[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615338":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":25,"responsibleParty":47,"collaborators":50,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":25,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":25,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":78,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":25},{"fullName":5,"class":6},"Istanbul Aydın University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Dual Task Group","EXPERIMENTAL","Participants in the dual-task group will receive a motor-cognitive dual-task exercise program in addition to conventional physiotherapy. The program includes simultaneous motor activities (such as reaching, grasping, and upper-limb functional tasks) combined with cognitive challenges involving attention, memory, problem-solving, and decision-making. Each session lasts 60 minutes and is delivered three times per week for 12 weeks. The aim of the intervention is to enhance cortical activation, improve motor planning, and support upper-limb functional performance through combined motor and cognitive stimulation.",[13,14],"Other: Conventional Physiotherapy Program","Other: Dual Task",{"label":16,"type":10,"description":17,"interventionNames":18},"Virtual reality (VR) Group","Participants in the virtual reality (VR) group will receive a VR-based exercise program in addition to conventional physiotherapy. The VR program includes interactive upper-limb activities designed to promote active movement, motor control, and engagement through immersive, game-based tasks. Exercises target reaching, grasping, coordination, and proprioceptive awareness in a visually enriched environment. Each session lasts 60 minutes and is conducted three times per week for 12 weeks. The intervention aims to stimulate cortical activation, support motor learning, and enhance upper-limb functional performance.",[13,19],"Other: Virtual Reality",[21,26,30],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Conventional Physiotherapy Program","The conventional physiotherapy program includes educating the child and family about the condition and treatment goals, maintaining regular communication, planning sessions according to the child's abilities, motivating the child, and promoting active participation. Exercises are designed based on functional, daily-life, and play activities to maintain attention and engagement, following El-Shamy et al. (2017).\n\nBefore each session, a 15-minute warm-up of shoulder internal rotation, pectoral, and elbow extension stretches will be performed (3 sets of 10 repetitions, 5-second hold).",[9,16],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Virtual Reality","Children in the VR group will perform conventional physiotherapy followed by 20 minutes of VR-based exercises using the Becure Leap Motion system. The games involve interactive tasks designed to improve wrist, hand, and upper-limb movements, coordination, and motor control, with progressively increasing difficulty levels. Sessions are supervised by the study physiotherapist.",[16],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":25},"Dual Task","Children in the dual-task group will perform exercises integrating conventional physiotherapy with cognitive-motor dual-task activities for a total of 45 minutes per session, following Wollesen et al. (2022). Cognitive tasks will be age- and ability-appropriate: younger children will perform basic memory and attention tasks, while older children will engage in more complex problem-solving, rapid decision-making, and language-based tasks.\n\nTask selection will consider the impact on motor performance, including movement quality, divided attention, reaction time, coordination, and executive functions, aiming to maximize motor-cognitive interaction. To maintain motivation, tasks will be gamified, competitive, offer choices based on personal interest, provide feedback, and reward achievements. Task difficulty will be adjusted individually.",[9],[35],{"name":36,"affiliation":37,"role":38},"Zeynep Hoşbay","Biruni University","PRINCIPAL_INVESTIGATOR",[40,45],{"name":41,"role":42,"phone":43,"phoneExt":25,"email":44},"Barış CELBEK, Ph.D.","CONTACT","05077536669","bariscelbek3@gmail.com",{"name":46,"role":42,"phone":43,"phoneExt":25,"email":44},"CELBEK",{"type":38,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Barış CELBEK","Lecturer in Physiotherapy and Rehabilitation",[51,53],{"name":52,"class":6},"Istanbul University",{"name":37,"class":6},"100615338","virtual-reality-and-dual-task-training-for-cortical-plasticity-in-children-with-brachial-plexus-injury-100615338",false,"NCT07291310","Virtual Reality and Dual-Task Training for Cortical Plasticity in Children With Brachial Plexus Injury","Development of Cortical Plasticity Through Virtual Reality and Dual-Task Training in Children With Brachial Plexus Birth Injury: A Different Perspective in Paediatric Neurorehabilitation","Inclusion Criteria:\n\n* Children aged 7-14 years\n* Diagnosed with unilateral DBPP\n* C5-C6 or C5-C7 involvement (Narakas I, IIa, IIb)\n* Modified Pediatric Mini-Mental Scale score ≥26\n* Child and parent willing to participate in the study\n\nExclusion Criteria:\n\n* Previous nerve surgery for DBPP\n* Surgery within the past year or Botulinum Toxin injection within the past 3 months\n* Any neurological condition other than DBPP\n* Vision or hearing impairments affecting participation\n* Contraindications for fMRI\n* Fixed contractures in shoulder, elbow, wrist, or finger joints\n* Participation in regular physiotherapy or other rehabilitation programs within the past 3 months","ALL","7 Years","14 Years",{"count":65,"type":66},14,"ESTIMATED","INTERVENTIONAL",[69],"NA","Brachial plexus birth injury (BPBI) is a condition that occurs when the nerves controlling the arm are injured during birth, leading to weakness, limited movement, and sensory problems. These motor difficulties may also affect cognitive processes related to movement. BPBI requires long-term follow-up and rehabilitation.\n\nThis study will compare two treatment approaches in children with BPBI:\n\n* virtual reality (VR)-based exercises, and\n* motor-cognitive dual-task exercises. We will examine their effects on brain adaptation (cortical activation), muscle strength, joint motion, proprioception, and upper-limb function. Fourteen children aged 7-14 years will be randomly assigned to one of the two programs, each delivered for 12 weeks. Afterward, participants will continue a 9-month home program. Assessments will be conducted at baseline, after treatment, and at 12 months, including functional MRI (fMRI).\n\nThis study will be the first to evaluate long-term brain changes and functional outcomes after these two rehabilitation approaches in children with BPBI.",[72,73],"Brachial Plexus Birth Palsy","Physical Therapy",[75,76,77,27,31],"Brachial Plexus","Physiotherapy","Cortical Plasticity","NOT_YET_RECRUITING","2025-12-18",{"date":81,"type":82},"2025-12-24","ACTUAL",{"date":84,"type":66},"2026-01-01",{"date":86,"type":66},"2029-01-01",{"name":5,"class":6}]