomidine was administered in the 'selector' channel and fentanyl in the 'basic \\& bolus' channel of dual channel intravenous patient-controlled analgesia (IV-PCA) and the amount of opioid consumption was compared. In addition, intensity of pain, postoperative nausea\u002Fvomiting, and postoperative delirium was evaluated.",[74,23],"Analgesia, Patient-Controlled","2025-01-02",{"date":77,"type":78},"2025-01-03","ACTUAL",{"date":80,"type":78},"2023-02-07",{"date":82,"type":68},"2025-12-31",{"name":5,"class":6},1]