[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637399":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":64,"collaborators":21,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":21,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":21,"enrollmentInfo":76,"targetDuration":21,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":21,"overallStatus":96,"whyStopped":21,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Risk group","ACTIVE_COMPARATOR","Lung ventilated during cardiopulmonary bypass using single-lung ventilation via double-lumen tube.",[13,14],"Procedure: Ventilated lung","Procedure: Non-ventilated lung.",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"PROCEDURE","Ventilated lung","This lung will be ventilated during cardiopulmonary bypass using volume-controlled ventilation with a tidal volume of 3 mL\u002Fkg ideal body weight, a PEEP of 5 cmH2O, a respiratory rate of 10\u002Fmin, and a fraction of inspired oxygen of 30%.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Non-ventilated lung.","The contralateral lung will not be ventilated during cardiopulmonary bypass and will be allowed to collapse.",[9],[27],{"name":28,"affiliation":5,"role":29},"Martin Dworschak, MD, MBA","PRINCIPAL_INVESTIGATOR",[31,36],{"name":28,"role":32,"phone":33,"phoneExt":34,"email":35},"CONTACT","+43-1-40400","41090","martin.dworschak@meduniwien.ac.at",{"name":37,"role":32,"phone":33,"phoneExt":38,"email":39},"Edda M. Tschernko, MD, MBA","41060","edda.tschernko@meduniwien.ac.at",[41],{"facility":42,"status":21,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"General Hospital Vienna","Vienna","State of Vienna","1090","Austria","AT",{"type":49,"coordinates":50},"Point",[51,52],16.37208,48.20849,{"lat":52,"lon":51},[55,56,57,58,60,62],{"name":28,"role":32,"phone":33,"phoneExt":34,"email":35},{"name":37,"role":32,"phone":33,"phoneExt":38,"email":39},{"name":28,"role":29,"phone":21,"phoneExt":21,"email":21},{"name":37,"role":59,"phone":21,"phoneExt":21,"email":21},"SUB_INVESTIGATOR",{"name":61,"role":59,"phone":21,"phoneExt":21,"email":21},"Keso Skhirtladze-Dworschak, MD",{"name":63,"role":59,"phone":21,"phoneExt":21,"email":21},"Florentina Zingher, MD",{"type":29,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Dr. Martin Dworschak","Ao.Univ. Prof. Dr.","100637399","unilateral-ventilation-on-cardiopulmonary-bypass-during-cardiac-surgery-100637399",false,"NCT07612709","Unilateral Ventilation on Cardiopulmonary Bypass During Cardiac Surgery","Unilateral Ventilation on Cardiopulmonary Bypass During Cardiac Surgery in Patients at Increased Risk for Severe Postoperative Pulmonary Complications","Inclusion Criteria:\n\n* Patients at increased risk for postoperative pulmonary complications\n* Major elective cardiac surgery\n* Prolonged duration of cardiopulmonary bypass\n* Patients older than 65 years of age\n* Informed consent\n\nExclusion Criteria:\n\n* Emergency\n* Urgent procedures\n* Patients with implanted pacemakers\n* Patients with internal cardioverter\u002Fdefibrillators\n* Decompensated cardiac disease\n* Pulmonary disease\n* Recent pneumonia\n* Need for temporary perioperative mechanical support\n* Patients not willing to participate\n* Treatment with inhaled nitric oxide","ALL","65 Years",{"count":77,"type":78},45,"ESTIMATED","INTERVENTIONAL",[81],"NA","This study investigates if single lung ventilation on cardiopulmonary bypass can mitigate postoperative lung water accumulation determined by lung ultrasound in the ventilated lung as compared to the non-ventilated lung in patients at high-risk for developing severe pulmonary complications after cardiac surgery.",[84,85,86,87,88,89,90,91,92,93,94,95],"Lung Protective Ventilation","Cardiopulmonary Bypass","High-risk Cardiac Patients","Lung Ultrasound","Lung Water Assessment","Pulmonary Complications in Surgical Patients","Single-lung Ventilation","Chest X-ray for Clinical Evaluation","Electrical Impedance Tomography (EIT)","Lung Compliance","Oxygenation Indices","Biomarkers of Vascular Endothelial Injury","NOT_YET_RECRUITING","2026-05-24",{"date":99,"type":100},"2026-05-29","ACTUAL",{"date":102,"type":78},"2026-10-01",{"date":104,"type":78},"2029-07-31",{"name":5,"class":6},1]