[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602032":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":33,"collaborators":10,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":39,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":10,"studyType":51,"phases":10,"briefSummary":52,"conditions":53,"keywords":57,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Kocaeli University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Spastic CP Cohort",null,"Ambulatory children with spastic cerebral palsy classified within GMFCS levels I to III. Participants undergo clinical and ultrasound-based assessments to evaluate muscle morphology, functional properties, and their relationship with motor function.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Mustafa Kadıoğlu, MD","CONTACT","+90 262 303 75 00","mustafa.kadioglu@kocaeli.edu.tr",[19],{"facility":20,"status":21,"city":22,"state":10,"zip":10,"country":23,"countryCode":10,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Kocaeli University Faculty of Medicine","RECRUITING","Kocaeli","Turkey (Türkiye)",{"type":25,"coordinates":26},"Point",[27,28],27.51145,39.62497,{"lat":28,"lon":27},[31],{"name":14,"role":15,"phone":32,"phoneExt":10,"email":17},"(0262) 303 75 75",{"type":34,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Nigar Dursun","Principal Investigator, Department of Physical Medicine and Rehabilitation","100602032","ultrasonographic-assessment-of-muscle-morphology-function-and-clinical-findings-in-spastic-cerebral-palsy-100602032",false,"NCT07118228","Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy","Evaluation of the Relationship Between Ultrasonographic Muscle Morphology, Functional Properties, and Clinical Parameters in Children With Spastic Cerebral Palsy","US-sCP","Inclusion Criteria:\n\n* Diagnosis of spastic cerebral palsy (SCP) according to the criteria defined by Rosenbaum et al. (2007)\n* Age between 4 and 18 years\n* Gross Motor Function Classification System (GMFCS) Level I, II, or III\n* Manual Ability Classification System (MACS) Level I, II, III, or IV\n\nExclusion Criteria:\n\n* Non-spastic types of cerebral palsy (e.g., dyskinetic, ataxic)\n* Diagnosis of neuromuscular disorders other than cerebral palsy (e.g., hereditary neuropathy, myopathy)\n* Presence of muscle contractures or fixed deformities in the limbs selected for ultrasound and clinical assessment\n* Cognitive or behavioral impairments that prevent cooperation during ultrasound or clinical evaluation\n* Botulinum toxin-A (BoNT-A) injection applied to the target muscles within the last 6 months\n* Current treatment with oral or intrathecal antispastic medications\n* History of orthopedic surgery or selective dorsal rhizotomy involving the target muscles\n* Acute infection, febrile illness, or severe systemic disease (e.g., advanced heart failure, respiratory insufficiency) that may compromise the safety of assessments","ALL","4 Years","18 Years",{"count":49,"type":50},36,"ESTIMATED","OBSERVATIONAL","This study focuses on children with spastic cerebral palsy and aims to examine how muscle morphology and tissue characteristics, as assessed by ultrasound, may relate to functional motor abilities. It is designed as a prospective, cross-sectional, observational study. Planned ultrasound-based assessments include parameters such as muscle thickness, pennation angle, fascicle length, echo intensity, tissue stiffness (via shear wave elastography), and microvascular flow (via superb microvascular imaging). These measurements are intended to be compared with standard clinical evaluations, including the GMFCS, GMFM-66, MAS, MACS, and Tardieu Scale. The study seeks to contribute to a better understanding of the relationship between muscle architecture and functional outcomes, with the goal of generating insights that may inform individualized rehabilitation planning.",[54,55,56],"Muscle Spasticity","Gait Disorders, Neurologic","Cerebral Palsy, Spastic",[58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73],"Spastic Cerebral Palsy","Muscle Morphology","Shear Wave Elastography","Muscle Architecture","Superb Microvascular Imaging","Muscle Stiffness","Pennation Angle","Fascicle Length","Intramuscular Vascularity","Echo Intensity","GMFM-66","Gross Motor Function","Muscle Morphology and Function","Ultrasound Imaging","Ultrasound Imaging of Spastic Muscle","Functional Assessment","2026-01-30",{"date":76,"type":77},"2026-02-03","ACTUAL",{"date":79,"type":77},"2025-12-15",{"date":81,"type":50},"2026-06-30",{"name":5,"class":6},1]