[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639374":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":39,"locations":47,"responsibleParty":63,"collaborators":26,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":26,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":26,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":87,"overallStatus":94,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Real fNIRS Neurofeedback and SmartPhone Intervention Arm","EXPERIMENTAL","Participants assigned to the experimental arm will see their true, real-time brain activation (i.e., active real-time neurofeedback) during the neurofeedback session. This activation will be displayed to the participant as a thermometer that will increase as brain activation in the target region increases. During the 4 week text-messaging intervention after neurofeedback, the active real-time neurofeedback group will be prompted to use neurofeedback strategies that increased their real PFC activation. Participants will also be directed to use these strategies in response to any unexpected urges each day.",[13,14],"Other: Real fNIRS Neurofeedback","Other: SmartPhone Intervention",{"label":16,"type":17,"description":18,"interventionNames":19},"Sham-Control fNIRS Neurofeedback and SmartPhone Intervention Arm","SHAM_COMPARATOR","Participants assigned to the sham-control arm will see false feedback (or a fake signal) during the neurofeedback session. During the 4 week text-messaging intervention after neurofeedback, the sham neurofeedback group will be prompted to use neurofeedback strategies they reported using when the sham feedback they saw was highest. Participants will also be directed to use these strategies in response to any unexpected urges each day.",[20,14],"Other: Sham-Control fNIRS Neurofeedback",[22,27,31],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Real fNIRS Neurofeedback","Participants will be instructed to use real-time fNIRS neurofeedback to non-invasively regulate neural activation associated with symptoms in individuals with bulimia nervosa. During the training, participants will view images on a computer screen, listen to sounds, and consume a shake.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham-Control fNIRS Neurofeedback","Participants will be instructed to use sham-control fNIRS neurofeedback to non-invasively regulate neural activation associated with symptoms in individuals with bulimia nervosa. During the training, participants will view images on a computer screen, listen to sounds, and consume a shake.",[16],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"SmartPhone Intervention","Over the subsequent 4 weeks, at the specific times when each individual is most likely to engage in eating disorder symptoms, participants will receive personalized messages to use mental strategies from their real-time or their sham-control fNIRS neurofeedback.",[9,16],[36],{"name":37,"affiliation":5,"role":38},"Laura A. Berner, Ph.D.","PRINCIPAL_INVESTIGATOR",[40,45],{"name":41,"role":42,"phone":43,"phoneExt":26,"email":44},"Sila Sozeri, B.A.","CONTACT","(212) 201-2679","sila.sozeri@mssm.edu",{"name":37,"role":42,"phone":26,"phoneExt":26,"email":46},"laura.berner@mssm.edu",[48],{"facility":49,"status":26,"city":50,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Center for Computational Psychiatry at the Icahn School of Medicine at Mount Sinai","New York","10027","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-74.00597,40.71427,{"lat":58,"lon":57},[61],{"name":62,"role":38,"phone":26,"phoneExt":26,"email":26},"Laura A. Berner",{"type":38,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Laura Berner","Associate Professor of Psychiatry","100639374","understanding-and-targeting-self-regulatory-control-in-bulimia-nervosa-100639374",false,"NCT07581158","Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa","Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa Via a Combined Real-Time Neurofeedback and Smartphone Intervention","Inclusion criteria:\n\n* Female\n* Aged 18 to 55 years\n* Meet diagnostic criteria for bulimia nervosa (BN) or BN of low frequency and\u002For limited duration\n* Current body mass index greater than or equal to 18.5kg\u002Fm2 but under 40kg\u002Fm2\n* English-speaking\n\nExclusion criteria:\n\n* Ongoing medical treatment or planned\u002Frecent change in medical treatment, major medical condition, or psychiatric disorder that may interfere with study variables or participation\n* Current psychotherapy focused primarily on eating disorder symptoms\n* Pregnancy or planned pregnancy, or lactation during the study period\n* Allergy to ingredients in the shake","FEMALE","18 Years","55 Years",{"count":77,"type":78},40,"ESTIMATED","INTERVENTIONAL",[81],"NA","The purpose of this study is to examine the effects of noninvasive prefrontal cortex (PFC) neurofeedback during eating in women with bulimia nervosa (BN) using wearable brain imaging, functional near-infrared spectroscopy (fNIRS), together with a brain-based 4-week text-messaging intervention. The investigators will examine how these interventions may influence inhibitory control and eating disorder symptoms in women with bulimia nervosa.",[84,85,86],"Bulimia Nervosa","Feeding and Eating Disorders","Mental Disorders",[88,89,90,91,92,93],"fNIRS","fNIRS neurofeedback","smartphone intervention","eating disorders","bulimia nervosa","bulimia","NOT_YET_RECRUITING","2026-05-06",{"date":97,"type":98},"2026-05-12","ACTUAL",{"date":100,"type":78},"2026-04-25",{"date":102,"type":78},"2028-12-14",{"name":5,"class":6},1]