[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100547150":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":19,"locations":20,"responsibleParty":46,"collaborators":19,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":19,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":19,"enrollmentInfo":58,"targetDuration":19,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":70,"whyStopped":19,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University of Manchester","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CardioPulmonary Exercise Testing","EXPERIMENTAL","All patients included in the study will perform CardioPulmonary Exercise Testing prior to surgery",[13],"Diagnostic Test: CardioPulmonary Exercise Testing",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DIAGNOSTIC_TEST","CardioPulmonary Exercise Testing using an arm ergometer prior to surgery",[9],null,[21],{"facility":5,"status":19,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Manchester","Greater Manchester","M13 9PL","United Kingdom","UK",{"type":28,"coordinates":29},"Point",[30,31],-2.23743,53.48095,{"lat":31,"lon":30},[34,38,41,43],{"name":35,"role":36,"phone":19,"phoneExt":19,"email":37},"Mr Jonathan Ghosh","CONTACT","Jonathan.Ghosh@manchester.ac.uk",{"name":39,"role":40,"phone":19,"phoneExt":19,"email":19},"Adam Haque, MBChB, PGCert, MSc, PhD, MRCS","SUB_INVESTIGATOR",{"name":42,"role":40,"phone":19,"phoneExt":19,"email":19},"Stacie Hodge, MBChB, BsC, MRCS",{"name":44,"role":45,"phone":19,"phoneExt":19,"email":19},"Jonathan Ghosh, MBChB MRCS MD MA FRCS","PRINCIPAL_INVESTIGATOR",{"type":45,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Jonathan Ghosh","Honorary Reader Cardiovascular Sciences, Consultant and Clinical Director","100547150","use-of-cpetarm-for-risk-stratification-of-patients-with-clti-100547150",false,"NCT06404229","Use of CPETarm for Risk Stratification of Patients With CLTI","Novel Use of Bedside Arm Ergometry CardioPulmonary Exercise Tests for the Risk Stratification of Patients With Chronic Limb-threatening Ischaemia: A Feasibility Trial","Inclusion Criteria:\n\n* Ability and willingness to give written informed consent\n* Diagnosis of chronic limb threatening ischaemia, undergoing one of the following procedures: Infra inguinal bypass, Extra anatomical bypass, Common femoral endarterectomy, Endovascular treatment, Primary amputation\n\nExclusion Criteria:\n\n* Patients with active medical conditions deemed an absolute contraindication for undertaking CPET\n* Ongoing evaluation for coronary artery disease (e.g awaiting stress test or cardiac catheterisation or requiring the up titration of anti anginal medications)\n* Active arrthymic requiring the initiation or up titration of an anti arrthymic medication\n* Active congestive cardiac failure requiring the initiation or up titration of diuretic therapy.\n* Severe cardiac valvular stenosis\n* Physical disability precluding ability to perform CPETarm\n* Psychiatric disorder or dementia precluding them from consenting for research and\u002For undertaking testing and\u002For follow up","ALL","18 Years",{"count":59,"type":60},120,"ESTIMATED","INTERVENTIONAL",[63],"NA","This is a prospective cohort study of patients undergoing surgery for chronic limb threatening ischaemia. Prior to surgery, patients will undergo CardioPulmonary Exercise testing (CPET) using an arm ergometer. Feasibility outcome measures will be recorded at testing and participants will be followed up for a period of up to 5 years to obtain clinical outcome measures.",[66,67],"Chronic Limb-Threatening Ischemia","Surgery-Complications",[9,69],"Risk Stratification","NOT_YET_RECRUITING","2024-05-03",{"date":73,"type":74},"2024-05-08","ACTUAL",{"date":76,"type":60},"2024-05-28",{"date":78,"type":60},"2030-04-28",{"name":5,"class":6},1]