[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580649":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":43,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":69,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"cesarean section group",null,"This observational study will enroll 160 women undergoing cesarean section. Participants will provide vaginal swab samples for culture, both pre-operatively and post-operatively. They will be monitored post-operatively for the development of wound infections, with wound assessments performed according to standard clinical practice. Demographic and clinical data, including antibiotic use, gestational age, and comorbidities, will be collected to assess the relationship between vaginal microbiota and post-cesarean wound infections.",[13],"Diagnostic Test: Vaginal swab and culture",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Vaginal swab and culture","Participants will undergo vaginal swab collection both pre-operatively, immediately prior to the cesarean section, and post-operatively, within a defined timeframe after the procedure. The swabs will be collected using sterile swabs, following standardized procedures to ensure accurate sampling of the vaginal microbiota. The collected samples will then be sent to a designated laboratory for culture and analysis. This process will identify and characterize the bacterial composition of the vaginal microbiota, allowing researchers to investigate potential correlations between specific microbial profiles and the development of post-cesarean section wound infections",[9],[21],{"name":22,"affiliation":5,"role":23},"Muhamed Alhagrasy","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Muhamed Alhagrasy, M.D.","CONTACT","01017313413","MuhamedAhmed.216@azhar.edu.eg",[31],{"facility":32,"status":10,"city":33,"state":10,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":10},"Al-Hussein University Hospital","Cairo","11633","Egypt","EG",{"type":38,"coordinates":39},"Point",[40,41],31.24967,30.06263,{"lat":41,"lon":40},{"type":23,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy","lecturer and consultant at Obstetrics and Gynecology Department.","100580649","vaginal-microbiota-and-post-cesarean-ssi-100580649",false,"NCT06840041","Vaginal Microbiota and Post-cesarean SSI","The Relationship Between Vaginal Microbiota and Post-Cesarean Section Wound Infection","Inclusion Criteria:\n\n* Pregnant women undergoing elective or emergency cesarean section (CS).\n* Singleton pregnancy.\n* Cesarean section performed at ≥ 37 weeks of gestation.\n\nExclusion Criteria:\n\n* Use of antibiotics within two weeks prior to delivery.\n* Known immunodeficiency.\n* Chronic infections.\n* Ruptured membranes for more than 18 hours.",true,"FEMALE","18 Years","40 Years",{"count":58,"type":59},160,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the relationship between vaginal microbiota composition and the development of post-cesarean section wound infection in women undergoing cesarean delivery. The main question it aims to answer is:\n\nIs there a correlation between specific vaginal microbiota profiles and the incidence of post-cesarean section wound infection? Can specific bacterial taxa or diversity indices within the vaginal microbiota predict the risk of post-cesarean section wound infection?\n\nParticipants will:\n\nProvide vaginal swab samples pre-operatively and post-operatively. Undergo standard post-cesarean section care and follow-up. Have wound assessment performed per standard of care, and have data collected regarding wound infection status.\n\nHave demographic and clinical data collected, including but not limited to, antibiotic use, gestational age, and comorbidities.",[63,64],"Site Infection","Cesarean Section; Complications, Wound, Infection (Following Delivery)",[66,67,68],"cesarean section","SSI","vaginal microbiota","NOT_YET_RECRUITING","2025-06-13",{"date":72,"type":73},"2025-06-15","ACTUAL",{"date":75,"type":59},"2025-06-30",{"date":77,"type":59},"2026-07-30",{"name":5,"class":6},1]