[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100287687":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":31,"responsibleParty":47,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Universitaire Ziekenhuizen KU Leuven","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"MCDA cohort",null,"Unselected monochorionic diamniotic (MCDA) twin pregnancies, included between 11 and 14 weeks of gestation",{"label":13,"type":10,"description":14,"interventionNames":10},"TTTS cohort","Pregnancies complicated by twin-twin transfusion syndrome (TTTS) undergoing laser treatment, included at the time of diagnosis or referral",{"label":16,"type":10,"description":17,"interventionNames":10},"sIUGR cohort","Pregnancies complicated by selective intrauterine growth restriction (sIUGR), included at the time of diagnosis or referral. We define sIUGR as a discordance in estimated fetal weight of ≥ 20%.",[19],{"name":20,"affiliation":21,"role":22},"Liesbeth Lewi","UZ Leuven","STUDY_CHAIR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Isabel Couck","CONTACT","+32 16 34 22 94","isabel.couck@uzleuven.be",{"name":20,"role":26,"phone":10,"phoneExt":10,"email":30},"liesbeth.lewi@uzleuven.be",[32],{"facility":21,"status":33,"city":34,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Leuven","Belgium","BE",{"type":38,"coordinates":39},"Point",[40,41],4.70093,50.87959,{"lat":41,"lon":40},[44,46],{"name":45,"role":26,"phone":10,"phoneExt":10,"email":10},"Isabe Couck",{"name":20,"role":26,"phone":10,"phoneExt":10,"email":10},{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100287687","unequal-placental-sharing-in-monochorionic-diamniotic-twins-an-observational-study-100287687",false,"NCT03024918","Unequal Placental Sharing in Monochorionic Diamniotic Twins: an Observational Study","Unequal Placental Sharing in Monochorionic Diamniotic Twins: an Observational Study to Investigate Prediction and Outcome: the TWINSHARE Study","TWINSHARE","Inclusion Criteria:\n\n* MCDA cohort\n\n  * Ongoing monochorionic diamniotic twin pregnancy between 11 and 14 weeks, as determined by the crown rump length of the larger twin in spontaneous conceptions and by the date of insemination or embryonic age at replacement in pregnancies resulting from subfertility treatment\n  * Women aged 18 years or more, who are able to consent\n  * Written informed consent to participate in this study, forms being approved by the Ethical Committees\n* TTTS cohort\n\n  * Monochorionic diamniotic twin pregnancy, with gestational age defined in the first trimester as mentioned above\n  * Complicated by TTTS according to the definition used in the Quintero staging of TTTS (DVP of donor \\\u003C 2 cm and DVP of receptor \\> 8 cm before 20 weeks or \\> 10 cm after 20 weeks\n  * Undergoing laser surgery for TTTS\n  * Women aged 18 years or more, who are able to consent\n  * Written informed consent to participate in this study, forms being approved by the Ethical Committees\n* sIUGR cohort\n\n  * Monochorionic diamniotic twin pregnancy, with gestational age defined in the first trimester as mentioned above\n  * Complicated by sIUGR defined as a discordance in EFW of ≥ 20%, with the percentage of discordance being calculated as (EFW larger twin - EFW smaller twin)\u002FEFW larger twin x 100.\n  * Women aged 18 years or more, who are able to consent\n  * Written informed consent to participate in this study, forms being approved by the Ethical Committees\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Inability to consent","FEMALE","18 Years",{"count":60,"type":61},393,"ESTIMATED","OBSERVATIONAL","This is an observational study in 3 cohorts of monochorionic diamniotic (MCDA) twins. The aim of the study is to assess whether unequal placental sharing can be predicted in pregnancy and whether it is predictive of pregnancy outcome.",[65],"Monochorionic Twins",[67,68],"monochorionic","placental sharing","2024-07-09",{"date":71,"type":72},"2024-07-10","ACTUAL",{"date":74,"type":72},"2016-04",{"date":76,"type":61},"2025-12",{"name":5,"class":6},1]