[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100488483":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":43,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Hadassah Medical Organization","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Controls",null,"Healthy women without HPV in their cervical and vaginal sample",{"label":13,"type":10,"description":14,"interventionNames":10},"Women with HPV","Women with HPV, with or without cervical intraepithelial neoplasia or carcinoma",[16],{"name":17,"affiliation":5,"role":18},"Ahinoam Lev Sagie, MD","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","+972-54-4327178","levsagie@netvision.net.il",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Lilah Tsaitlin Mor, MD","+972-54-7753434","lilah.tsaitlin@gmail.com",[29],{"facility":30,"status":31,"city":32,"state":10,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Hadassah Medical Center","RECRUITING","Jerusalem","Israel","IL",{"type":36,"coordinates":37},"Point",[38,39],35.21633,31.76904,{"lat":39,"lon":38},[42],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},{"type":18,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ahinoam Lev-Sagie","Professor","100488483","vaginal-microbiome-and-hpv-pre-malignant-and-cervical-dysplasia-100488483",false,"NCT05640700","Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia","Assessing Personalized Vaginal Microbiome Contributions to HPV-driven Pre-malignant and Malignant Cervical Cancer","Inclusion Criteria:\n\n* Age 25-70\n* Attended the clinic for a Pap smear or colposcopy\n\nExclusion Criteria:\n\n* Patient does not approve sample collection\n* Usage of antibiotics in the month prior to clinic visit\n* Usage of any vaginal preparation or medication in the week prior to sample collection (anti-fungal, spermicides, lubricant etc.)\n* Menstruation\n* Pregnancy",true,"FEMALE","25 Years","70 Years",{"count":58,"type":59},90,"ESTIMATED","OBSERVATIONAL","In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.",[63,64,65,66],"Human Papilloma Virus","Vaginal Flora Imbalance","Cancer Cervix Uterus","Cervical Dysplasia","2025-03-15",{"date":69,"type":70},"2025-03-19","ACTUAL",{"date":72,"type":70},"2022-11-09",{"date":74,"type":59},"2025-12-30",{"name":5,"class":6},1]