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An ultrasound probe located at the end of the endoscope allows direct visualisation of the oesophageal wall layers and adjacent tissues providing local assessment of the depth of tumour invasion and lymph nodes. This assessment informs local tumour (T-) and node (N-) staging which are important prognostic indicators of survival. Patients undergoing EUS require sedation and there are risks of complication. EUS is a specialist investigation requiring many years of dedicated training to perform competently.",[14],{"name":15,"affiliation":16,"role":17},"Kieran Foley","Chief Investigator, based at Velindre University NHS Trust","PRINCIPAL_INVESTIGATOR",[19],{"name":20,"role":21,"phone":22,"phoneExt":7,"email":23},"Ben Lindfield","CONTACT","023 8120 5154","value@soton.ac.uk",[25,41,50,64,76,86,100,114,126,137,149,161,175,187],{"facility":26,"status":27,"city":28,"state":7,"zip":7,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Cwm Taf UHB","RECRUITING","Abercynon","United Kingdom","UK",{"type":32,"coordinates":33},"Point",[34,35],-3.32727,51.64548,{"lat":35,"lon":34},[38],{"name":39,"role":21,"phone":7,"phoneExt":7,"email":40},"Lauren Geen","lauren.geen@wales.nhs.uk",{"facility":42,"status":43,"city":44,"state":7,"zip":7,"country":29,"countryCode":30,"cosmosGeoPoint":45,"geoPoint":49,"contacts":7},"Royal Bournemouth 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Patients aged 16 or above with first diagnosis of biopsy-confirmed oesophageal cancer.\n2. Referred for EUS examination as part of standard of care investigations.\n3. Tumour location in the oesophagus, or gastro-oesophageal junction (Siewert types I-III)\n4. MDT decision that patient is potentially curable with radical treatment (e.g., endoscopic treatment, surgery +\u002F- neoadjuvant therapy, or definitive chemoradiotherapy)\n5. Prior staging with CT and PET-CT\n6. Eastern Cooperative Oncology Group (ECOG) performance status 0-2\n7. Clinical staging of T1-T4, N0-N3, M0 disease\n8. Adenocarcinoma or squamous cell carcinoma (SCC) histopathological cell type\n\n   Exclusion Criteria:\n9. Recurrent or residual disease\n10. Distant metastatic disease detected before EUS.\n11. Previous oesophagectomy or oesophageal radiotherapy\n12. Unable to undergo EUS examination.\n13. Concurrent malignancy e.g., second primary tumour\n14. Other histopathological cell type","ALL","16 Years",{"count":218,"type":219},160,"ESTIMATED","6 Months","OBSERVATIONAL","This is an observational trial that will look at patients undergoing endoscopic ultrasound (EUS) in patients with oesophageal cancer and to determine the proportion of cases in which EUS changes disease management in these patients.",[224],"Oesophageal Cancer","2026-04-24",{"date":227,"type":228},"2026-04-30","ACTUAL",{"date":230,"type":228},"2024-06-27",{"date":232,"type":219},"2026-12-31",{"name":5,"class":6},14]