[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623695":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":29,"centralContacts":33,"locations":43,"responsibleParty":142,"collaborators":24,"id":144,"slug":145,"hasResults":146,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":24,"eligibilityCriteria":150,"healthyVolunteers":146,"sex":151,"minAge":152,"maxAge":24,"enrollmentInfo":153,"targetDuration":24,"studyType":156,"phases":157,"briefSummary":159,"conditions":160,"keywords":163,"overallStatus":46,"whyStopped":24,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":174},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"High risk for recurrent Venous Thromboembolism\u002FVTE","EXPERIMENTAL","Participants with a ≤5% chance of Venous Thromboembolism\u002FVTE according to the model will be designated \"low risk\" for the purposes of the study; all other participants will be considered \"high risk.",[13,14],"Diagnostic Test: MSK-ACCESS","Diagnostic Test: ctDNA\u002FVTE Risk Score:",{"label":16,"type":10,"description":11,"interventionNames":17},"Low-risk for recurrent Venous Thromboembolism\u002FVTE",[13,14],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DIAGNOSTIC_TEST","MSK-ACCESS","MSK-ACCESS is a ctDNA sequencing assay",[9,16],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"ctDNA\u002FVTE Risk Score:","Machine learning Venous Thromboembolism\u002FVTE risk score mode",[9,16],[30],{"name":31,"affiliation":5,"role":32},"Justine Jee, MD, PhD","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Justin Jee, MD, PhD","CONTACT","646-608-4409","jeej@mskcc.org",{"name":40,"role":36,"phone":41,"phoneExt":24,"email":42},"Jeffrey Zwicker, MD","646-608-3723","zwickerj@mskcc.org",[44,60,71,82,94,105,115,126],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Memorial Sloan Kettering Cancer Center Basking Ridge (All Protocol Activities)","RECRUITING","Basking Ridge","New Jersey","07920","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-74.54932,40.70621,{"lat":56,"lon":55},[59],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":24},{"facility":61,"status":46,"city":62,"state":48,"zip":63,"country":50,"countryCode":51,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Memorial Sloan Kettering Monmouth (All Protocol Activities)","Middletown","07748",{"type":53,"coordinates":65},[66,67],-74.11709,40.39428,{"lat":67,"lon":66},[70],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":24},{"facility":72,"status":46,"city":73,"state":48,"zip":74,"country":50,"countryCode":51,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Memorial Sloan Kettering Bergen (All Protocol Activities)","Montvale","07645",{"type":53,"coordinates":76},[77,78],-74.02292,41.04676,{"lat":78,"lon":77},[81],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":24},{"facility":83,"status":46,"city":84,"state":85,"zip":86,"country":50,"countryCode":51,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities)","Commack","New York","11725",{"type":53,"coordinates":88},[89,90],-73.29289,40.84288,{"lat":90,"lon":89},[93],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":24},{"facility":95,"status":46,"city":96,"state":85,"zip":97,"country":50,"countryCode":51,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Memorial Sloan Kettering Westchester (All Protocol Activities)","Harrison","10604",{"type":53,"coordinates":99},[100,101],-73.71263,40.96899,{"lat":101,"lon":100},[104],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":24},{"facility":106,"status":46,"city":85,"state":85,"zip":107,"country":50,"countryCode":51,"cosmosGeoPoint":108,"geoPoint":112,"contacts":113},"Memorial Sloan Kettering Cancer Center (All Protocol Activites)","10065",{"type":53,"coordinates":109},[110,111],-74.00597,40.71427,{"lat":111,"lon":110},[114],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":24},{"facility":116,"status":46,"city":117,"state":85,"zip":118,"country":50,"countryCode":51,"cosmosGeoPoint":119,"geoPoint":123,"contacts":124},"Memorial Sloan Kettering Nassau (All protocol activities)","Rockville Centre","11553",{"type":53,"coordinates":120},[121,122],-73.64124,40.65871,{"lat":122,"lon":121},[125],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":24},{"facility":127,"status":128,"city":129,"state":24,"zip":130,"country":131,"countryCode":132,"cosmosGeoPoint":133,"geoPoint":137,"contacts":138},"Royal North Shore Hospital, Australia","NOT_YET_RECRUITING","Sydney","2065","Australia","AU",{"type":53,"coordinates":134},[135,136],151.20732,-33.86785,{"lat":136,"lon":135},[139],{"name":140,"role":36,"phone":141,"phoneExt":24,"email":24},"Adrian Lee, MBBS, FRACP PhD","02 8037 4100",{"type":143,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100623695","using-a-blood-test-and-software-tool-to-guide-treatment-for-venous-thromboembolism-100623695",false,"NCT07399977","Using a Blood Test and Software Tool to Guide Treatment for Venous Thromboembolism","A Nonrandomized Trial Using DNA Liquid Biopsies to Guide Anticoagulation For Patients With Cancer-Associated Thromboembolism","Inclusion Criteria:\n\n* Age ≥ 18 with a history of cancer-associated VTE (objectively confirmed symptomatic or incidental\u002Funsuspected proximal lower-limb DVT, symptomatic pulmonary embolism \\[PE\\] or incidental PE in a segmental or more proximal pulmonary artery) and completion of between 3 and 12 months of anticoagulation with enoxaparin, dalteparin,rivaroxaban, or apixaban without current VTE-related symptoms (imaging to confirm resolution not required).\n\nDiagnosis of DVT requires evidence of one or more filling defects at compression ultrasonography, venography, CT venography, or MR venography involving at least the popliteal or more proximal veins.\n\nDiagnosis of PE requires an intraluminal filling defect in segmental or more proximal arteries.\n\n* Diagnosis of one of the following solid tumors in either advanced (i.e. unresectable) stage or receiving systemic anticancer treatment within six weeks of enrollment (maintenance therapy included):\n\n  * breast cancer regardless of cytotoxic-chemotherapy status\n  * hepatobiliary cancer regardless of cytotoxic-chemotherapy status\n  * prostate cancer regardless of cytotoxic-chemotherapy status\n  * non-small cell lung cancer with cytotoxic-chemotherapy received within 30 days\n  * pancreatic cancer with cytotoxic-chemotherapy received within 30 days\n  * bladder cancer with cytotoxic-chemotherapy received within 30 days\n* Signed and dated informed consent by study participant\u002FLegally Authorized Representative (LAR).\n\nExclusion Criteria:\n\n* Contraindication to ongoing anticoagulation\n* Contraindication to discontinuation of anticoagulation (examples include but not limited to: known antiphospholipid syndrome or factor V leiden, active arterial thrombus, catheter-associated thrombus, on anticoagulation for atrial fibrillation or other non-oncologic reasons)\n* History of major bleeding in the last six months (major bleeding defined as fatal bleeding, and\u002For symptomatic bleeding in a critical area or organ, such as intracranial, intraspinal, intraocular, retroperitoneal, intra-articular or pericardial, or intramuscular with compartment syndrome; bleeding that necessitates acute surgical intervention; bleeding causing a fall in hemoglobin levels of 1.24 mmol\u002FL (2 g\u002FdL or greater) or more; or bleeding leading to a transfusion of 2 U or more of whole blood or red cells).\n* Known diagnosis of disseminated intravascular coagulation (DIC)\n* Suspicion for tumor thrombus on the imaging leading to original diagnosis of VTE\n* Enrolled in hospice care\n* Currently has inferior vena cava (IVC) filter\n* Diagnosis of an active hematologic malignancy","ALL","18 Years",{"count":154,"type":155},259,"ESTIMATED","INTERVENTIONAL",[158],"NA","The purpose of this study is to find out whether a software tool, ctDNA\u002FVTE (Venous Thromboembolism) risk score model, is an effective way to predict the likelihood of VTE coming back in people who have received anticoagulant treatment.",[161,162],"Venous Thromboembolism","Deep Venous Thrombosis",[161,162,164,5],"25-095","2026-05-04",{"date":167,"type":168},"2026-05-05","ACTUAL",{"date":170,"type":168},"2026-01-30",{"date":172,"type":155},"2030-01-30",{"name":5,"class":6},8]