[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553784":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":7,"responsibleParty":18,"collaborators":7,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":27,"acronym":7,"eligibilityCriteria":28,"healthyVolunteers":29,"sex":30,"minAge":31,"maxAge":32,"enrollmentInfo":33,"targetDuration":7,"studyType":36,"phases":7,"briefSummary":37,"conditions":38,"keywords":7,"overallStatus":41,"whyStopped":7,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":7},{"fullName":5,"class":6},"Los Angeles General Medical Center","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"sevoflurane","No intervention",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"Jody Chou, MD, MPH","CONTACT","949-310-7024","cchou@dhs.lacounty.gov",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Jody Chou","Physician Specialist","100553784","use-of-sevoflurane-to-test-concept-of-cognitive-reserve-100553784",false,"NCT06490588","Use of Sevoflurane to Test Concept of Cognitive Reserve","The Use of Sevoflurane to Test the Concept of Intra-individual Variability in Bispectral Index Monitor and Cognitive Reserve by Examining Time to Emergence and Recovery","Inclusion Criteria:\n\n* \\- Minimal completion of high-school education\n* Adult patient \\\u003C 85 years of age\n* No prior known history of cognitive\u002Fbrain disease\n* ASA class I-II\n* Undergoing general anesthesia with sevoflurane for maintenance anesthesia\n* Same-day surgery\n* Elective procedures\n* No prior history of cardiac disease\n\nExclusion Criteria:\n\n* \\- History of chronic pain\n* Perioperative use of anesthetic agents other than propofol, fentanyl, dilaudid, and sevoflurane\n* History of alcohol\u002Fsubstance druge abuse\n* Psychiatric history\n* Morbid history\n* History of OSA, stroke, or TIA\n* Blindness\n* Deafness",true,"ALL","18 Years","90 Years",{"count":34,"type":35},70,"ESTIMATED","OBSERVATIONAL","Previous pilot study had demonstrated a correlation between cognitive reserve and BIS variability during steady state of anesthesia. This study, we intend to evaluate the association between BIS variability and emergence and recovery time from anesthesia.",[39,40],"Cognitive Reserve","BIS","NOT_YET_RECRUITING","2024-06-28",{"date":44,"type":45},"2024-07-08","ACTUAL",{"date":47,"type":35},"2024-09",{"date":49,"type":35},"2026-09",{"name":5,"class":6}]