[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494458":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":18,"locations":28,"responsibleParty":45,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":49,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"patient with spinal dysraphism",null,[12],"Other: Individualisation of uronephrological complications risk factors",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"Individualisation of uronephrological complications risk factors","description of pelvic disorders in terms of clinical presentation, electrophysiology\u002Furodynamics\u002Fanorectal manometry patterns, urethrocystography\u002Furinary ultrasound\u002Fdefecography results and urinary complications (infections, vesicoureteral reflux), depending on the dysraphim's type and level of injury and to correlate these parameters to the uronephrological risk factors and complications recorded.",[9],[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Maelys Teng, MD, MSc","CONTACT","0156017954","maelys.teng@aphp.fr",{"name":25,"role":21,"phone":22,"phoneExt":26,"email":27},"Claire Hentzen, MD, MSc","+33","claire.hentzen@aphp.fr",[29],{"facility":30,"status":31,"city":32,"state":10,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Tenon hospital","RECRUITING","Paris","75020","France","FR",{"type":37,"coordinates":38},"Point",[39,40],2.3488,48.85341,{"lat":40,"lon":39},[43,44],{"name":20,"role":21,"phone":22,"phoneExt":26,"email":23},{"name":25,"role":21,"phone":22,"phoneExt":26,"email":27},{"type":46,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100494458","uronephrological-complications-risk-factors-in-spinal-dysraphism-100494458",false,"NCT05718440","Uronephrological Complications Risk Factors in Spinal Dysraphism","Individualisation of Uronephrological Complications Risk Factors in Spinal Dysraphism","RUD","Inclusion Criteria:\n\n* men and women over 18 years old with spinal dysraphism,\n* urinary and\u002For bowel and\u002For sexual dysfunction,\n* evaluated in a one day consultation in a neuro-urology department.\n* Informed consent is required from the patient or his tutor\u002Fcurator if he is under legal protection\n\nExclusion Criteria:\n\n* language barrier with non-understanding of French language,\n* other neurologic pathologies except syringomyelia, Chiari malformation or hydrocephalus who are often associated to spinal dysraphism.","ALL","18 Years",{"count":58,"type":59},200,"ESTIMATED","OBSERVATIONAL","Spinal dysraphism consist of congenital malformations resulting of abnormalities in the formation of neural tube and\u002For surrounding structures during embryogenesis. The aim of this study is to assess if there are specific clinical and paraclinical patterns of pelvic (urinary, bowel, sexual) disorders depending on the dysraphism's type and level of injury.\n\nThis description will help to determine a prognosis on symptoms and the risk of complication depending on the dysraphism's type and level of injury. It will provide targeted evaluation and cares: identifying patients who will be at risk of complications and needing acute monitoring or preventing cares on the symptoms' onset.\n\nPelvic disorders have an important impact on morbi-mortality (urinary dysfunction is the first cause of mortality in adults by renal failure or infection) and also on patients' quality of life.",[63],"Spinal Dysraphism",[65,66,67,68,69,70],"spinal dysraphism","uronephrological complications","risk factors","urinary dysfunction","bowel dysfunction","sexual dysfunction","2024-04-11",{"date":73,"type":74},"2024-04-12","ACTUAL",{"date":76,"type":74},"2023-11-06",{"date":78,"type":59},"2028-11",{"name":5,"class":6},1]