[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591734":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":42,"centralContacts":43,"locations":49,"responsibleParty":73,"collaborators":42,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":42,"eligibilityCriteria":83,"healthyVolunteers":79,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":42,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":42,"overallStatus":51,"whyStopped":42,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","ACTIVE_COMPARATOR","Patients will receive o.5 ug\u002Fkg\u002Fhr fentanyl infusion all through the whole operation.",[13],"Drug: Control",{"label":15,"type":16,"description":17,"interventionNames":18},"Pectoral nerves group","EXPERIMENTAL","This group will receive fentanyl infusion at a dose of (0.5 μg\u002Fkg\u002Fhr) all through the whole operation, plus ultrasound guided bilateral pectoral nerves (PECS) Block which will be done by injecting 0.4 ml\u002Fkg (1:1 solution of bupivacaine 0.25% and lidocaine 1%) at each side .",[19],"Other: Pectoral nerves (PECS)",{"label":21,"type":16,"description":22,"interventionNames":23},"Transversus thoracic muscle plane block group","This group will receive fentanyl infusion at a dose of (0.5 μg\u002Fkg\u002Fhr) all through the whole operation, plus Ultrasound guided bilateral transversus thoracic muscle plane block (TTPB) which will be done by injecting 0.4 ml\u002Fkg (1:1 solution of bupivacaine 0.25% and lidocaine 1%) at each side .",[24],"Other: Transversus thoracic muscle plane block (TTPB)",[26,32,37],{"type":27,"name":28,"description":11,"armGroupLabels":29,"otherNames":30},"DRUG","Control",[9],[31],"Fentanyl",{"type":6,"name":33,"description":17,"armGroupLabels":34,"otherNames":35},"Pectoral nerves (PECS)",[15],[36],"Bupivacaine 0.25% and lidocaine 1%",{"type":6,"name":38,"description":22,"armGroupLabels":39,"otherNames":40},"Transversus thoracic muscle plane block (TTPB)",[21],[41],"Bupivacaine 0.25% and lidocaine 1%)",null,[44],{"name":45,"role":46,"phone":47,"phoneExt":42,"email":48},"Mai M Elfiky, Master","CONTACT","00201110404608","maielfiky45@gmail.com",[50],{"facility":5,"status":51,"city":52,"state":42,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Cairo","12613","Egypt","EG",{"type":57,"coordinates":58},"Point",[59,60],31.24967,30.06263,{"lat":60,"lon":59},[63,64,67,69,71],{"name":45,"role":46,"phone":47,"phoneExt":42,"email":48},{"name":65,"role":66,"phone":42,"phoneExt":42,"email":42},"Abdelhay A Ebade, MD","SUB_INVESTIGATOR",{"name":68,"role":66,"phone":42,"phoneExt":42,"email":42},"Ahmed K Mohammed, MD",{"name":70,"role":66,"phone":42,"phoneExt":42,"email":42},"Ahmed A Gado, MD",{"name":72,"role":66,"phone":42,"phoneExt":42,"email":42},"Mahmoud M Elwakeel, MD",{"type":74,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"PRINCIPAL_INVESTIGATOR","Mai Mohamed Mahmoud Elfiky","Assistant Lecturer of Anesthesia, Surgical ICU and Pain Management, Cairo University Hospitals.","100591734","ultrasound-guided-bilateral-pectoral-nerve-block-versus-bilateral-transverse-thoracic-plane-block-in-pediatric-patients-undergoing-corrective-cardiac-surgeries-requiring-cardiopulmonary-bypass-via-median-sternotomy-100591734",false,"NCT06984276","Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric Patients Undergoing Corrective Cardiac Surgeries Requiring Cardiopulmonary Bypass Via Median Sternotomy","Efficacy Of Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric Patients Undergoing Corrective Cardiac Surgeries Requiring Cardiopulmonary Bypass Via Median Sternotomy: A Randomized Controlled Trial.","Inclusion Criteria:\n\n* Age: 6 months - 7 years.\n* Gender: both sexs .\n* Risk Adjustment for Congenital Heart Surgery (RACHS) II and III.\n* Patients undergoing cardiac surgeries requiring cardiopulmonary bypass with midline sternotomy incision.\n\nExclusion Criteria:\n\n* Patients whose parents or legal guardians refuse to participate.\n* Preoperative mechanical ventilation.\n* Patients in coma, mental retardation, neurological disease, or on drugs affecting the behaviour.\n* Preoperative inotropic drug infusion.\n* (Bleeding disorders (drug induced i.e., coumadin; or genetic e.g. hemophilia; or acquired e.g. disseminated intravascular coagulation \\[DIC\\]), coagulopathy: Partial Thromboplastin Time (PTT) \\> 40 seconds, International Normalized Ratio (INR) \\> 1.4, platelet count \\\u003C 100x10⁹.\n* Known or suspected allergy to any of the studied drugs.\n* Severe pulmonary hypertension (mean resting blood pressure in pulmonary arteries is above 70mmHg).\n* Cardiopulmonary bypass time more than 90 minutes.\n* local infection.\n* Significant Renal impairment (creatinine more than 1.2mg\u002Fdl)\n* Aortic cross-clamp time more than 45 minutes.\n* Total time from induction till intensive Care Unit (ICU) transfer more than 4 hours and 30 mins.","ALL","6 Months","7 Years",{"count":88,"type":89},81,"ESTIMATED","INTERVENTIONAL",[92],"NA","This randomized, double-blinded, study aims to compare the efficacy of intraoperative and postoperative pain control while using bilateral ultrasound guided the pectoral nerves (PECS) versus transversus thoracic muscle plane block (TTPB) in pediatric patients undergoing corrective cardiac surgeries.",[95,96,97,98,99,100,101],"Ultrasound","Pectoral Nerve Block","Transverse Thoracic Plane Block","Pediatric Patients","Corrective Cardiac Surgeries","Cardiopulmonary Bypass","Median Sternotomy","2025-05-26",{"date":104,"type":105},"2025-05-30","ACTUAL",{"date":107,"type":105},"2024-09-30",{"date":109,"type":89},"2025-12-30",{"name":5,"class":6},1]