[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566620":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":29,"centralContacts":37,"locations":43,"responsibleParty":59,"collaborators":29,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":29,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":29,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":46,"whyStopped":29,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"University of Copenhagen","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal conditions","ACTIVE_COMPARATOR","Urine samples collected after various performance tests in normal conditions",[13],"Other: Normal conditions",{"label":15,"type":16,"description":17,"interventionNames":18},"Heated conditions","EXPERIMENTAL","Urine samples collected after various performance tests in heated conditions",[19],"Other: Heated conditions",{"label":21,"type":6,"description":22,"interventionNames":23},"Salmeterol inhalation and urine samples","Participants are administered daily salmeterol inhalation from an MDI device and are required to collect spot urine samples at home.",[24],"Drug: Salmeterol inhalation and urine samples",[26,30,33],{"type":6,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"Participants are administered salmeterol, after which they perform various performance tests in normal conditions. Following the administration of salmeterol, urine samples are collected over the next 24 hours at intervals of 0.5, 1, 2, 4, 8, and 24 hours after administration.",[9],null,{"type":6,"name":15,"description":31,"armGroupLabels":32,"otherNames":29},"Participants are administered salmeterol, after which they perform various performance tests in heated conditions. Following the administration of salmeterol, urine samples are collected over the next 24 hours at intervals of 0.5, 1, 2, 4, 8, and 24 hours after administration.",[15],{"type":34,"name":21,"description":35,"armGroupLabels":36,"otherNames":29},"DRUG","After the experimental day under normal conditions, all participants are administered 200 µg of salmeterol daily (8 puffs from the MDI device) during a 6-day intervention period. Two hours after inhalation, the participants collect spot urine samples at home",[21],[38],{"name":39,"role":40,"phone":41,"phoneExt":29,"email":42},"Morten Hostrup, PhD","CONTACT","+4535321595","mhostrup@nexs.ku.dk",[44],{"facility":45,"status":46,"city":47,"state":29,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"August Krogh Building","RECRUITING","Copenhagen","2100","Denmark","DK",{"type":52,"coordinates":53},"Point",[54,55],12.56553,55.67594,{"lat":55,"lon":54},[58],{"name":39,"role":40,"phone":41,"phoneExt":29,"email":42},{"type":60,"investigatorFullName":39,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Associate Professor","100566620","urinary-concentration-after-salmeterol-100566620",false,"NCT06657547","Urinary Concentration After Salmeterol","Urinary Concentration After Salmeterol in Well-trained Men and Females","Inclusion Criteria:\n\n* Inclusion Criteria:\n* Age 18-40\n* Physically active \\>5 hours a week\n* Maximum oxygen uptake classified as high or very high\n\nExclusion Criteria:\n\n* Active smoker currently or within the past 5 years\n* Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)\n* Chronic or acute illness deemed by the responsible study physician to affect the test parameters\n* Deviation from the study protocol\n* Lean mass index \\>21 kg\u002Fm²\n* Pregnancy\n* Smoker\n* Blood donation during the past 3 months","ALL","18 Years","40 Years",{"count":73,"type":74},24,"ESTIMATED","INTERVENTIONAL",[77],"NA","The purpose of the project is to investigate urine concentration after inhalation of salmeterol. This will be examined following acute physical activity under both normal conditions and heated conditions.",[80],"Healthy",[82,83],"Urinary concentration","Beta2-adrenergic stimulation","2025-04-07",{"date":86,"type":87},"2025-04-09","ACTUAL",{"date":89,"type":87},"2024-10-31",{"date":91,"type":74},"2026-12-31",{"name":5,"class":6},1]