[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571467":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":33,"responsibleParty":52,"collaborators":55,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":20,"enrollmentInfo":70,"targetDuration":20,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":20,"overallStatus":36,"whyStopped":20,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Erasmus Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Study group","EXPERIMENTAL","Subjects will receive the EndoSign test prior to their scheduled clinically indicated upper endoscopy by an expert endoscopist, per routine standard of care. Additional biopsies will be taken and 10cc of blood will be collected from the cannula used for sedation. Subjects will also receive three questionnaires regarding baseline characteristics, gastrointestinal symptoms and acceptability.",[13],"Device: EndoSign",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","EndoSign","The EndoSign cell collection device is a non-endoscopic capsule sponge device used to collect pan-esophageal samples.\n\nThe Endosign procedure consists of an expandable, spherical mesh, which is attached to a string and contained within a soluble capsule. Seven minutes after swallowing (once the capsule has dissolved), the spherical mesh, which measures around 3cm in diameter is retrieved by pulling on the string. Upon retrieval the capsule-sponge scrapes against the surface of the top of the stomach and esophagus and collects epithelial cells. The capsule-sponge sample is then placed into a preservative fluid and the specimen is processed for molecular tests.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Judith Honing, MSc, PhD","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Anne-Elise C de Groen, MSc","CONTACT","003110 703 16 93","a.degroen@erasmusmc.nl",{"name":23,"role":28,"phone":29,"phoneExt":20,"email":32},"j.honing@erasmusmc.nl",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Erasmus Medisch Centrum","RECRUITING","Rotterdam","South Holland","1315 GD","Netherlands","NL",{"type":43,"coordinates":44},"Point",[45,46],4.47917,51.9225,{"lat":46,"lon":45},[49],{"name":50,"role":28,"phone":51,"phoneExt":20,"email":30},"Anne-Elise C de Groen, MSc in Medicine","+31 6 29 56 33 36",{"type":24,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Judith Honing","Principal Investigator",[56,59],{"name":57,"class":58},"Cyted Health Inc","INDUSTRY",{"name":60,"class":6},"University of Cambridge","100571467","ultralong-segment-barretts-esophagus-towards-a-capsule-sponge-surveillance-strategy-100571467",false,"NCT06720636","Ultralong-segment Barrett's Esophagus: Towards a Capsule-sponge Surveillance Strategy","ULSBE","Inclusion Criteria:\n\n* Any participant 18 years and above, with ultralong-segment Barrett's esophagus and clinically fit for an endoscopy\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Individuals with a diagnosis of an oro-pharynx, esophageal or gastro-esophageal tumor (T2 staging and above), or symptoms of dysphagia\n* Esophageal varices or stricture requiring dilatation of the esophagus\n* Individuals who have had a cerebrovascular event \\\u003C 6 months prior where their swallowing has been affected\n* Patients who have had previous treatments such as Photodynamic therapy (PDT), Radiofrequency ablation (RFA) or Argon Plasma Coagulation (APC) for dysplastic Barrett's esophagus\n* Participants who are unable to provide informed consent\n* Participants under age 18 years","ALL","18 Years",{"count":71,"type":72},137,"ESTIMATED","INTERVENTIONAL",[75],"NA","The purpose of this study is to evaluate the Endosign capsule sponge test as a novel surveillance method in patients with an ultralong-segment Barrett's esophagus.",[78],"Barrett Esophagus","2025-08-06",{"date":81,"type":82},"2025-08-12","ACTUAL",{"date":84,"type":82},"2025-02-03",{"date":86,"type":72},"2027-09",{"name":5,"class":6},1]