[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635439":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":42,"responsibleParty":58,"collaborators":24,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":24,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":24,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":84,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Hitit University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"M-TAPA Group","ACTIVE_COMPARATOR","M-TAPA Group:\n\nPatients receiving ultrasound-guided bilateral Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) using 20 ml of 0.25% bupivacaine per side, applied at the 10th rib level beneath the costochondral perichondrium after surgery while under anesthesia.",[13],"Procedure: M-TAPA Group",{"label":15,"type":10,"description":16,"interventionNames":17},"RIFPB Group","RIFPB Group:\n\nPatients receiving ultrasound-guided bilateral Recto-Intercostal Fascial Plane Block (RIFPB) using 20 ml of 0.25% bupivacaine per side, injected into the interfascial plane between the rectus abdominis muscle and the 6th-7th costal cartilages just below the xiphoid process, applied after surgery while under anesthesia.",[18],"Procedure: RIFPB Group",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Patients receiving ultrasound-guided bilateral Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) using 20 ml of 0.25% bupivacaine per side, applied at the 10th rib level beneath the costochondral perichondrium after surgery while under anesthesia.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Patients receiving ultrasound-guided bilateral Recto-Intercostal Fascial Plane Block (RIFPB) using 20 ml of 0.25% bupivacaine per side, injected into the interfascial plane between the rectus abdominis muscle and the 6th-7th costal cartilages just below the xiphoid process, applied after surgery while under anesthesia.",[15],[29],{"name":30,"affiliation":5,"role":31},"Guvenc Dogan, MD","STUDY_CHAIR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":24,"email":37},"Hakan Akel, MD","CONTACT","+905442094827","drhakanakel@gmail.com",{"name":39,"role":35,"phone":40,"phoneExt":24,"email":41},"Alperen KISA, MD","+905072322428","alperenkisa@hotmail.com.tr",[43],{"facility":5,"status":44,"city":45,"state":24,"zip":46,"country":47,"countryCode":24,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Çorum","19100","Turkey (Türkiye)",{"type":49,"coordinates":50},"Point",[51,52],34.95333,40.54889,{"lat":52,"lon":51},[55],{"name":30,"role":35,"phone":56,"phoneExt":24,"email":57},"+905324025208","guvencdogan@gmail.com",{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Hakan AKEL","Principal Investigator","100635439","usg-guided-tapa-vs-rifb-block-for-postoperative-analgesia-in-laparoscopic-cholecystectomy-100635439",false,"NCT07552701","USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy","Comparison of Ultrasonography-Guided the Postoperative Analgesic Efficacy of Perichondrial Approach Modified Thoracoabdominal Nerve Block and Recto-Intercostal Fascial Plan Block in Patients Who Underwent Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n* Age 18-65 years\n* ASA physical classification I-II\n* BMI \\\u003C 35 kg\u002Fm²\n* Scheduled for elective laparoscopic cholecystectomy due to cholelithiasis\n* Able to use and understand the NRS pain scoring system\n* Able to use and understand the QoR-15 scale\n* Able to communicate in Turkish\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* BMI \\> 35 kg\u002Fm²\n* ASA physical classification III-V\n* Age \\\u003C 18 or \\> 65 years\n* Allergy to local anesthetics or study analgesics\n* Pregnancy or breastfeeding\n* Inability to use or understand the NRS pain scoring system or QoR-15 scale\n* Inability to communicate in Turkish\n* Uncontrolled anxiety disorder\n* Alcohol or drug dependency\n* Neuromuscular or peripheral nerve disease\n* High-dose opioid use within 3 days prior to surgery\n* Widespread chronic pain\n* Diabetes mellitus\n* Hepatic or renal insufficiency\n* Coagulation disorders or anticoagulant use\n* Infection at the block needle insertion site\n* Concurrent second surgical procedure alongside laparoscopic cholecystectomy\n* Previous abdominal surgery or trauma history\n* Conversion from laparoscopic to open surgery\n* Technical problems with the PCA device\n* NRS score \\> 7 for four consecutive hours despite multimodal analgesia\n* Planned postoperative non-extubation\n* Termination of surgery before completion for any reason","ALL","18 Years","65 Years",{"count":73,"type":74},70,"ESTIMATED","INTERVENTIONAL",[77],"NA","Laparoscopic cholecystectomy (LC) can cause moderate-to-severe postoperative pain from visceral, referred shoulder, and incisional sources. Multimodal analgesia is recommended, but opioids carry significant side effects. Ultrasound-guided interfascial plane blocks offer a safe alternative. The Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) blocks T5-T12 dermatomes, while the Recto-Intercostal Fascial Plane Block (RIFPB) provides sensory blockade across the upper anterolateral abdomen. This study compares the postoperative analgesic efficacy of bilateral M-TAPA versus bilateral RIFPB in patients undergoing LC.",[80,81,82,83],"Postoperative Pain","Acute Cholecystitis","Cholelithiasis","Postoperative Nausea and Vomiting",[85,86,87],"Laparoscopic Cholecystectomy","Transversus abdominis Plane Block","Rectus-intercostalis facial plane block","2026-04-20",{"date":90,"type":91},"2026-04-27","ACTUAL",{"date":93,"type":91},"2025-03-16",{"date":95,"type":74},"2026-05-30",{"name":5,"class":6},1]