[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639438":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":31,"locations":36,"responsibleParty":56,"collaborators":60,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":18,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":90,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Uppsala University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Screening","EXPERIMENTAL","Home cardiovascular screening package: 7-day home BP measurement; dried blood spot self-sampling for ApoB, HbA1c and creatinine; digital questionnaire on lifestyle, symptoms, family history, diagnoses, medications. Above-threshold findings trigger initiation of guideline-recommended pharmacotherapy and referral to clinical care.",[13],"Behavioral: Home-based multimodal cardiovascular screening",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Usual care. No active screening offered as part of trial. Outcomes via national register and EHR linkage.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Home-based multimodal cardiovascular screening","Self-administered home-based screening program: 7-day home BP, DBS biomarker self-sampling, digital questionnaire; structured digital return of results; threshold-based initiation of guideline-recommended pharmacotherapy and referral to clinical care.",[9],[26,29],{"name":27,"affiliation":5,"role":28},"Johan Sundström, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":30,"affiliation":5,"role":28},"Anders Wanhainen, MD, PhD",[32],{"name":27,"role":33,"phone":34,"phoneExt":18,"email":35},"CONTACT","+46 70 422 52 20","johan.sundstrom@uu.se",[37],{"facility":38,"status":39,"city":40,"state":18,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Uppsala University Hospital","RECRUITING","Uppsala","751 85","Sweden","SE",{"type":45,"coordinates":46},"Point",[47,48],17.63889,59.85882,{"lat":48,"lon":47},[51,53,54],{"name":52,"role":33,"phone":34,"phoneExt":18,"email":35},"Sundström",{"name":52,"role":28,"phone":18,"phoneExt":18,"email":18},{"name":55,"role":28,"phone":18,"phoneExt":18,"email":18},"Wanhainen",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Johan Sundström","Professor of Epidemiology, Consultant in Cardiology",[61],{"name":62,"class":63},"Region Uppsala","UNKNOWN","100639438","uppsala-self-screening-of-cardiovascular-health-100639438",false,"NCT07614659","Uppsala Self-Screening of Cardiovascular Health","Uppsala Self-Screening of Cardiovascular Health: A Randomized Controlled Trial of Home-Based Multimodal Cardiovascular Screening Versus Usual Care in Middle-Aged and Older Adults","U-SCREEN","Inclusion Criteria:\n\n* Resident in Region Uppsala, Sweden\n* Turning 50, 55, 60, 65, 70 or 75 years during recruitment period\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Inability to provide informed consent\n* Protected identity",true,"ALL","50 Years","75 Years",{"count":77,"type":78},45000,"ESTIMATED","INTERVENTIONAL",[81],"NA","U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can identify clinically actionable cardiovascular risk factors more effectively than usual care. Participants randomized to the screening arm receive a home blood pressure measurement device, a dried blood spot sampling kit (for ApoB, HbA1c and creatinine), and a digital questionnaire. The control arm receives usual care. Recruitment runs 2024-2027 with a target identification of 10,000 cardiovascular risk conditions.",[84,85,86,87,88,89],"Cardiovascular Diseases","Hypertension","Dyslipidemias","Diabetes Mellitus","Atrial Fibrillation","Chronic Kidney Disease",[91,92,93,94,95,96,97],"Population screening","Cardiovascular prevention","Home blood pressure monitoring","Dried blood spot","Digital health","Pragmatic trial","Register-based randomized controlled trial","2026-06-26",{"date":100,"type":101},"2026-06-30","ACTUAL",{"date":103,"type":101},"2025-02-01",{"date":105,"type":78},"2037-12",{"name":58,"class":6},1]