[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638697":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":58,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":25,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":81,"overallStatus":85,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Sisli Hamidiye Etfal Training and Research Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"GROUP RSB","ACTIVE_COMPARATOR","Rectus Sheath Block:\n\nAfter completion of the operation, during the surgical closure phase, bilateral rectus sheath block will be performed. A linear ultrasound probe will be placed transversely over the umbilicus and 1 cm lateral to it. After visualization of the rectus abdominis muscle and posterior rectus sheath, a 22-Gauge 80 mm block needle (Braun Stimuplex Ultra-360, Melsungen, Germany) will be advanced from lateral to medial using the in-plane technique. Following hydrodissection with 1 mL saline between the rectus muscle and posterior sheath and confirmation of appropriate spread, 20 mL local anesthetic (0.25% bupivacaine) will be administered with intermittent negative aspiration.",[13],"Procedure: Rectus Sheath Block",{"label":15,"type":10,"description":16,"interventionNames":17},"GROUP LAI","Local Anesthetic Infiltration:\n\nAt the end of the operation, the surgeon will infiltrate 5 mL local anesthetic (0.5% bupivacaine) subcutaneously into each of the four trocar insertion sites.",[18],"Procedure: Local Anesthetic Infiltration",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Rectus Sheath Block","After completion of the operation, during the surgical closure phase, bilateral rectus sheath block will be performed. A linear ultrasound probe will be placed transversely over the umbilicus and 1 cm lateral to it. After visualization of the rectus abdominis muscle and posterior rectus sheath, a 22-Gauge 80 mm block needle (Braun Stimuplex Ultra-360, Melsungen, Germany) will be advanced from lateral to medial using the in-plane technique. Following hydrodissection with 1 mL saline between the rectus muscle and posterior sheath and confirmation of appropriate spread, 20 mL local anesthetic (0.25% bupivacaine) will be administered with intermittent negative aspiration.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Local Anesthetic Infiltration","At the end of the operation, the surgeon will infiltrate 5 mL local anesthetic (0.5% bupivacaine) subcutaneously into each of the four trocar insertion sites.",[15],[31],{"name":32,"affiliation":33,"role":34},"LEYLA KILINC","şişli etfal eğitim araştırma hastanesi","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","+90 532 417 02 44","leylaturkoglu@hotmail.com",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"MUSTAFA ALTINAY","05333914422","m_altinay@yahoo.com",[45],{"facility":46,"status":25,"city":47,"state":25,"zip":48,"country":49,"countryCode":25,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Sisli Hamidiye Etfal Training Hospital","Istanbul","34371","Turkey (Türkiye)",{"type":51,"coordinates":52},"Point",[53,54],28.94966,41.01384,{"lat":54,"lon":53},[57],{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},{"type":34,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Leyla Kılınc","associate professor","100638697","ultrasound-guided-rectus-sheath-block-versus-local-infiltration-100638697",false,"NCT07582029","Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration","Comparison of the Analgesic Effects of Local Anesthetic Infiltration and Ultrasound-Guided Rectus Sheath Block in Laparoscopic Cholecystectomy Operations: A Prospective Randomized Controlled Study","Inclusion Criteria:\n\n* ASA (American Society of Anesthesiologists) class I-II patients\n* Patients aged between 18 and 65 years\n* Patients undergoing laparoscopic cholecystectomy surgery\n\nExclusion Criteria:\n\n* ASA class III-IV patients\n* Patients undergoing emergency surgery\n* Relatives of patients who do not provide consent\n* Presence of chronic pain\n* Chronic opioid use\n* Presence of local anesthetic allergy\n* Ibuprofen allergy\n* Paracetamol allergy\n* Presence of infection at the block site\n* Coagulopathy\n* Increased intracranial pressure\n* Pre-existing neurological deficit\n* Severe organ failure\n* Mental retardation\n* Anatomical deformity","ALL","18 Years",{"count":71,"type":72},60,"ESTIMATED","INTERVENTIONAL",[75],"NA","Laparoscopic cholecystectomy is associated with significant postoperative pain originating from trocar sites, pneumoperitoneum, and visceral irritation. Both local anesthetic infiltration and ultrasound-guided rectus sheath block are commonly used regional analgesic techniques to reduce postoperative pain and opioid consumption. This prospective randomized controlled study aims to compare the effects of these two techniques on postoperative pain scores, opioid requirements, and analgesia-related adverse effects following laparoscopic cholecystectomy.",[78,79,80],"Cholelithiases","Cholecystitis","Postoperative Pain",[82,22,83,84],"Cholecystectomy, Laparoscopic","Anesthesia, Local","Pain, Postoperative","NOT_YET_RECRUITING","2026-05-06",{"date":88,"type":89},"2026-05-12","ACTUAL",{"date":88,"type":72},{"date":92,"type":72},"2026-12-12",{"name":5,"class":6},1]