[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561653":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":18,"responsibleParty":39,"collaborators":42,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":7,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":7,"briefSummary":63,"conditions":64,"keywords":70,"overallStatus":20,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Uppsala University Hospital","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Martina Isaksson","CONTACT","0706954108","martina.isaksson@uu.se",{"name":15,"role":11,"phone":16,"phoneExt":7,"email":17},"Mia Ramklint","0730949181","mia.ramklint@uu.se",[19],{"facility":5,"status":20,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"RECRUITING","Uppsala","Uppsala County","75185","Sweden","SE",{"type":27,"coordinates":28},"Point",[29,30],17.63889,59.85882,{"lat":30,"lon":29},[33,36],{"name":34,"role":11,"phone":35,"phoneExt":7,"email":13},"Martina Isaksson, PhD","+46706954108",{"name":37,"role":11,"phone":38,"phoneExt":7,"email":17},"Mia Ramklint, PhD","+46730949181",{"type":40,"investigatorFullName":10,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","licensed psychologist, PhD, clinical researcher",[43,46],{"name":44,"class":45},"The Söderström König Foundation","UNKNOWN",{"name":47,"class":48},"Forte","INDUSTRY","100561653","unfolding-severe-and-enduring-eating-disorders-u-seed-100561653",false,"NCT06592963","Unfolding Severe and Enduring Eating Disorders (U-SEED)","U-SEED","For aim 1 (register based cohort):\n\nIncl. criteria:\n\nAttended care for eating disorders at Uppsala University Hospital between 2005 and 2007 and accepted to be included in a local quality register.\n\nExcl. criteria: None\n\nFor aim 2 (ongoing SEED sample and register based cohort)\n\nIncl. criteria:\n\n* For ongoing SEED sample: Minimum age of 18, impairing eating disorder symptoms for at least seven years, and having at least one evidence-based treatment without remission or resulting in relapse.\n* For register based cohort, see above.\n\nExcl. criteria:\n\n* For ongoing SEED sample: Eating disorders symptoms in need of emergency care, high risk for suicide, and an inability to respond to the questionnaires due to lack of knowledge in Swedish.\n\nFor aim 3 and 4 (the ongoing SEED sample). See above.","ALL","18 Years",{"count":59,"type":60},50,"ESTIMATED","2 Weeks","OBSERVATIONAL","The main aim of this study is to identify biological and psychological characteristics as risk factors in individuals with severe and enduring eating disorders (SEED).\n\nSpecifically, the investigators aim to:\n\n1. in a cohort of well-diagnosed eating disorder patients from 2005 followed up in National health registers, explore risk factors at baseline (recorded 2005-2007) for development of later SEED (the registry based cohort).\n2. replicate the findings in a new sample of 50 adults with ongoing SEED. Participants will be assessed diagnostically and physically, and asked to fill out questionnaires and leave blood samples (the ongoing SEED sample compared with the register based cohort).\n3. in a sample of 50 adults with SEED, explore demographic, biological, clinical, and psychological factors and examine the relation between these factors and symptom severity and functional impairment (the ongoing SEED sample).\n4. explore participants perspectives on their symptoms and received care (the ongoing SEED sample).",[65,66,67,68,69],"Eating Disorders","Anorexia Nervosa","Bulimia Nervosa","Binge-Eating Disorder","Personality Disorders",[71,72],"Registers","Severe and Enduring Eating Disorders","2024-09-09",{"date":75,"type":76},"2024-09-19","ACTUAL",{"date":78,"type":76},"2024-06-01",{"date":80,"type":60},"2026-04",{"name":5,"class":6},1]