[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629876":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":35,"collaborators":11,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":45,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":11,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":70,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":11},{"fullName":5,"class":6},"Medical University of Gdansk","OTHER",[8,14,19,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Omnivorous diet, healthy individuals","ACTIVE_COMPARATOR",null,[13],"Behavioral: Omnivorous diet",{"label":15,"type":16,"description":11,"interventionNames":17},"Vegan diet, healthy individuals","EXPERIMENTAL",[18],"Behavioral: Vegan diet",{"label":20,"type":10,"description":11,"interventionNames":21},"Omnivorous diet, asthmatic individuals",[13],{"label":23,"type":16,"description":11,"interventionNames":24},"Vegan diet, asthmatic individuals",[18],[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":11},"BEHAVIORAL","Omnivorous diet","Participants will follow an individually planned, nutritionally adequate, isocaloric omnivorous diet for 12 weeks. Diet plans will be prepared by a clinical dietitian. Adherence will be monitored 3-day food diaries, weekly remote consultations, and digital tools. Participants will receive vitamin D supplementation (2000 IU\u002Fday).",[20,9],{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":11},"Vegan diet","Participants will follow an individually planned, nutritionally adequate isocaloric vegan diet for 12 weeks. Diet plans will be prepared by a clinical dietitian. Adherence will be monitored 3-day food diaries, weekly remote consultations, and digital tools. Participants will receive vitamin D supplementation (2000 IU\u002Fday) and vitamin B12 supplementation according to standard recommendations.",[23,15],{"type":36,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100629876","vegan-diet-and-immune-inflammatory-outcomes-in-asthma-and-healthy-adults-100629876",false,"NCT07480369","Vegan Diet and Immune-Inflammatory Outcomes in Asthma and Healthy Adults","The Effect of a Vegan Diet on Inflammatory and Immune Biomarkers in Adult Patients With Asthma and in Healthy Individuals: A Randomized Controlled Trial","VEGASTHMA","Inclusion Criteria:\n\nFor all groups:\n\n* Aged 18-30 years\n* Willing to adhere to assigned dietary plan (vegan or omnivorous) for 12 weeks\n* Non-smoker for at least 5 years\n* Body mass index (BMI) between 18.5 and 24.9 kg\u002Fm2\n\nFor the asthma group:\n\n* Clinical diagnosis of mild or moderate asthma (GINA criteria), made at least 12 months before enrollment\n* Stable asthma status (no exacerbations or changes in therapy within the past 3 months)\n* No change in pharmacotherapy during the study period\n\nExclusion Criteria:\n\n* Use of systemic corticosteroids (oral or intravenous) within the past 3 months\n* Ongoing biological therapy for asthma (e.g., anti-IgE, anti-IL-5, anti-IL-4R)\n* Severe asthma as per GINA criteria\n* Recent asthma exacerbation requiring hospitalization or steroid burst (\\\u003C3 months)\n* Presence of other chronic autoimmune or inflammatory diseases\n* Pregnancy or lactation\n* Active infection or acute illness at the time of recruitment\n* Adherence to specialized exclusion diets (e.g., ketogenic, low-FODMAP)\n* History of eating disorders\n* Inability or unwillingness to participate in follow-up visits or comply with the protocol",true,"ALL","18 Years","50 Years",{"count":50,"type":51},280,"ESTIMATED","INTERVENTIONAL",[54],"NA","This randomized controlled study evaluates the effects of a balanced vegan diet compared with a balanced omnivorous diet on inflammatory and immune response markers and clinical asthma parameters in healthy adults and individuals with mild to moderate asthma, aged 18 to 50. Participants will follow assigned dietary plans for 12 weeks with dietitian support delivered via digital tools.",[57,58,59],"Asthma","Dietary Intervention","Vegan Diet",[61,62,63,64,65,66,67,68,69],"asthma","asthma control","inflammation","inflammatory markers","immune response","vegan diet","plant-based diet","randomized control trial","dietary intervention","NOT_YET_RECRUITING","2026-03-14",{"date":73,"type":74},"2026-03-18","ACTUAL",{"date":76,"type":51},"2026-03",{"date":78,"type":51},"2029-09-30",{"name":5,"class":6}]