[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100464247":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":53,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":26,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":81,"overallStatus":83,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"POPRC group","EXPERIMENTAL","pelvic-organ preserving radical cystectomy with orthotopic ileal neobladder",[13],"Procedure: POPRC+OIN",{"label":15,"type":16,"description":17,"interventionNames":18},"SRC group","ACTIVE_COMPARATOR","standard radical cystectomy with orthotopic ileal neobladder",[19],"Procedure: SRC+OIN",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","POPRC+OIN","Pelvic-organ preserving radical cystectomy with orthotopic ileal neobladder",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"SRC+OIN","Standard radical cystectomy with orthotopic ileal neobladder",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Wenlong Zhong, MD","CONTACT","86-18510904167","zhongwlong3@mail.sysu.edu.cn",[38],{"facility":39,"status":26,"city":40,"state":41,"zip":26,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Sun Yat-Sen Memorial Hospital","Guangzhou","Guangdong","China","CN",{"type":45,"coordinates":46},"Point",[47,48],113.25,23.11667,{"lat":48,"lon":47},[51],{"name":52,"role":34,"phone":35,"phoneExt":26,"email":36},"Wenlong Zhong",{"type":54,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[56],{"name":57,"class":6},"Peking University Third Hospital","100464247","urinary-continence-of-female-poprc-and-oin-100464247",false,"NCT05325216","Urinary Continence of Female POPRC and OIN","Urinary Continence of Female Pelvic Organ-preserving Radical Cystectomy and Orthotopic Ileal Neobladder: A Randomized Controlled Study","Inclusion Criteria:\n\n1. Female patients aged between 55-75.\n2. Patients those who are diagnosed with organ-confined urothelial carcinoma（\\\u003CpT3）\n3. Patients those who are capable for radical cystectomy with orthotopic ileal neobladder.\n4. ECOG score between 0-2;\n5. Normal renal function;\n6. Patients those who volunteer to participate in this study and sign the informed consents.\n7. Patients those who are able to cooperate in the study.\n\nExclusion Criteria:\n\n1. Absence of tumour in bladder neck or urethra;\n2. Patients thsoe who are diagnosed distant metastasis before surgery.\n3. Previous history of malignancy of pelvic organs or surgical resection of pelvic organs;\n4. Patients those who are diagnosed with other malignancies.;\n5. Patients those who had received pelvic radiotherapy or major pelvic operation.\n6. Pregnancy status;\n7. Any other conditions that the researcher considers to be excluded from this study","FEMALE","55 Years","75 Years",{"count":69,"type":70},58,"ESTIMATED","INTERVENTIONAL",[73],"NA","To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectomy(SRC) with OIN.",[76,77,78,79,80],"Urinary Bladder Neoplasms","Woman","Sexual Dysfunction, Physiological","Treatment Outcome","Urinary Incontinence",[82],"Bladder cancer, Female, Pelvic organ preserving-radical cystectomy, Radical cystectomy, Orthotopic ileal neobladder","NOT_YET_RECRUITING","2022-04-12",{"date":86,"type":87},"2022-04-13","ACTUAL",{"date":89,"type":70},"2022-04",{"date":91,"type":70},"2028-04-01",{"name":5,"class":6},1]