[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563927":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":43,"responsibleParty":57,"collaborators":59,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":25,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":72},{"fullName":5,"class":6},"Hospital General de Mexicali","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","This group will receive 100 mEq of sodium bicarbonate diluted in one liter of saline solution, administered at a rate of 100 ml\u002Fh, with the goal of maintaining a urinary pH greater than 6.5.",[13],"Drug: Sodium bicarbonate",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","ACTIVE_COMPARATOR","This group will be manage with the usual care that is given to patients with heat stroke in this hospital.",[19],"Other: No intervention",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DRUG","Sodium bicarbonate",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"No intervention","The usual management for heat stroke will be given to this group",[15],[15],[32],{"name":33,"affiliation":5,"role":34},"Hiram J Jaramillo Ramirez, MD","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Joaquin Cordova Erberk, MD","CONTACT","+52 653 132 0309","joaquincerberk@gmail.com",{"name":33,"role":38,"phone":39,"phoneExt":25,"email":42},"grupoinvestigacionmedica@gmail.com",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":25},"RECRUITING","Mexicali","Estado de Baja California","21000","Mexico","MX",{"type":52,"coordinates":53},"Point",[54,55],-115.45446,32.62781,{"lat":55,"lon":54},{"type":58,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[60],{"name":61,"class":6},"Universidad Autonoma de Baja California","100563927","use-of-sodium-bicarbonate-as-prophylaxis-for-kidney-damage-in-patients-with-heatstroke-100563927",false,"NCT06622525","Use of Sodium Bicarbonate as Prophylaxis for Kidney Damage in Patients With Heatstroke","Inclusion Criteria:\n\n* Admitted to the General Hospital of Mexicali with the diagnosis of heat stroke.\n* Meeting the operational definition (exposure to heat, body temperature at admission greater than 40 degrees Celsius).\n* CPK level greater than 1000 U\u002FL.\n* Having informed consent from the patient or the legally responsible adult.\n\nExclusion Criteria:\n\n* Exclusion of the heat stroke diagnosis during their evaluation.\n* Lack of serum creatinine levels at the time of admission to the protocol.",true,"ALL","18 Years",{"count":72,"type":73},1,"ESTIMATED","INTERVENTIONAL",[76],"NA","This study protocol aims to prevent the need for renal replacement therapy in patients with rhabdomyolysis secondary to heatstroke. It is based on previous studies showing that bicarbonate infusion reduces renal failure in similar contexts. The intervention will be conducted at the General Hospital of Mexicali during the summer, targeting the prevention of renal failure and reducing the necessity for renal replacement therapy.",[79,80,81],"Heat Stroke","Acute Kidney Injury","Acute Kidney Injury Due to Hypovolaemia","2024-09-30",{"date":84,"type":85},"2024-10-02","ACTUAL",{"date":87,"type":85},"2024-05-01",{"date":89,"type":73},"2025-10-01",{"name":5,"class":6}]