[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100462078":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":62,"collaborators":66,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":27,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":30,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":30,"overallStatus":47,"whyStopped":30,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Coimbra","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"REMINDER program online","EXPERIMENTAL","The REMINDER program in this arm will be delivered by videoconferencing. It will integrate 20 sessions (with approximate length of 45-60 min), therapist-mediated, carried out twice a week, over a period of 12 weeks. Psychoeducation sessions and part of the reminiscence and memory strategies training sessions will be facilitated in groups, as means to promote social support and modeling, and the remaining will be individual sessions. Several activities aimed to promote personal development and definition and achievement of meaningful goals will be included in the program, and the program will be manualized to facilitate its future dissemination and implementation",[13],"Behavioral: REMINDER",{"label":15,"type":10,"description":16,"interventionNames":17},"REMINDER program face-to-face","The REMINDER program in this arm will be delivered face to face. It will integrate 20 sessions (with approximate length of 45-60 min), therapist-mediated, carried out twice a week, over a period of 12 weeks. Psychoeducation sessions and part of the reminiscence and memory strategies training sessions will be facilitated in groups, as means to promote social support and modeling, and the remaining will be individual sessions. Several activities aimed to promote personal development and definition and achievement of meaningful goals will be included in the program, and the program will be manualized to facilitate its future dissemination and implementation",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Brain psychoeducation program","SHAM_COMPARATOR","The control condition will have the same length as the experimental harms, including 20 psychoeducation sessions, with information regarding dementia modifiable risk factors, information on healthy lifestyles, and brain health promotion.",[23],"Behavioral: Brain health Psychoeducation",[25,31],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","REMINDER","The REMINDER program is a therapist-mediated manualized neuropsychological intervention, involving training skills to stimulate cognitive reserve, socialization and personal development, to diminish the risk of cognitive decline.",[15,9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Brain health Psychoeducation","Delivery of psychoeducation sessions about dementia modifiable risk factors, brain health solutions and lifestyle change tips.",[19],[36,41],{"name":37,"role":38,"phone":39,"phoneExt":30,"email":40},"Ana Rita Silva, PhD","CONTACT","+351962779695","anaritaess@fpce.uc.pt",{"name":5,"role":38,"phone":42,"phoneExt":30,"email":43},"+351 239851450","cineicc@fpce.uc.pt",[45],{"facility":46,"status":47,"city":48,"state":30,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Faculty of Psychology and Educational Sciences","RECRUITING","Coimbra","3002-115","Portugal","PT",{"type":53,"coordinates":54},"Point",[55,56],-8.41996,40.20686,{"lat":56,"lon":55},[59],{"name":60,"role":38,"phone":61,"phoneExt":30,"email":43},"FPCEUC","00351239 851 450",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Ana Rita Silva","Principal Investigator",[67],{"name":68,"class":6},"Fundação para a Ciência e a Tecnologia","100462078","validation-of-the-reminder-dementia-risk-reduction-program-100462078",false,"NCT05296980","Validation of the REMINDER Dementia Risk Reduction Program","Validation of a Multidomain Neuropsychological Intervention for Individuals at Risk of Dementia: the REMINDER Program","Inclusion Criteria:\n\n* Age 60 or older\n* CAIDE dementia risk score \\>8\n* Cognitive function: absence of significant cognitive impairment as per the Addenbrooke's Cognitive Examination-REVISED\n* Free of physical disabilities that preclude participation in the study\n* Willing to complete all study-related activities for 12 weeks\n\nExclusion Criteria:\n\n* Mild cognitive impairment or dementia;\n* Presence of any neurological event in their medical history that could compromise actual cognition.\n* Presence of any severe psychiatric disorder (mild depressive and anxiety symptoms meet inclusion criteria).\n* Unability to travel to the site where the sessions will be delivered (if so randomization will be circumscribed between the experimental harm REMINDER online and the control group.\n* Illiteracy",true,"ALL","60 Years","75 Years",{"count":81,"type":82},400,"ESTIMATED","INTERVENTIONAL",[85],"NA","Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies. While some RCTs have been developed in cognitive training interventions, comparative studies of merged interventions (cognitive, social and behavioral stimulation) with adequate control groups are absent, diminishing the professionals' trust on the adoption of these interventions for supporting patients. As such, the present proposal will develop a validation trial testing a multicomponent neuropsychological intervention (REMINDER), based on personal development, cognitive compensatory aids, meaningful goals setting, and behavior change techniques. The investigators will analyze its short\u002Flong-term gains and AD conversion rates. By aiming to provide a good validation study for REMINDER, the investigators will examine neurobiological, neurocognitive and functional outcomes of this intervention in comparison with an active control group (psychoeducation) in order to foster an effective outcome assessment of an intervention for individuals at risk of AD.",[88,89,90],"Healthy Aging","Risk Reduction","Old Age; Dementia","2024-05-07",{"date":93,"type":94},"2024-05-08","ACTUAL",{"date":96,"type":94},"2022-04-01",{"date":98,"type":82},"2026-10",{"name":5,"class":6},1]