[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626963":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":33,"locations":43,"responsibleParty":55,"collaborators":57,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":28,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":28,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":28,"overallStatus":81,"whyStopped":28,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"NYU Langone Health","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Technical Evaluation Group","EXPERIMENTAL","Participants, both sighted-blindfolded and people with blindness or low vision, will complete simple navigation, object-identification, and object-reaching tasks, both with and without VIS4ION's services.",[13],"Device: VIS4ION Platform",{"label":15,"type":10,"description":16,"interventionNames":17},"Extended Use Trial: Group A","Participants with blindness or low vision will complete navigation and object-identification tasks with the device during months 1-6, then without the device during months 6-12.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Extended Use Trial: Group B","Participants with blindness or low vision will complete navigation and object-identification tasks without the device during months 1-6, then with the device during months 6-12.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DEVICE","VIS4ION Platform","The VIS4ION platform, a non-invasive wearable and smartphone-based system providing auditory (bone-conduction headphones) and haptic (wristband\u002Fbelt) feedback to enhance mobility and daily living for people with blindness or low vision.",[15,19,9],null,[30],{"name":31,"affiliation":5,"role":32},"John-Ross Rizzo, MD","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":28,"email":38},"Mahya Beheshti","CONTACT","646-501-9189","Mahya.beheshti@nyulangone.org",{"name":40,"role":36,"phone":41,"phoneExt":28,"email":42},"Giles Hamilton-Fletcher","646-906-6008","Giles.hamilton-fletcher@nyulangone.org",[44],{"facility":5,"status":28,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":28},"New York","10016","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-74.00597,40.71427,{"lat":53,"lon":52},{"type":56,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[58],{"name":59,"class":60},"National Eye Institute (NEI)","NIH","100626963","virtual-assistance-for-daily-living-neurophysiological-and-functional-effects-in-low-vision-100626963",false,"NCT07442461","Virtual Assistance for Daily Living: Neurophysiological and Functional Effects in Low Vision","Effects of Visual Impairment on Neurophysiological Responses and the Feasibility and Impact of Multimodal Virtual Assistance for Instrumental Activities of Daily Living in Low Vision Populations","Inclusion Criteria:\n\nPeople with Visual Impairment:\n\n* Age between 18 and 80 years.\n* Diagnosis of visual impairment (any level, any etiology).\n* Current use of a primary mobility assistive device (e.g., white cane or guide dog).\n* Ability to travel independently (without assistance from another person).\n* Capacity to provide informed consent.\n* Willingness to complete all study-related assessments and procedures\n\nHealthy Controls:\n\n* Age between 18 and 80 years.\n* No self-reported visual impairment or use of mobility assistive devices.\n* Capacity to provide informed consent.\n* Willingness to complete all study-related assessments and procedures.\n\nExclusion Criteria:\n\n* Significant cognitive dysfunction (score \\\u003C24 on Folsteins' Mini Mental Status Examination)\n* Previous neurological illness, complicated medical condition (inclusive of comorbid cognitive impairment)\n* Significant mobility restrictions; people using walkers and wheelchairs\n* Pregnancy\n* Profound auditory impairments (i.e., cannot understand human speech)\n* Somatosensory impairments to the trunk or torso that precludes use of the haptic interfaces\n* Significant depression (score \\> 11 on the Geriatric Depression scale)",true,"ALL","18 Years","80 Years",{"count":73,"type":74},150,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study aims to investigate how visual impairment affects neurophysiological and biomechanical responses during real-world navigation and daily activities, with a focus on the rehabilitative feasibility and impact of assistive technologies. These technologies include applications and wearable devices designed to support various aspects of daily living for individuals with visual impairment. The VIS4ION platform (Visually Impaired Smart Service System for Spatial Intelligence \\& On-board Navigation), a wearable system providing tactile and auditory feedback, is one component of this broader study. VIS4ION is designed to enhance environmental awareness and reduce cognitive load during mobility tasks for the visually impaired.",[80],"Visual Impairment","NOT_YET_RECRUITING","2026-02-25",{"date":84,"type":85},"2026-03-02","ACTUAL",{"date":87,"type":74},"2026-03-01",{"date":89,"type":74},"2028-12-30",{"name":5,"class":6},1]