[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100279264":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":33,"locations":39,"responsibleParty":56,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Hospital Son Llatzer","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Real Pulsed Radiofrequency","ACTIVE_COMPARATOR","Before needle insertion, the patient's inferomedial (IM), superomedial (SM), and superolateral (SL) GN branches will be identified under ultrasound guidance. RF needles and probes will be advanced to each of the target nerves under ultrasound guidance. A 50 Hz-frequency sensorial stimulation will be applied with a threshold of \\\u003C 0.5 mA to identify the nerve position, the current intensity (mA) will be reduced at \\\u003C 0,2 mA. During the sensorial stimulation, the patients will be asked if they feel tingling, pain, or discomfort inside the knee. The RF probe will be maintained in place until one of those feelings is elicited. In order to avoid inactivating motor nerves, the nerve will be tested for the absence of fasciculation in the the lower extremity on stimulation of 0,5 mA at 2 Hz.",[13],"Procedure: Real Pulsed Radiofrequency",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Pulsed Radiofrequency","SHAM_COMPARATOR","Control patients will undergo the same procedure. The sensorial and motor stimulations will be applied too. The RF electrode will be then inserted through the cannula, and RF lesions will be simulated without applying pulsed RF treatment to the IM, SM and SL, GN branches for 8 minutes each GN branch and the temperature of the electrode tip was not raised.",[19],"Procedure: Sham Pulsed Radiofrequency",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Pulsed Radiofrequency uses radiofrequency current in short (20 ms), high-voltage bursts; the \"silent\" phase (480 ms) allows time for heat elimination, generally keeping the target tissue below 42° C. The Radiofrequency (RF) electrode will be inserted through the canula, and RF lesions will be generated by applying pulsed RF treatment to the inferomedial (IM), superomedial (SM), and superolateral (SL) GN branches for 8 minutes at 42°C.",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":27,"otherNames":25},[15],[29],{"name":30,"affiliation":31,"role":32},"Javier Mata, MD","Son Llatzer University Hospital","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":37,"email":38},"CONTACT","0034871201233","1600","jmata@hsll.es",[40],{"facility":31,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Palma","Balear Islands","07198","Spain","ES",{"type":48,"coordinates":49},"Point",[50,51],2.65024,39.56939,{"lat":51,"lon":50},[54],{"name":30,"role":35,"phone":55,"phoneExt":37,"email":38},"0034871202133",{"type":32,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Javier Mata","Chief of Section of Anesthesiology and Reanimation Department","100279264","ultrasound-guided-pulsed-radiofrequency-in-the-treatment-of-patients-with-osteoarthritis-knee-usprfgenoak-100279264",false,"NCT02915120","Ultrasound-Guided Pulsed Radiofrequency In The Treatment Of Patients With Osteoarthritis Knee (USPRFGENOAK)","Ultrasound-Guided Pulsed Radiofrequency Of The Genicular Nerves In The Treatment Of Patients With Osteoarthritis Knee Pain: Randomized, Double-Blind, Placebo Controled Trial","USPRFGENOAK","Inclusion Criteria:\n\n* Chronic knee pain with pain intensity of at least 4 out 10 on the VAS on most or all days for more than 3 months\n* Patients of either sex with primary osteoarthritis of one or both knees fulfilling diagnostic criteria for osteoarthritis knee laid down by American College of Rheumatology.\n* Patients also had to have a Kellgren-Lawrence (radiologic criterion) score of at least 2\n* Pain resistant to conventional therapy including NSAIDs, opioids, muscle relaxants, oral steroids, physical therapy, and intra-articular injection therapy.\n\nExclusion Criteria:\n\n* The patients with secondary osteoarthritis of knees\n* Associated systemic arthropathies, e.g. rheumatoid arthritis and gout\n* Previous radiofrequency ablation treatment for similar symptoms.\n* Intra-articular knee corticosteroid or hyaluronic acid injection in the past 3 months.\n* Active systemic or local infections at the site of proposed needle and electrode placement.\n* Coagulopathy or other bleeding disorder\n* Cognitive deficit.\n* Unstable medical or psychiatric illness.\n* Previous knee joint replacement surgery\n* Patients missing two or more appointments consecutively were excluded from the study","ALL","40 Years",{"count":70,"type":71},142,"ESTIMATED","INTERVENTIONAL",[74],"NA","The purpose of this study is to determine if patients with chronic painful knee osteoarthritis experience meaningful and long-term improvement in pain, function, and analgesic use after ultrasound-guided pulsed radiofrequency of the genicular nerves following a double diagnostic genicular nerve blocks.",[77],"Osteoarthritis, Knee",[79,80,81,82,83],"Knee pain","osteoarthritis","genicular nerve","ultrasonography","pulsed radiofrequency","2024-11-08",{"date":86,"type":87},"2024-11-12","ACTUAL",{"date":89,"type":87},"2017-03-27",{"date":91,"type":71},"2024-12",{"name":5,"class":6},1]