[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636526":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":32,"centralContacts":36,"locations":42,"responsibleParty":65,"collaborators":26,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":26,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":26,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"National Taipei University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"low training volume resistance exercise","EXPERIMENTAL","Participants assigned to the low-volume resistance training group will perform one set per exercise at a load corresponding to 80% of 1RM. Each set will be terminated when movement velocity decreases by 30% from the first repetition. Rest intervals of 2-3 minutes will be provided between exercises.",[13],"Other: Resistance exercise",{"label":15,"type":10,"description":16,"interventionNames":17},"medium training volume resistance exercise","Participants assigned to the medium-volume resistance training group will perform three sets per exercise at 80% of 1RM. Each set will be terminated when movement velocity decreases by 30% relative to the first repetition. Rest intervals of 90 seconds will be provided between sets, and 2-3 minutes between exercises.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"high training volume resistance exercise","Participants assigned to the high-volume resistance training group will perform five sets per exercise at 80% of 1RM. Each set will be terminated when movement velocity decreases by 30% relative to the first repetition. Rest intervals of 90 seconds will be provided between sets, and 2-3 minutes between exercises.",[13],{"label":23,"type":24,"description":25,"interventionNames":26},"sedentary control","NO_INTERVENTION","Participants in control trial stayed sedentary during the period.",null,[28],{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"Resistance exercise","The RT program will consist of 12 sessions over a 4-week period, with participants training three times per week and at least one rest day between sessions. All sessions will be supervised by research personnel to ensure proper technique and safety. Exercises will be performed using resistance machines and will include chest press, shoulder press, seated row, lat pulldown, and leg press.",[19,9,15],[33],{"name":34,"affiliation":5,"role":35},"Shun-Hsi Tsai, Ph.D.","PRINCIPAL_INVESTIGATOR",[37],{"name":34,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","+88686741111","68523","shunhsi@mail.ntpu.edu.tw",[43],{"facility":44,"status":45,"city":46,"state":26,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"National Taiwan Normal University","RECRUITING","Taipei","116","Taiwan","TW",{"type":51,"coordinates":52},"Point",[53,54],121.52639,25.05306,{"lat":54,"lon":53},[57,61],{"name":58,"role":38,"phone":59,"phoneExt":26,"email":60},"Hung-Wen Liu, Ph.D.","+88677496863","hwliu@ntnu.edu.tw",{"name":62,"role":38,"phone":63,"phoneExt":26,"email":64},"Kuan-Tsen Yeh, M.S.","+886932815383","mickyyehyeh@gmail.com",{"type":66,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100636526","velocity-based-resistance-training-effects-on-inflammation-in-older-adults-100636526",false,"NCT07566832","Velocity-Based Resistance Training Effects on Inflammation in Older Adults","Dose-Response Effects of Velocity-Based Resistance Training on Anti-Inflammatory Responses in Older Adults","Inclusion Criteria:\n\n* Aged 60-75 years or older\n* No regular resistance training habit (defined as ≥2 sessions per week) in the past year\n* No musculoskeletal injuries within the past six months\n\nExclusion Criteria:\n\n* Obesity (BMI \\> 30 kg\u002Fm²), diabetes, hypertension, cancer, heart, kidney, or liver disease, or any other condition that may influence study outcomes.\n* Regular use of anti-inflammatory medications (e.g., NSAIDs).\n* Smoking or alcohol abuse\n* Inability to safely perform the prescribed resistance exercise movements\n* Unable to fully comprehend the study information and instructions.",true,"ALL","60 Years","75 Years",{"count":79,"type":80},60,"ESTIMATED","INTERVENTIONAL",[83],"NA","This study aims to investigate the effects of resistance training (RT) with different training volumes on immune modulation and anti-inflammatory responses in older adults. Participants will be randomly assigned to one of three RT volume groups (low, medium, or high) or a non-exercise control group. Participants in the training groups will complete a 4-week RT program, followed by a 4-week detraining phase. The findings are expected to provide evidence for volume-specific RT prescriptions to support healthy aging.",[86,87],"Aging","Inflammatory Response","2026-05-04",{"date":90,"type":91},"2026-05-08","ACTUAL",{"date":93,"type":91},"2026-04-20",{"date":95,"type":80},"2029-12",{"name":5,"class":6},1]