[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572342":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":25,"eligibilityCriteria":45,"healthyVolunteers":42,"sex":46,"minAge":47,"maxAge":25,"enrollmentInfo":48,"targetDuration":25,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":60,"whyStopped":25,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":25},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"group A","EXPERIMENTAL","Vaccum Assisted Closure of Wound",[13],"Procedure: Vaccum assisted closure",{"label":15,"type":10,"description":16,"interventionNames":17},"group B","primary closure Closure of Wound",[18],"Procedure: primary wound closure",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Vaccum assisted closure","close skin and SC tissue by vaccum device",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"primary wound closure","close skin and SC tissue by primary closure",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"mahmoud hassan Anwer, resident doctor","CONTACT","+201023796252","ohioclassegx98@gmail.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Mahmoud Hassan Anwar Ali","resident doctor at general surgery department Faculty of Medicine, Assiut University","100572342","using-vaccum-assisted-closure-of-wound-instead-of-primary-closure-as-prophylactic-way-against-burst-abdomen-100572342",false,"NCT06732024","Using Vaccum Assisted Closure of Wound Instead of Primary Closure as Prophylactic Way Against Burst Abdomen","Inclusion Criteria:\n\n* intraabdominal sepsis (wbc:\\>12000,HR\\>90,T\\>38,tachypnea and proven infection) Malnutrition including anaemia and hypoproteinemia Chronic diseases including diabetes and uremia Increased intra abdominal pressure including persistent coughing ,diffuse gaseous distention Smoking Previous abdominal surgery Old age Steroid use\n\noperation : Emergency not elective ones Dirty or contaminated Those involving colostomy and ileostomy that is close to wound\n\nExclusion Criteria:\n\n* Patients having elective surgery Absence of intra abdominal sepsis Negative exploration","ALL","18 Years",{"count":49,"type":50},100,"ESTIMATED","INTERVENTIONAL",[53],"NA","A vacuum-assisted closure (VAC) device also known as negative pressure wound therapy (NPWT), is a medical treatment used to promote wound healing, it involves using a specialized device to apply negative pressure (suction) to a wound, which helps to accelerate the healing process.\n\nBenefits :\n\nImproved Healing: By removing excess fluid and reducing edema, the VAC device promotes faster wound healing and tissue repair.\n\nReduced Risk of Infection: The negative pressure helps to reduce bacterial load and create a more favorable environment for healing.\n\nEnhanced Perfusion: The suction can improve blood flow to the wound area, aiding in the delivery of nutrients and oxygen essential for healing.\n\nGranulation Tissue Formation: The therapy encourages the growth of new tissue (granulation tissue) which fills the wound and supports closure.\n\nOverall, VAC therapy is a valuable tool in modern wound care, particularly for complex or difficult-to-heal wounds. If you or someone you know is considering or using this therapy, it's important to follow the guidance of healthcare professionals to maximize its effectiveness and manage any potential risks.\n\nthe study aim to evaluate patients , identify high risk ones , preparing to close wound of laparotomy with vaccum assisted device instead of primary closure with suturing till patient's general condition improve then delayed primary closure and comparing that to high risk patients who close wound primarily with suturing in terms of rate of burst abdomen …this is a randomized controlled trial",[56],"Burst Abdomen",[58,59],"Vaccum Assisted Closure","primary closure","NOT_YET_RECRUITING","2024-12-10",{"date":63,"type":64},"2024-12-13","ACTUAL",{"date":66,"type":50},"2025-01-01",{"date":68,"type":50},"2026-03-01",{"name":5,"class":6}]