[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634131":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":57,"collaborators":11,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":11,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":11,"enrollmentInfo":70,"targetDuration":11,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":82,"overallStatus":42,"whyStopped":11,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Sana Klinikum Offenbach","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Anesthesiological, Ultrasound-Guided \"Erector Spine Plane Block\" (ESPB)","ACTIVE_COMPARATOR",null,[13],"Procedure: Anesthesiological, Ultrasound-Guided \"Erector Spine Plane Block\" (ESPB)",{"label":15,"type":10,"description":11,"interventionNames":16},"Surgical, Thoracoscopically-Guided \"Intercostal Nerve Block\" (ICNB)",[17],"Procedure: Surgical, Thoracoscopically-Guided \"Intercostal Nerve Block\" (ICNB)",[19,23],{"type":20,"name":9,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","The ultrasound-guided Erector Spinae Plane Block (ESPB) is performed by experienced anesthesiologists prior to induction of general anesthesia and before the start of surgery. Standard sterile precautions are applied. The fifth and sixth thoracic vertebrae are identified using anatomical landmarks and, if needed, ultrasound guidance. An ultrasound probe is positioned in a paramedian sagittal orientation approximately 2 cm lateral to the spinous process to visualize relevant anatomical structures. An in-plane needle technique is used, advancing the needle in a cranial-to-caudal direction under continuous ultrasound visualization. The needle tip is positioned in the subfascial plane beneath the erector spinae muscle at the level of the transverse process. Correct positioning is confirmed using hydrodissection. The local anesthetic is administered incrementally under continuous ultrasound guidance with repeated negative aspiration. A total of 25 mL of ropivacaine 0.375% is injected.",[9],{"type":20,"name":15,"description":24,"armGroupLabels":25,"otherNames":11},"The thoracoscopically-guided Intercostal Nerve Block (ICNB) is performed by the surgeon intraoperatively immediately after insertion of the thoracoscope and before the start of surgery. Standard sterile precautions are applied. The block is performed percutaneously under continuous thoracoscopic visualization. The needle is advanced to the intercostal space, targeting the neurovascular bundle in the costal groove. Injections are performed at the level of the trocar insertion and in the two intercostal spaces cranial and caudal to it. The spread of the local anesthetic is visualized thoracoscopically to ensure correct placement and to avoid pleural perforation. A volume of 5 mL is administered per level, resulting in a total of 25 mL of ropivacaine 0.375%.",[15],[27],{"name":28,"affiliation":29,"role":30},"Haitham Mutlak, Prof. Dr.","Department of Anesthesiology, Intensive Care Medicine and Pain Therapy at Sana Klinikum Offenbach","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":11,"email":36},"Prof. Dr. H. Mutlak","CONTACT","0049-69-8405-3802","haitham.mutlak@sana.de",{"name":38,"role":34,"phone":11,"phoneExt":11,"email":39},"E. Park, MD","eunji.park@sana.de",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Offenbach","Hesse","63069","Germany","DE",{"type":49,"coordinates":50},"Point",[51,52],8.76647,50.10061,{"lat":52,"lon":51},[55,56],{"name":33,"role":34,"phone":35,"phoneExt":11,"email":36},{"name":38,"role":34,"phone":11,"phoneExt":11,"email":39},{"type":30,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Haitham Mutlak","Head of Department of Anesthesiology","100634131","ultrasound-guided-erector-spinae-plane-block-versus-thoracoscopically-guided-intercostal-nerve-block-in-video-assisted-thoracoscopic-surgery-100634131",false,"NCT07535697","Ultrasound-Guided Erector Spinae Plane Block Versus Thoracoscopically-Guided Intercostal Nerve Block in Video-Assisted Thoracoscopic Surgery","Prospective, Randomized Comparative Study of an Anesthesiological, Ultrasound-Guided \"Erector Spinae Plane Block\" (ESPB) Versus a Surgical, Thoracoscopically-Guided \"Intercostal Nerve Block\" (ICNB) in \"Video-Assisted Thoracoscopic\" (VATS) Procedures, Evaluating Postoperative Analgesic Consumption, Postoperative Pain Perception, and Duration of the Procedure","Inclusion Criteria:\n\n* Provision of written informed consent\n* Adults (≥ 18 years of age)\n* Elective video-assisted thoracoscopic surgery (VATS) for pulmonary resection (e.g., lobectomy, segmentectomy, wedge resection)\n\nExclusion Criteria:\n\n* Lack of informed consent\n* Language barrier\n* Pregnancy or breastfeeding\n* Known allergy to local anesthetics used in the study\n* Infection at the injection site(s)\n* History of complex chest wall surgery\n* Revision surgery with a prior operation within the last 6 months\n* Intraoperative conversion to open thoracotomy\n* Chronic pain syndrome\n* Fibromyalgia\n* Chronic opioid use\n* Chronic alcohol abuse\n* Chronic substance abuse (e.g., THC, amphetamines, cocaine)\n* History of psychiatric disorders (e.g., depression, schizophrenia)\n* Impaired consciousness, cognition, or ability to communicate\n* Known coagulopathy (including platelet count \\\u003C 80,000\u002FµL or prolonged PTT\u002FaPTT \\>1.5× the upper limit of normal)\n* Ongoing therapeutic anticoagulation",true,"ALL","18 Years",{"count":71,"type":72},72,"ESTIMATED","INTERVENTIONAL",[75],"NA","Effective postoperative pain management is essential after thoracic surgery. Insufficient pain control may impair breathing and coughing, increasing the risk of pulmonary complications such as collapsed lungs (atelectasis) or pneumonia.\n\nAlthough minimally invasive lung surgery (video-assisted thoracoscopic surgery, VATS) is less painful than open surgery, people can still have significant pain after the operation.\n\nThe goal of this randomized comparative study is to compare two commonly used regional anesthesia techniques for pain control after VATS in adults.\n\nResearchers will compare an ultrasound-guided erector spinae plane block (ESPB), performed by anesthesiologists, to a thoracoscopically-guided intercostal nerve block (ICNB), performed by surgeons.\n\nParticipants will:\n\n* Undergo elective VATS lung resection surgery\n* Receive either ESPB or ICNB, according to random assignment\n* Have the received amount of analgesics recorded during the first 24 hours\n* Have their pain levels assessed at predefined time points after surgery\n\nThe main questions this study aims to answer are:\n\n* Does ESPB result in similar analgesic consumption in the first 24 hours after surgery?\n* Does ESPB provide similar postoperative pain relief compared to ICNB?\n* Is the time needed to perform ESPB similar to ICNB?",[78,79,80,81],"Regional Anesthesia","Video-assisted Thoracoscopic Surgery (VATS)","Erector Spinae Plane Block","Intercostal Nerve Block",[78,79,80,83,81,84],"ESPB","ICNB","2026-04-27",{"date":87,"type":88},"2026-05-01","ACTUAL",{"date":90,"type":72},"2026-05-04",{"date":92,"type":72},"2027-05-03",{"name":5,"class":6},1]