[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497622":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":99,"collaborators":101,"id":107,"slug":108,"hasResults":109,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":109,"sex":114,"minAge":115,"maxAge":116,"enrollmentInfo":117,"targetDuration":10,"studyType":120,"phases":10,"briefSummary":121,"conditions":122,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"Istituto Auxologico Italiano","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"T2D",null,"patients with Type2 diabetes (T2D)",[13],"Diagnostic Test: 1mg DST",{"label":15,"type":10,"description":16,"interventionNames":17},"obese without T2D","obese patients without Type 2 diabetes (T2D)",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","1mg DST","measurement of cortisol levels after 1 mg of dexamethasone (DST) at 11 pm",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Valentina Morelli, PhD","CONTACT","02619112547","v.morelli@auxologico.it",[31,46,57,71,85],{"facility":5,"status":32,"city":33,"state":10,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Milan","20135","Italy","IT",{"type":38,"coordinates":39},"Point",[40,41],9.18951,45.46427,{"lat":41,"lon":40},[44],{"name":45,"role":27,"phone":28,"phoneExt":10,"email":29},"Valentina Morelli",{"facility":47,"status":32,"city":33,"state":10,"zip":48,"country":35,"countryCode":36,"cosmosGeoPoint":49,"geoPoint":51,"contacts":52},"Niguarda Hospital","20162",{"type":38,"coordinates":50},[40,41],{"lat":41,"lon":40},[53],{"name":54,"role":27,"phone":55,"phoneExt":10,"email":56},"Iacopo Chiodini, Prof","+39026444.3376","iacopo.chiodini@ospedaleniguarda.it",{"facility":58,"status":32,"city":59,"state":10,"zip":60,"country":35,"countryCode":36,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Campus Bio-Medico University","Roma","00128",{"type":38,"coordinates":62},[63,64],11.10642,44.99364,{"lat":64,"lon":63},[67],{"name":68,"role":27,"phone":69,"phoneExt":10,"email":70},"Nicola Napoli, Prof","(+39) 06. 22541 697","n.napoli@policlinicocampus.it",{"facility":72,"status":32,"city":73,"state":10,"zip":74,"country":35,"countryCode":36,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"University of Siena","Siena","53100",{"type":38,"coordinates":76},[77,78],11.33064,43.31822,{"lat":78,"lon":77},[81],{"name":82,"role":27,"phone":83,"phoneExt":10,"email":84},"Luigi Gennari, Prof","+39 0577585364","gennari@unisi.it",{"facility":86,"status":32,"city":87,"state":10,"zip":88,"country":35,"countryCode":36,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Azienda Ospedaliero Universitaria, Santa Maria della Misericordia di Udine","Udine","33100",{"type":38,"coordinates":90},[91,92],13.23715,46.0693,{"lat":92,"lon":91},[95],{"name":96,"role":27,"phone":97,"phoneExt":10,"email":98},"Fabio Vescini, Prof","(+39) 0432 552540","endocrinologia@asufc.sanita.fvg.it",{"type":100,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[102,103,104,105],{"name":72,"class":6},{"name":47,"class":6},{"name":58,"class":6},{"name":106,"class":6},"Azienda Ospedaliero Universitaria, Santa Maria della Misericordia di Udine, Italy","100497622","type-2-diabetes-obesity-and-cortisol-excess-100497622",false,"NCT05759637","Type 2 Diabetes, Obesity and Cortisol Excess","DOCOR","Inclusion Criteria:\n\npatients with T2D and Obesity\n\nExclusion Criteria:\n\n* pregnancy\u002Fbreast feeding,\n* sleep apnea,\n* prepuberal onset of hypertension, hormonal hypersecreting adrenal mass,\n* symptoms of hypercortisolism;\n* already known secondary hypertension;\n* conditions associated with increased hypothalamic-pituitary-adrenal (HPA) axis activity, -severe autoimmune\u002Frheumatologic and hematologic diseases, alcoholism, kidney disease (glomerular filtration rate \\\u003C60)\n* drugs influencing the HPA axis activity. For inclusion in Group 2 the presence of T2D will be an exclusion criteria","ALL","18 Years","75 Years",{"count":118,"type":119},3200,"ESTIMATED","OBSERVATIONAL","The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with the HidHyCo presence and the HidHyCo prevalence in an adequate sample of obese patients without T2D and the clinical characteristics more frequently associated with the HidHyCo presence.",[123,124,125],"Diabetes Mellitus, Type 2","Obesity","Cortisol; Hypersecretion","2025-03-19",{"date":128,"type":129},"2025-03-24","ACTUAL",{"date":131,"type":129},"2022-05-06",{"date":133,"type":119},"2025-12-06",{"name":5,"class":6},5]