[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100481813":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":35,"responsibleParty":53,"collaborators":55,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":17,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":20,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":38,"whyStopped":20,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Sheffield Children's NHS Foundation Trust","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Diagnostic (PET-MRI)","EXPERIMENTAL","Patients will undergo PET-MRI",[13],"Radiation: PET-MRI",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"RADIATION","PET-MRI","magnetic resonance imaging with positron emission tomography scanning using the tracer 18F-FDG",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Ola Rominyi, MBChB","University of Sheffield","PRINCIPAL_INVESTIGATOR",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"David King, MBChB","CONTACT","0114 2717354","d.king6@nhs.net",{"name":33,"role":29,"phone":30,"phoneExt":20,"email":34},"Keith Pugh, PhD","keith.pugh1@nhs.net",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Sheffield Children's Hospital","RECRUITING","Sheffield","South Yorkshire","S10 1SN","United Kingdom","UK",{"type":45,"coordinates":46},"Point",[47,48],-1.4659,53.38297,{"lat":48,"lon":47},[51],{"name":52,"role":29,"phone":20,"phoneExt":20,"email":20},"Keith Pugh",{"type":54,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[56,59],{"name":57,"class":58},"GE Healthcare","INDUSTRY",{"name":24,"class":6},"100481813","utility-of-pet-mri-in-surveillance-of-paediatric-brain-tumours-100481813",false,"NCT05553899","Utility of PET-MRI in Surveillance of Paediatric Brain Tumours","Utility of PET-MRI in Post-treatment Surveillance of Paediatric Brain Tumours: a Pilot Study","Inclusion Criteria:\n\n* Have a presumptive or histologically confirmed diagnosis of a malignant brain tumour requiring treatment\n* Diagnostic uncertainty about tumour recurrence post-treatment based on conventional MR imaging in the opinion of the MDT\n* Have a life expectancy of at least three months\n* Able to comply with an MRI scan without a general anaesthetic\n\nExclusion Criteria:\n\n* Unable to comply with an MRI scan without a general anaesthetic\n* Diabetes or other causes of hyperglycaemia\n* Pregnancy\n* Patient body habitus above scanner dimensions\n* Standard contra-indication to MRI (eg. pacemaker, non-compatible metallic implants, altered renal function)","ALL","8 Years","18 Years",{"count":71,"type":72},5,"ESTIMATED","INTERVENTIONAL",[75],"NA","This is a pilot project to explore the utility of PET-MRI in the post-treatment surveillance of high-grade gliomas or medulloblastomas in children in our institution.",[78],"Brain Tumor, Pediatric",[80],"Brain Tumor, children, PET, MRI","2026-04-29",{"date":83,"type":84},"2026-05-06","ACTUAL",{"date":86,"type":84},"2024-02-28",{"date":88,"type":72},"2027-06",{"name":5,"class":6},1]