[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100506479":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":32,"locations":38,"responsibleParty":338,"collaborators":10,"id":340,"slug":341,"hasResults":342,"nctId":343,"briefTitle":344,"officialTitle":345,"acronym":346,"eligibilityCriteria":347,"healthyVolunteers":342,"sex":348,"minAge":349,"maxAge":10,"enrollmentInfo":350,"targetDuration":353,"studyType":354,"phases":10,"briefSummary":355,"conditions":356,"keywords":365,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":391,"lastUpdatePostDateStruct":392,"startDateStruct":395,"completionDateStruct":397,"leadSponsor":399,"locationsCount":400},{"fullName":5,"class":6},"UroGen Pharma Ltd.","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Jelmyto",null,"Patients with UTUC treated with Jelmyto",[13],"Drug: Jelmyto (mitomycin) for pyelocalyceal solution",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Jelmyto (mitomycin) for pyelocalyceal solution","The dose of Jelmyto to be instilled is 4 mg per mL via ureteral catheter or a nephrostomy tube, with total instillation volume based on volumetric measurements using pyelography, not to exceed 15 mL (60 mg of mitomycin).\n\nInstill Jelmyto once weekly for six weeks. For patients with a complete response 3 months after Jelmyto initiation, Jelmyto instillations may be administered once a month for a maximum of 11 additional instillations.",[9],[9,21],"UGN-101",[23,27,30],{"name":24,"affiliation":25,"role":26},"Yair Lotan, MD","UT Southwestern Medical Center at Dallas","PRINCIPAL_INVESTIGATOR",{"name":28,"affiliation":29,"role":26},"Adam Feldman, MD","Massachusett's General Hospital",{"name":31,"affiliation":25,"role":26},"Solomon Woldu, MD",[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Michael Louie, MD, MPH, MSc","CONTACT","855-987-6436","registry@urogen.com",[39,57,72,85,98,112,126,140,154,164,177,187,201,215,229,243,255,268,282,297,311,325],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Providence St. Johns Health Center","RECRUITING","Santa Monica","California","90404","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-118.49138,34.01949,{"lat":51,"lon":50},[54],{"name":55,"role":35,"phone":10,"phoneExt":10,"email":56},"Jennifer Linehan, MD","Jennifer.linehan@providence.org",{"facility":58,"status":41,"city":59,"state":60,"zip":61,"country":45,"countryCode":46,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"University of Florida","Gainesville","Florida","32610",{"type":48,"coordinates":63},[64,65],-82.32483,29.65163,{"lat":65,"lon":64},[68],{"name":69,"role":35,"phone":70,"phoneExt":10,"email":71},"Padraic OMalley, MD","352-265-8240","Padraic.O'Malley@urology.ufl.edu",{"facility":73,"status":41,"city":74,"state":60,"zip":75,"country":45,"countryCode":46,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Mount Sinai Medical Center of Florida, Inc.","Miami","33140",{"type":48,"coordinates":77},[78,79],-80.19366,25.77427,{"lat":79,"lon":78},[82],{"name":83,"role":35,"phone":10,"phoneExt":10,"email":84},"Alan Nieder, MD","Alan.Nieder@msmc.com",{"facility":86,"status":41,"city":87,"state":60,"zip":88,"country":45,"countryCode":46,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc.","Tampa","33612",{"type":48,"coordinates":90},[91,92],-82.45843,27.94752,{"lat":92,"lon":91},[95],{"name":96,"role":35,"phone":10,"phoneExt":10,"email":97},"Wade Sexton, MD","Wade.Sexton@moffitt.org",{"facility":99,"status":41,"city":100,"state":101,"zip":102,"country":45,"countryCode":46,"cosmosGeoPoint":103,"geoPoint":107,"contacts":108},"Northwestern University","Chicago","Illinois","60611",{"type":48,"coordinates":104},[105,106],-87.65005,41.85003,{"lat":106,"lon":105},[109],{"name":110,"role":35,"phone":10,"phoneExt":10,"email":111},"Joshua Meeks, MD","joshua.meeks@northwestern.edu",{"facility":113,"status":41,"city":114,"state":115,"zip":116,"country":45,"countryCode":46,"cosmosGeoPoint":117,"geoPoint":121,"contacts":122},"Indiana University","Indianapolis","Indiana","46202",{"type":48,"coordinates":118},[119,120],-86.15804,39.76838,{"lat":120,"lon":119},[123],{"name":124,"role":35,"phone":10,"phoneExt":10,"email":125},"Hristos Kaimakliotis, MD","hkaimakl@iupui.edu",{"facility":127,"status":41,"city":128,"state":129,"zip":130,"country":45,"countryCode":46,"cosmosGeoPoint":131,"geoPoint":135,"contacts":136},"The State University of Iowa","Iowa City","Iowa","52242",{"type":48,"coordinates":132},[133,134],-91.53017,41.66113,{"lat":134,"lon":133},[137],{"name":138,"role":35,"phone":10,"phoneExt":10,"email":139},"Michael ODonnell, MD","michael-odonnell@uiowa.edu",{"facility":141,"status":41,"city":142,"state":143,"zip":144,"country":45,"countryCode":46,"cosmosGeoPoint":145,"geoPoint":149,"contacts":150},"Chesapeake Urology","Baltimore","Maryland","21204",{"type":48,"coordinates":146},[147,148],-76.61219,39.29038,{"lat":148,"lon":147},[151],{"name":152,"role":35,"phone":10,"phoneExt":10,"email":153},"Rian Dickstein, MD","rdickstein@chesuro.com",{"facility":155,"status":41,"city":142,"state":143,"zip":156,"country":45,"countryCode":46,"cosmosGeoPoint":157,"geoPoint":159,"contacts":160},"Johns Hopkins Medical Center","21287",{"type":48,"coordinates":158},[147,148],{"lat":148,"lon":147},[161],{"name":162,"role":35,"phone":163,"phoneExt":10,"email":10},"Nirmish Singla, MD","410-955-6100",{"facility":165,"status":41,"city":166,"state":167,"zip":168,"country":45,"countryCode":46,"cosmosGeoPoint":169,"geoPoint":173,"contacts":174},"Mass General Hospital (MGH)","Boston","Massachusetts","02114",{"type":48,"coordinates":170},[171,172],-71.05977,42.35843,{"lat":172,"lon":171},[175],{"name":28,"role":35,"phone":10,"phoneExt":10,"email":176},"afeldman@mgb.org",{"facility":178,"status":41,"city":166,"state":167,"zip":179,"country":45,"countryCode":46,"cosmosGeoPoint":180,"geoPoint":182,"contacts":183},"The Brigham and Womens Hospital","02115",{"type":48,"coordinates":181},[171,172],{"lat":172,"lon":171},[184],{"name":185,"role":35,"phone":10,"phoneExt":10,"email":186},"Steven Chang, MD","SLCHANG@BWH.HARVARD.EDU",{"facility":188,"status":41,"city":189,"state":190,"zip":191,"country":45,"countryCode":46,"cosmosGeoPoint":192,"geoPoint":196,"contacts":197},"University of Michigan","Ann Arbor","Michigan","48109",{"type":48,"coordinates":193},[194,195],-83.74088,42.27756,{"lat":195,"lon":194},[198],{"name":199,"role":35,"phone":10,"phoneExt":10,"email":200},"Khurshid Ghani, MD","kghani@med.umich.edu",{"facility":202,"status":41,"city":203,"state":204,"zip":205,"country":45,"countryCode":46,"cosmosGeoPoint":206,"geoPoint":210,"contacts":211},"University of Missouri","Columbia","Missouri","65211",{"type":48,"coordinates":207},[208,209],-92.33407,38.95171,{"lat":209,"lon":208},[212],{"name":213,"role":35,"phone":10,"phoneExt":10,"email":214},"Eliza DeFroda, MD","elddmc@health.missouri.edu",{"facility":216,"status":41,"city":217,"state":218,"zip":219,"country":45,"countryCode":46,"cosmosGeoPoint":220,"geoPoint":224,"contacts":225},"Rutgers","New Brunswick","New Jersey","08903",{"type":48,"coordinates":221},[222,223],-74.45182,40.48622,{"lat":223,"lon":222},[226],{"name":227,"role":35,"phone":10,"phoneExt":10,"email":228},"Saum Ghodoussipour, MD","sg1621@cinj.rutgers.edu",{"facility":230,"status":41,"city":231,"state":232,"zip":233,"country":45,"countryCode":46,"cosmosGeoPoint":234,"geoPoint":238,"contacts":239},"The Feinstein Institutes for Medical Research","Lake Success","New York","11042",{"type":48,"coordinates":235},[236,237],-73.71763,40.77066,{"lat":237,"lon":236},[240],{"name":241,"role":35,"phone":10,"phoneExt":10,"email":242},"David Hoenig, MD","dhoenig@northwell.edu",{"facility":244,"status":41,"city":232,"state":232,"zip":245,"country":45,"countryCode":46,"cosmosGeoPoint":246,"geoPoint":250,"contacts":251},"NYU Grossman School of Medicine","10016",{"type":48,"coordinates":247},[248,249],-74.00597,40.71427,{"lat":249,"lon":248},[252],{"name":253,"role":35,"phone":10,"phoneExt":10,"email":254},"Katie Murray, MD","Katie.Murray@nyulangone.org",{"facility":256,"status":41,"city":257,"state":232,"zip":258,"country":45,"countryCode":46,"cosmosGeoPoint":259,"geoPoint":263,"contacts":264},"SUNY Upstate","Syracuse","13210",{"type":48,"coordinates":260},[261,262],-76.14742,43.04812,{"lat":262,"lon":261},[265],{"name":266,"role":35,"phone":10,"phoneExt":10,"email":267},"Joseph Jacob, MD","JacobJ@upstate.edu",{"facility":269,"status":41,"city":270,"state":271,"zip":272,"country":45,"countryCode":46,"cosmosGeoPoint":273,"geoPoint":277,"contacts":278},"The University of North Carolina Chapel Hill","Chapel Hill","North Carolina","27599",{"type":48,"coordinates":274},[275,276],-79.05584,35.9132,{"lat":276,"lon":275},[279],{"name":280,"role":35,"phone":10,"phoneExt":10,"email":281},"Marc Bjurlin, MD","marc_bjurlin@med.unc.edu",{"facility":283,"status":41,"city":284,"state":285,"zip":286,"country":45,"countryCode":46,"cosmosGeoPoint":287,"geoPoint":291,"contacts":292},"Ohio State University","Columbus","Ohio","43202",{"type":48,"coordinates":288},[289,290],-82.99879,39.96118,{"lat":290,"lon":289},[293],{"name":294,"role":35,"phone":295,"phoneExt":10,"email":296},"Ahmad Shabsigh, MD","614-685-4263","Ahmad.Shabsigh@osumc.edu",{"facility":298,"status":41,"city":299,"state":300,"zip":301,"country":45,"countryCode":46,"cosmosGeoPoint":302,"geoPoint":306,"contacts":307},"Medical University of South Carolina","Charleston","South Carolina","29425",{"type":48,"coordinates":303},[304,305],-79.93275,32.77632,{"lat":305,"lon":304},[308],{"name":309,"role":35,"phone":10,"phoneExt":10,"email":310},"Karthik Tanneru, MD","tanneru@musc.edu",{"facility":312,"status":41,"city":313,"state":314,"zip":315,"country":45,"countryCode":46,"cosmosGeoPoint":316,"geoPoint":320,"contacts":321},"UT Southwestern Medical Center","Dallas","Texas","75390",{"type":48,"coordinates":317},[318,319],-96.80667,32.78306,{"lat":319,"lon":318},[322],{"name":323,"role":35,"phone":10,"phoneExt":10,"email":324},"Brett Johnson, MD","Brett.Johnson@UTSouthwestern.edu",{"facility":326,"status":41,"city":327,"state":314,"zip":328,"country":45,"countryCode":46,"cosmosGeoPoint":329,"geoPoint":333,"contacts":334},"The University of Texas M.D. Anderson Cancer Center","Houston","77030",{"type":48,"coordinates":330},[331,332],-95.36327,29.76328,{"lat":332,"lon":331},[335],{"name":336,"role":35,"phone":10,"phoneExt":10,"email":337},"Mehrad Adibi, MD","MAdibi@mdanderson.org",{"type":339,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100506479","utract-jelmyto-registry-a-registry-of-patients-with-upper-tract-urothelial-cancer-utuc-treated-with-jelmyto-100506479",false,"NCT05874921","uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto","uTRACT Jelmyto Registry: A Multicenter, Prospective and Retrospective Registry to Evaluate Real World Experience and Outcomes of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto","uTRACT","Inclusion Criteria:\n\n* Adults \\>18 years old and capable of giving informed consent.\n* Diagnosis of UTUC.\n* Receipt of at least 1 dose of JELMYTO after FDA approval (15 Apr 2020).\n\nExclusion Criteria:\n\n* Incapable of giving informed consent (e.g., incarcerated individuals, individuals with dementia).\n* Receipt of 1 or more doses of JELMYTO (also referred to as UGN-101 or Mitogel in clinical development) before FDA approval (on or before 15 Apr 2020).\n* Pregnancy or lactation.\n* Unable to comply with protocol requirements (for prospective data capture).\n* Any medical or mental condition(s) that makes participation in the Registry inadvisable in the opinion of the Investigator (for prospective data capture).","ALL","18 Years",{"count":351,"type":352},400,"ESTIMATED","3 Years","OBSERVATIONAL","The purpose of this registry is to evaluate real world experience and outcomes of patients with Upper Tract Urothelial Cancer (UTUC) treated with Jelmyto in the United States.",[357,358,359,360,361,362,363,364],"Urothelial Carcinoma","Urothelial Carcinoma Recurrent","Urothelial Carcinoma Ureter","Urothelial Carcinoma Ureter Recurrent","Urothelial Cancer of Renal Pelvis","Urothelial Carcinoma of the Renal Pelvis and Ureter","Carcinoma, Transitional Cell","Transitional Cell Carcinoma of Renal Pelvis",[366,367,21,368,369,370,371,372,373,374,375,376,377,378,379,380,381,382,383,384,385,386,387,388,389,390],"Upper Tract Urothelial Cancer","UTUC","Mitomycin C","TCC","Ureteral","Upper Tract","Carcinoma","Kidney","Renal","Gel","Local","Prolonged Release","Slow Release","Kidney Sparing","Recurrence","Neoplasms by Histologic Type","Neoplasms","Urologic Neoplasms","Urogenital Neoplasms","Neoplasms by Site","Antibiotics, Antineoplastic","Antineoplastic Agents","Alkylating Agents","Nucleic Acid Synthesis Inhibitors","Enzyme Inhibitors","2025-02-25",{"date":393,"type":394},"2025-02-28","ACTUAL",{"date":396,"type":394},"2023-11-17",{"date":398,"type":352},"2028-01",{"name":5,"class":6},22]