[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580454":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":30,"locations":36,"responsibleParty":56,"collaborators":29,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":29,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":29,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":29,"overallStatus":38,"whyStopped":29,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Rectus sheath block group","EXPERIMENTAL","Patients will receive rectus sheath block (20 ml bilaterally, bupivacaine 0.25%) after induction of general anesthesia.",[13],"Drug: Rectus sheath block",{"label":15,"type":10,"description":16,"interventionNames":17},"Intrathecal morphine group","Patients will receive 150 µg intrathecal morphine after induction of general anesthesia.",[18],"Drug: Intrathecal morphine",[20,26],{"type":21,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"DRUG","Rectus sheath block",[9],[25],"Bupivacaine 0.25%",{"type":21,"name":27,"description":16,"armGroupLabels":28,"otherNames":29},"Intrathecal morphine",[15],null,[31],{"name":32,"role":33,"phone":34,"phoneExt":29,"email":35},"Sarah A Afifi, MD","CONTACT","0501035864","Sarah606060@gmail.com",[37],{"facility":5,"status":38,"city":39,"state":29,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Cairo","11591","Egypt","EG",{"type":44,"coordinates":45},"Point",[46,47],31.24967,30.06263,{"lat":47,"lon":46},[50,51,54],{"name":32,"role":33,"phone":34,"phoneExt":29,"email":35},{"name":52,"role":53,"phone":29,"phoneExt":29,"email":29},"Sondos Afifi, MD","PRINCIPAL_INVESTIGATOR",{"name":55,"role":53,"phone":29,"phoneExt":29,"email":29},"Ahmed M Eldemerdash, MD",{"type":53,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Sarah Ahmed","Lecturer of Anesthesia, Intensive care, and pain management, Faculty of Medicine, Ain Shams University, Cairo, Egypt.","100580454","ultrasound-guided-rectus-sheath-block-versus-intrathecal-morphine-for-postoperative-analgesia-in-patients-undergoing-open-total-abdominal-hysterectomy-100580454",false,"NCT06837506","Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy","Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy: A Randomized Trial","Inclusion Criteria:\n\n* Age: 18 - 65 years old.\n* American Society of Anesthesiologists (ASA) physical status (I -II).\n* Patients undergoing open total abdominal hysterectomy.\n\nExclusion Criteria:\n\n* Hepatic, renal, or cardiac disease.\n* Any known allergy to local anesthetic.\n* Physical or mental conditions which may vague measuring postoperative pain following surgery.\n* History of chronic use of analgesic as nonsteroidal anti-inflammatory drugs (NSAIDs) or central nervous system (CNS) depressants as antiepileptic, and bleeding disorders.","FEMALE","18 Years","65 Years",{"count":70,"type":71},80,"ESTIMATED","INTERVENTIONAL",[74],"NA","This study aims to compare the effectiveness and safety of ultrasound-guided rectus sheath block versus intrathecal morphine for postoperative analgesia in patients undergoing open total abdominal hysterectomy.",[77,78,79,80,81],"Ultrasound","Rectus Sheath Block","Intrathecal Morphine","Postoperative Analgesia","Total Abdominal Hysterectomy","2025-02-20",{"date":84,"type":85},"2025-02-21","ACTUAL",{"date":82,"type":85},{"date":88,"type":71},"2025-08-01",{"name":5,"class":6},1]