[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589380":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":42,"locations":52,"responsibleParty":71,"collaborators":28,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":28,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":28,"enrollmentInfo":84,"targetDuration":28,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":97,"whyStopped":28,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Stanford University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group (stellate ganglion block)","EXPERIMENTAL","Patients will receive an ultrasound guided stellate ganglion block (SGB) with 10 ml of 0.5% ropivacaine.",[13,14],"Procedure: Stellate ganglion block","Drug: Ropivacaine",{"label":16,"type":17,"description":18,"interventionNames":19},"Control Group (sham injection with saline)","SHAM_COMPARATOR","Patients will receive a subcutaneous sham injection with saline. Ultrasound imaging will be used to simulate the guidance process as in the active procedure, maintaining consistency in the procedural experience.",[20,21],"Procedure: Sham injection of saline","Drug: Normal saline",[23,29,33,38],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","Stellate ganglion block","Patients will receive a SGB",[9],null,{"type":24,"name":30,"description":31,"armGroupLabels":32,"otherNames":28},"Sham injection of saline","Patients will receive a subcutaneous sham injection of saline",[16],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":28},"DRUG","Ropivacaine","The SGB group will receive ropivacaine 0.5% 10ml",[9],{"type":34,"name":39,"description":40,"armGroupLabels":41,"otherNames":28},"Normal saline","The control group will receive normal saline in the sham injection.",[16],[43,48],{"name":44,"role":45,"phone":46,"phoneExt":28,"email":47},"Anna Maria Bombardieri, MD, PhD","CONTACT","3143269107","abomba@stanford.edu",{"name":49,"role":45,"phone":50,"phoneExt":28,"email":51},"Ksenia Kasimova, MD","6507889458","kasimova@stanford.edu",[53,66],{"facility":54,"status":28,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":28},"Stanford University School of Medicine","Stanford","California","94304","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-122.16608,37.42411,{"lat":64,"lon":63},{"facility":5,"status":28,"city":55,"state":56,"zip":67,"country":58,"countryCode":59,"cosmosGeoPoint":68,"geoPoint":70,"contacts":28},"94305",{"type":61,"coordinates":69},[63,64],{"lat":64,"lon":63},{"type":72,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"PRINCIPAL_INVESTIGATOR","Anna Maria Bombardieri","Clinical Associate Professor","100589380","ultrasound-guided-stellate-ganglion-block-in-postural-tachycardia-syndrome-100589380",false,"NCT06953661","Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome","Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome: A Randomized Double Blind Sham Placebo-controlled Pilot Study","Inclusion Criteria:\n\n* Adult patients (\\>18 years of age) diagnosed with POTS\n* Ability to provide informed consent\n* Ability to comply with 3 follow up visits\n* English speaking and capable of signing informed consent and complying with protocol requirements\n\nExclusion Criteria:\n\n* Allergy to local anesthetics\n* Severe coagulopathy\n* History of or currently being treated for clinically significant ongoing cardiac arrhythmia, heart failure, myocarditis, pulmonary embolism requiring anticoagulation, pulmonary fibrosis or other pulmonary diagnosis that in the investigator's opinion may contribute to symptoms of POTS\n* Inability to maintain a stable medication regiment for the duration of the study","ALL","18 Years",{"count":85,"type":86},20,"ESTIMATED","INTERVENTIONAL",[89],"NA","This single-center study aims to evaluate both immediate and long-term outcomes of stellate ganglion block (SGB) in a cohort of rigorously phenotyped patients with Postural Tachycardia Syndrome (POTS). By assessing the effects of SGB, this study seeks to determine its viability as an intervention for symptom control in POTS.",[92],"Postural Tachycardia Syndrome",[94,95,96],"stellate ganglion block","regional anesthesia","nerve block","NOT_YET_RECRUITING","2025-10-10",{"date":100,"type":101},"2025-10-15","ACTUAL",{"date":103,"type":86},"2025-10-13",{"date":105,"type":86},"2026-11",{"name":5,"class":6},2]