[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528138":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":77,"collaborators":80,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":18,"eligibilityCriteria":95,"healthyVolunteers":96,"sex":97,"minAge":98,"maxAge":99,"enrollmentInfo":100,"targetDuration":18,"studyType":103,"phases":104,"briefSummary":106,"conditions":107,"keywords":111,"overallStatus":40,"whyStopped":18,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},{"fullName":5,"class":6},"University of Toronto","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention to address late talking","EXPERIMENTAL","half the participants receive an intervention program addressing late talking. The intervention is comprised of adult learning (to teach parents) and direct support for children who are late talkers. The intervention occurs over 6 to 8 weeks and is designed to improve grammar, vocabulary, and functional communication",[13],"Behavioral: Intervention to address late talking",{"label":15,"type":16,"description":17,"interventionNames":18},"Waitlist controls","NO_INTERVENTION","half the participants are waitlist controls who receive intervention at a later date, after the study has ended",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","this intervention is designed to support both speech and language development in children who are toddlers. Given the age group of children their parents are part of the intervention program. Importantly the frequency of the intervention can range from once to twice per week, with timing also designed to complement the particular agency",[9],[25],{"name":26,"affiliation":5,"role":27},"Karla N Washington, PhD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":18,"email":32},"CONTACT","416-978-6499","karla.washington@utoronto.ca",{"name":34,"role":30,"phone":35,"phoneExt":18,"email":36},"Nicole Bazzocchi, MhSc","647-239-9330","nicole.bazzocchi@mail.utoronto.ca",[38,60],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Grandview Kids","RECRUITING","Oshawa","Ontario","L1H0C8","Canada","CA",{"type":47,"coordinates":48},"Point",[49,50],-78.84957,43.90012,{"lat":50,"lon":49},[53,57],{"name":54,"role":30,"phone":55,"phoneExt":18,"email":56},"Taryn Eickmeier","1-800-304-6180","Taryn.Eickmeier@grandviewkids.ca",{"name":58,"role":30,"phone":55,"phoneExt":18,"email":59},"Alicia Gibson","Alicia.Gibson@grandviewkids.ca",{"facility":61,"status":40,"city":62,"state":42,"zip":63,"country":44,"countryCode":45,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Speech Specialists","Toronto","M1X0C3",{"type":47,"coordinates":65},[66,67],-79.39864,43.70643,{"lat":67,"lon":66},[70,74],{"name":71,"role":30,"phone":72,"phoneExt":18,"email":73},"Maheen Mas","416-858-4300","maheen@speechspecialists.ca",{"name":75,"role":30,"phone":18,"phoneExt":18,"email":76},"Emily Wood","e.wood@utoronto.ca",{"type":27,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Karla Washington","Associate Professor",[81,83,85,87],{"name":82,"class":6},"Holland Bloorview Kids Rehabilitation Hospital",{"name":84,"class":6},"Children's Hospital Medical Center, Cincinnati",{"name":86,"class":6},"University of Cincinnati",{"name":88,"class":6},"Georgetown University","100528138","using-neuroimaging-and-behavioral-assessments-to-understand-late-talking-100528138",false,"NCT06156865","Using Neuroimaging and Behavioral Assessments to Understand Late Talking","Neuroimaging Reveals Treatment-related Changes in DLD: A Randomized Controlled Trial (Supplement)","Inclusion Criteria:\n\n* child and parent are monolingual\u002Fnative (primarily) English speakers\n* child is enrolled at one of the participating facilities\n* child is recruited via word of mouth, including social media\n* child is between 18 and 30 months of age\n* child does not have any contraindications to magnetic resonance imaging (i.e., intracranial metal implants, claustrophobia)\n* child does not have any uncorrected vision challenges\n\nExclusion Criteria:\n\n* Child does not meet criteria for LT or typical development\n* Standard magnetic resonance imaging exclusion criteria\n* Gestational age less than 37 weeks or greater than 42 weeks\n* Special education placement of child based on ability or behavior",true,"ALL","18 Months","30 Months",{"count":101,"type":102},45,"ESTIMATED","INTERVENTIONAL",[105],"NA","Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder. While effective and early interventions can mitigate the impact of late talking, not enough is known about its neural basis, yet is needed to inform the design of more individualized interventions. This proposed effort uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie learning and late talking, while also considering their association to treatment-related changes in LT.",[108,109,110],"Developmental Language Disorder","Language Delay","Language Development",[112,113,114,115,116,117],"children","late talking","typical development","assessment","intervention","neuroimaging","2026-05-29",{"date":120,"type":121},"2026-06-02","ACTUAL",{"date":123,"type":121},"2024-01-19",{"date":125,"type":102},"2027-06-30",{"name":5,"class":6},2]