[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586262":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":24,"centralContacts":35,"locations":41,"responsibleParty":57,"collaborators":24,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":24,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":24,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":24,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"National Taiwan University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"MBUS group","EXPERIMENTAL","ultrasonication-mediated microbubbles dressing (day 1,3,5) + piroxicam gel (day 2,4,6,7)",[13],"Procedure: ultrasonication-mediated microbubbles dressing",{"label":15,"type":16,"description":17,"interventionNames":18},"US group","SHAM_COMPARATOR","ultrasonication using pure gel (day 1,3,5) + piroxicam gel (day 2,4,6,7)",[19],"Procedure: ultrasonication using pure gel",{"label":21,"type":22,"description":23,"interventionNames":24},"Control group","NO_INTERVENTION","piroxicam gel alone (day 1-7)",null,[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":24},"PROCEDURE","ultrasonication-mediated microbubbles dressing","The microbubble suspension is diluted with normal saline to a concentration of 2x10\\^7 bubbles\u002FmL, applied to a gauze cloth, and covered on the joint skin surface. The joint is ultrasonicated for 3 minutes using an ultrasonic implanter (KUM-2000, NEO-TEC, Taipei, Taiwan), and then piroxicam gel is applied. The parameter values for ultrasonication are duty cycle 0.5, Tempo 10, intensity 70%, and time 3 min. This treatment is performed on day 1, 3, and 5.",[9],{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":24},"ultrasonication using pure gel","The joint is ultrasonicated for 3 minutes using an ultrasonic implanter (KUM-2000, NEO-TEC, Taipei, Taiwan) with pure gel, and then piroxicam gel is applied. The parameter values for ultrasonication are duty cycle 0.5, Tempo 10, intensity 70%, and time 3 min. This treatment is performed on day 1, 3, and 5.",[15],[36],{"name":37,"role":38,"phone":39,"phoneExt":24,"email":40},"Kuo-Lung Lai","CONTACT","886-4-23592525 ext 3354","kllaichiayi@vghtc.gov.tw",[42],{"facility":43,"status":44,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Taichung Veterans General Hospital","RECRUITING","Taichung","407","Taiwan","TW",{"type":50,"coordinates":51},"Point",[52,53],120.6839,24.1469,{"lat":53,"lon":52},[56],{"name":37,"role":38,"phone":39,"phoneExt":24,"email":40},{"type":58,"investigatorFullName":37,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Doctor","100586262","ultrasonication-mediated-microbubbles-dressing-for-hand-arthritis-100586262",false,"NCT06913088","Ultrasonication-mediated Microbubbles Dressing for Hand Arthritis","Ultrasonication-mediated Microbubbles Dressings Increase the Therapeutic Efficacy of Piroxicam Gel for Hand Arthritis: Assessments Using Conventional and Ultrafast Power Doppler Imaging","Inclusion Criteria:\n\n* Clinical diagnosis of hand arthritis\n* Have at least three symptomatic joints over wrist, metacarpophalangeal joints, and interphalangeal joints\n\nExclusion Criteria:\n\n* Infectious arthritis\n* Acute gout","ALL","20 Years",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this clinical trial is to learn if ultrasonication-mediated microbubbles dressing works to treat hand arthritis in adults. It will also learn about the safety of ultrasonication-mediated microbubbles dressing. The main questions it aims to answer are:\n\nDoes ultrasonication-mediated microbubbles dressing increase the therapeutic efficacy of piroxicam gel for hand arthritis?\n\nResearchers will compare \"ultrasonication-mediated microbubbles dressing + piroxicam gel \" to \"ultrasonication + piroxicam gel\" and \"piroxicam gel alone\" to see if ultrasonication-mediated microbubbles dressing works to treat hand arthritis.\n\nParticipants will:\n\nTake \"ultrasonication-mediated microbubbles dressing (day 1,3,5) + piroxicam gel (day 2,4,6,7) \", \"ultrasonication (day 1,3,5) + piroxicam gel (day 2.4.6.7)\", and \"piroxicam gel alone (day 1-7)\" for 1 week.\n\nVisit the clinic on day 1 and day 8 for checkups and tests Keep a diary of their symptoms",[77],"Hand Arthritis","2025-04-14",{"date":80,"type":81},"2025-04-17","ACTUAL",{"date":83,"type":81},"2025-04-02",{"date":85,"type":71},"2026-03-31",{"name":5,"class":6},1]