[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637450":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":20,"collaborators":24,"id":27,"slug":28,"hasResults":29,"nctId":30,"briefTitle":31,"officialTitle":32,"acronym":10,"eligibilityCriteria":33,"healthyVolunteers":29,"sex":34,"minAge":35,"maxAge":10,"enrollmentInfo":36,"targetDuration":10,"studyType":39,"phases":10,"briefSummary":40,"conditions":41,"keywords":43,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":10},{"fullName":5,"class":6},"Fujian University of Traditional Chinese Medicine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cross-Sectional External Validation Cohort",null,"This is the only study population for this cross-sectional observational real-world external validation study. The cohort consists of community-dwelling older adults aged 60 years and above, who are diagnosed with Mild Cognitive Impairment (MCI) and have long-term regular Tai Chi practice. Participants will be recruited from communities in Fuzhou, China, with a planned sample size of 150 participants.\n\nThis study will conduct a single time-point cross-sectional survey on this population, with no prospective follow-up. The sole objective is to externally validate the generalizability and clinical applicability of a pre-developed machine learning prediction model (for identifying MCI populations who gain significant cognitive benefits from Tai Chi intervention and formulating individualized Tai Chi dose prescriptions) in a real-world community setting.",[13],"Behavioral: 24-form Simplified Tai Chi (Observational Behavioral Exposure)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"BEHAVIORAL","24-form Simplified Tai Chi (Observational Behavioral Exposure)","This is the core observational exposure factor of this cross-sectional real-world external validation study, NOT an intervention actively assigned, implemented or manipulated by the investigator. This study only observes and records the existing long-term regular Tai Chi practice behavior (including dose, frequency and duration) of enrolled older adults with Mild Cognitive Impairment (MCI) during a single time-point cross-sectional survey, for the sole purpose of externally validating the generalizability of a pre-developed machine learning prediction model for Tai Chi cognitive benefit population identification and individualized dose prescription. No active behavioral intervention will be administered to any participant in this study.",[9],{"type":21,"investigatorFullName":22,"investigatorTitle":23,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Lidian Chen","Professor",[25],{"name":26,"class":6},"Peking University Third Hospital","100637450","validation-of-population-characteristics-and-dosage-prescriptions-for-cognitive-function-intervention-benefits-of-different-doses-of-tai-chi-in-elderly-patients-with-mild-cognitive-impairment-a-real-world-cross-sectional-study-100637450",false,"NCT07608510","Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study","Real-World External Validation Study on Beneficiary Population Characteristics and Individualized Dose Prescription for Cognitive Improvement of Tai Chi Intervention in Elderly Patients With Mild Cognitive Impairment","Inclusion Criteria:\n\n* 1\\. Presence of mild cognitive impairment, not demented; 2. Age ≥ 60 years old; 3.Regular practice of standardized 24-form simplified Tai Chi for at least 6 months (consistent with the form used in the parent randomized controlled trials \\[RCTs\\]) ; 4.Informed consent and voluntary participation.\n\nExclusion Criteria:\n\n1. Geriatric Depression Scale score ≥ 9 points\n2. Cognitive impairment caused by other reasons, taking drugs, poisoning, etc;\n3. Suffer from severe musculoskeletal system diseases and other contraindications to exercise and are not suitable for Tai Chi training, such as those who suffer from stroke, Parkinson's disease, and have a history of lower limb arthritis, hip and knee joint replacement, etc;\n4. Patients with severe heart, liver, kidney failure, malignant tumors, and other major diseases;\n5. Individuals with visual\u002Fauditory impairments, writing\u002Freading impairments, illiteracy, etc. that affect training and evaluation;\n6. Individuals with uncontrolled hypertension (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg after medication);\n7. Participating in other experiments that influence this study. -","ALL","60 Years",{"count":37,"type":38},150,"ESTIMATED","OBSERVATIONAL","This is a companion real-world external validation study of two pre-registered parent randomized controlled trials (RCTs, protocol IDs: FujianUTCM-1 and FujianUTCM-2). We aim to validate the generalizability and clinical applicability of a pre-developed machine learning prediction model (for Tai Chi intervention cognitive benefit population characteristics and individualized dose prescription) in a real-world community-dwelling population.",[42],"Mild Cognitive Impairment (MCI)",[44,45,46,47,48],"mild cognitive impairment","taiji","machine learning","External Validation","Real-World Study","NOT_YET_RECRUITING","2026-05-24",{"date":52,"type":53},"2026-05-27","ACTUAL",{"date":55,"type":38},"2026-05-15",{"date":57,"type":38},"2027-03-31",{"name":22,"class":6}]