[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621746":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":45,"responsibleParty":60,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":9,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":25,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":88,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Benex","EXPERIMENTAL","Participants in this arm will undergo flapless vertical root extraction using the Benex system, followed immediately by implant placement with a standardized guided surgical protocol. The Benex system applies controlled vertical traction through a screw anchored in the root canal, minimizing lateral forces and reducing trauma to the socket walls. All patients will receive the same implant system, grafting material if indicated, provisional restoration, and final prosthesis according to the study protocol.",[13],"Procedure: vertical extraction",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","ACTIVE_COMPARATOR","Participants in this arm will undergo atraumatic incisal extraction using periotomes and forceps, followed immediately by implant placement with the same implant system and surgical protocol as the test group. This represents the current conventional method of atraumatic extraction. All subsequent implant placement, grafting (if needed), provisionalization, and final restoration steps will be standardized and identical to the test group.",[19],"Procedure: Conventional exctraction",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","vertical extraction",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Conventional exctraction","Tooth extraction is one of the most common procedures in dentistry, forming a cornerstone of both general dental practice and surgical specialties such as oral surgery and periodontology. Traditional extraction methods often involved the use of elevators and forceps to apply significant lateral and rotational forces, which could traumatize the alveolar bone and soft tissues. Over the past few decades, with the rise of implant dentistry and the need to preserve bone for future prosthetic rehabilitation, clinicians have shifted towards atraumatic extraction techniques. These methods aim to remove teeth while minimizing damage to surrounding hard and soft tissues, particularly the delicate alveolar socket walls.",[15],[31],{"name":32,"affiliation":33,"role":34},"Mahmoud Shalash","National Research Centre, Egypt","STUDY_DIRECTOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Mihas Ibrahim, M.Sc","CONTACT","00201008551124","mihad.ibrahim@dentistry.cu.edu.eg",{"name":42,"role":38,"phone":43,"phoneExt":25,"email":44},"Dalia Ghalwash, PhD","00201114333923","dalia.ghalwash@bue.edu.eg",[46],{"facility":5,"status":25,"city":47,"state":25,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Cairo","11865","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],31.24967,30.06263,{"lat":55,"lon":54},[58],{"name":59,"role":38,"phone":39,"phoneExt":25,"email":40},"Mihad Ibrahim, M.Sc",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Mihad Ibrahim","Dr.","100621746","vertical-root-extraction-for-immediate-implant-100621746",false,"NCT07374627","Vertical Root Extraction for Immediate Implant","Vertical Root Extraction for Immediate Implant Placement : A Prospective Clinical And Radiographic Single Arm Study.","Inclusion Criteria:\n\n\\- dults aged 18 to 55 years. Classified as ASA I-II (healthy or mild systemic condition, fit for surgery). The presence of a single hopeless maxillary anterior tooth (incisor or canine) indicated for extraction.\n\nAdequate palatal and apical bone volume to achieve primary stability for immediate implant placement.\n\nPatients are able and willing to provide informed consent and comply with study visits.\n\nExclusion Criteria:\n\nSmokers consuming more than 10 cigarettes per day. Pregnant or lactating women. Patients with systemic contraindications to surgery (e.g., chemotherapy, radiotherapy, bisphosphonate therapy).\n\nPatients with untreated periodontal disease. Presence of active local infection at the surgical site.\n\n\\-",true,"ALL","18 Years","80 Years",{"count":76,"type":77},14,"ESTIMATED","INTERVENTIONAL",[80],"NA","Immediate implant placement in the esthetic zone has become a preferred treatment modality due to its potential to shorten treatment duration, reduce surgical interventions, and preserve the natural contour of peri-implant tissues (Chen \\& Buser, 2009; Lang et al., 2012). Despite these advantages, the technique remains surgically demanding, especially in the anterior maxilla, where the labial plate is often thin and highly susceptible to post-extraction resorption (Spray et al., 2000; Chappuis et al., 2017).\n\nThe greatest dimensional changes in alveolar ridge volume occur within the first 8-12 weeks after tooth extraction, with reductions in both height and width of the buccal bone crest (Araújo \\& Lindhe, 2005; Tan et al., 2012). This remodeling compromises mucogingival architecture, often leading to mid-facial soft tissue recession and esthetic failures. Conventional extraction methods, which apply rotational or lateral forces using elevators and forceps, risk fracturing the socket walls and accelerating bone loss (Araujo \\& Lindhe, 2009; Oghli \\& Steveling, 2010).\n\nThe introduction of atraumatic extraction systems aimed to address this challenge. The Benex vertical extraction system operates by inserting a screw into the root canal and applying controlled vertical traction. This approach minimizes lateral stress on socket walls, theoretically preserving the thin labial plate, which is critical for esthetic success (Muska et al., 2013; Canellas et al., 2021). Vertical traction avoids socket expansion and microfractures, enabling safer immediate implant placement in compromised situations.\n\nCase reports and retrospective series have demonstrated encouraging clinical results with Benex, including intact labial plates on CBCT, high implant survival, and favorable Pink Esthetic Scores (Fürhauser et al., 2005; Canellas et al., 2021). Patients also report reduced discomfort and trauma perception, suggesting potential psychosocial benefits. However, most of the current evidence is based on small-scale case series (Blus \\& Szmukler-Moncler, 2010; Singla \\& Sharma, 2020), and randomized controlled trials comparing Benex-assisted extraction with conventional atraumatic extraction are lacking.\n\nA robust RCT evaluating both objective esthetic outcomes (Midfacial mucosal recession, PES, CBCT bone preservation) and subjective patient-reported outcomes (PROMs) is therefore essential to validate the clinical value of the Benex system in the esthetic zone.",[83,84],"Implant Placement in Maxillary Esthetic Zone","Immediate Dental Implant Loading",[86,87],"Dental Implant","root extraction","NOT_YET_RECRUITING","2026-01-21",{"date":91,"type":92},"2026-01-29","ACTUAL",{"date":94,"type":77},"2026-02-01",{"date":96,"type":77},"2026-04-30",{"name":5,"class":6},1]