[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100385501":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":212,"collaborators":215,"id":218,"slug":219,"hasResults":220,"nctId":221,"briefTitle":222,"officialTitle":223,"acronym":224,"eligibilityCriteria":225,"healthyVolunteers":220,"sex":226,"minAge":227,"maxAge":228,"enrollmentInfo":229,"targetDuration":24,"studyType":232,"phases":233,"briefSummary":235,"conditions":236,"keywords":24,"overallStatus":242,"whyStopped":24,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":247,"completionDateStruct":249,"leadSponsor":251,"locationsCount":252},{"fullName":5,"class":6},"KU Leuven","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"HTM plus UPP","EXPERIMENTAL","Urinary proteomic profiling administered on top of home blood pressure telemonitoring and guideline-endorsed non-pharmacological and pharmacological management of risk factors",[13],"Diagnostic Test: In-vitro urinary diagnostic test",{"label":15,"type":6,"description":16,"interventionNames":17},"HTM alone","Home blood pressure telemonitoring administered on top of non-pharmacological and pharmacological management of risk factors",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DIAGNOSTIC_TEST","In-vitro urinary diagnostic test","Urinary proteomic profiling (UPP) using established multidimensional urinary markers for progression to CKD (CKD273), left ventricular dysfunction (HF1 and HF2) and coronary heart disease (CAD238 and ACSP75) - in-vitro test certified in Germany and by extension in the EU (DE\u002FCA09\u002F0829\u002FIVD\u002F001, DE\u002FCA09\u002F0829\u002FIVD\u002F005).",[15,9],null,[26],{"name":27,"affiliation":28,"role":29},"Lutgarde Thijs, MSc","University of Leuven","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},"Jan A Staessen, MD, PhD","CONTACT","+32 47 632 4928","jan.staessen@med.kuleuven.be",{"name":37,"role":33,"phone":38,"phoneExt":24,"email":39},"Zen-Yu Zhang, MD, PhD","+32 16 34 7104","zhenyu.zhang@med.kuleuven.be",[41,53,62,71,87,98,109,125,146,161,176,196],{"facility":42,"status":24,"city":43,"state":24,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":24},"European Kidney Health Aliance","Brussels","1000","Belgium","BE",{"type":48,"coordinates":49},"Point",[50,51],4.34878,50.85045,{"lat":51,"lon":50},{"facility":54,"status":24,"city":55,"state":24,"zip":56,"country":45,"countryCode":46,"cosmosGeoPoint":57,"geoPoint":61,"contacts":24},"Diabetes 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AG","Hanover","D-30659","Germany","DE",{"type":48,"coordinates":94},[95,96],9.73322,52.37052,{"lat":96,"lon":95},{"facility":99,"status":24,"city":100,"state":24,"zip":101,"country":102,"countryCode":103,"cosmosGeoPoint":104,"geoPoint":108,"contacts":24},"Biomedical Research Foundation of the Academy of Athens","Athens","115 27","Greece","GR",{"type":48,"coordinates":105},[106,107],23.72784,37.98376,{"lat":107,"lon":106},{"facility":110,"status":24,"city":111,"state":24,"zip":112,"country":113,"countryCode":114,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"Department of Internal Medicine, Faculty of Clinical Sciences, College of Health Sciences, University of Abuja","Abuja","NCT Airport Road","Nigeria","NG",{"type":48,"coordinates":116},[117,118],7.49508,9.05785,{"lat":118,"lon":117},[121],{"name":122,"role":33,"phone":123,"phoneExt":24,"email":124},"Augustine N Odili, MD, PhD","+234 803 395 4983","odilimercy@yahoo.com",{"facility":126,"status":24,"city":127,"state":24,"zip":128,"country":129,"countryCode":130,"cosmosGeoPoint":131,"geoPoint":135,"contacts":136},"Department of Hypertension, Medical University of Gdańsk","Gdansk","80-214","Poland","PL",{"type":48,"coordinates":132},[133,134],18.64912,54.35227,{"lat":134,"lon":133},[137,140,143],{"name":138,"role":33,"phone":24,"phoneExt":24,"email":139},"Krzysztof Narkiewicz, MD, PhD","krzysztof.narkiewicz@gumed.edu.pl",{"name":141,"role":33,"phone":142,"phoneExt":24,"email":24},"Mariana Smoluchowskiego","+58 584 44 40",{"name":144,"role":145,"phone":24,"phoneExt":24,"email":24},"Natasza Gilis-Malinowska","SUB_INVESTIGATOR",{"facility":147,"status":24,"city":148,"state":24,"zip":24,"country":129,"countryCode":130,"cosmosGeoPoint":149,"geoPoint":153,"contacts":154},"First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College","Krakow",{"type":48,"coordinates":150},[151,152],19.93658,50.06143,{"lat":152,"lon":151},[155,159],{"name":156,"role":33,"phone":157,"phoneExt":24,"email":158},"Marek Raizer, MD, PhD","+4812 4002150","marek.raizer@uj.edu.pl",{"name":160,"role":145,"phone":24,"phoneExt":24,"email":24},"Katarzyna Stolarz-Skrzypek, MD, PhD",{"facility":162,"status":24,"city":163,"state":24,"zip":44,"country":164,"countryCode":165,"cosmosGeoPoint":166,"geoPoint":170,"contacts":171},"Department of Internal Medicine, Division of Hypertension, University Medical Centre Ljubljana","Ljubljana","Slovenia","SI",{"type":48,"coordinates":167},[168,169],14.50513,46.05108,{"lat":169,"lon":168},[172],{"name":173,"role":33,"phone":174,"phoneExt":24,"email":175},"Jana Brguljan Hitij, MD, PhD","+386 1 522 50 50","jana.brguljan-hitij@guest.arnes.si",{"facility":177,"status":24,"city":178,"state":24,"zip":179,"country":180,"countryCode":181,"cosmosGeoPoint":182,"geoPoint":186,"contacts":187},"Hypertension in Africa Research Team, Medical Research Council Unit for Hypertension and Cardiovascular Disease, North-West University","Potchefstroom","2520","South Africa","ZA",{"type":48,"coordinates":183},[184,185],27.1,-26.71667,{"lat":185,"lon":184},[188,192,194],{"name":189,"role":33,"phone":190,"phoneExt":24,"email":191},"Alta Schutte, MD, PhD","+27 18 299 1111","alta.schutte@nwu.ac.za",{"name":193,"role":145,"phone":24,"phoneExt":24,"email":24},"Carina Mels, MD, PhD",{"name":195,"role":145,"phone":24,"phoneExt":24,"email":24},"Gontse Mokwatsi, MD, PhD",{"facility":197,"status":24,"city":198,"state":24,"zip":199,"country":200,"countryCode":201,"cosmosGeoPoint":202,"geoPoint":206,"contacts":207},"Centro de Nefrología and Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República","Montevideo","11600","Uruguay","UY",{"type":48,"coordinates":203},[204,205],-56.18816,-34.90328,{"lat":205,"lon":204},[208],{"name":209,"role":33,"phone":210,"phoneExt":24,"email":211},"José Boggia, MD, PhD","+598 2480 98 50","ppboggia@gmail.com",{"type":29,"investigatorFullName":213,"investigatorTitle":214,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Jan A. Staessen","Professor of Medicine",[216],{"name":63,"class":217},"UNKNOWN","100385501","urinary-proteomics-combined-with-home-blood-pressure-telemonitoring-for-health-care-reform-100385501",false,"NCT04299529","Urinary Proteomics Combined With Home Blood Pressure Telemonitoring for Health Care Reform","Urinary Proteomics Combined With Home Blood Pressure Telemonitoring for Health Care Reform: a Randomised Controlled Trial","UPRIGHT-HTM","Inclusion Criteria:\n\n* Patients must have at least three additional guideline-defined risk factors, preferably including hypertension, type 2 diabetes mellitus (T2DM), or both;\n* Patients should be willing patients to engage for the duration of the study in home blood pressure telemonitoring (1 reading per day);\n* Patients must have an email address and internet access via smartphone, tablet, or laptop or desktop computer;\n* Patients should comply with the study protocol during the run-in phase.\n\nExclusion Criteria:\n\n* Type 1 diabetes mellitus;\n* Absence of a practicable echocardiographic window;\n* Previous or concurrent severe cardiovascular or non-cardiovascular disease;\n* Cancer within 5 years of enrolment;\n* Suspected substance abuse;\n* Psychiatric illness;\n* Use of nephrotoxic drugs;\n* Particpation in another clinical study.","ALL","55 Years","75 Years",{"count":230,"type":231},1000,"ESTIMATED","INTERVENTIONAL",[234],"NA","UPRIGHT-HTM will compare risk stratification, treatment efficiency and health economic outcomes of a diagnostic approach based on home blood pressure telemonitoring combined with urinary proteomic profiling with home blood pressure telemonitoring alone",[237,238,239,240,241],"Protein Deregulation","Blood Pressure","Health Care Utilization","Cost Effectiveness","Patient Empowerment","NOT_YET_RECRUITING","2020-03-05",{"date":245,"type":246},"2020-03-06","ACTUAL",{"date":248,"type":231},"2020-04-01",{"date":250,"type":231},"2026-07-31",{"name":5,"class":6},12]