[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530234":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":37,"centralContacts":42,"locations":48,"responsibleParty":65,"collaborators":36,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":36,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":36,"enrollmentInfo":77,"targetDuration":36,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":36,"overallStatus":51,"whyStopped":36,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Immersive Virtual Reality","EXPERIMENTAL","Patient with sickle cell disease experiencing acute vaso-occlusive crisis randomized to this arm will participate in an active immersive application on the virtual reality headset with hand-held controllers. The active immersive application will allow the user to interact directly with the application and move through the virtual environment .The patient will be able to use the active immersive application on the device for a maximum of two hours.",[13],"Device: Virtual Reality Headset and Hand-Held Controllers",{"label":15,"type":10,"description":16,"interventionNames":17},"Passive Immersive Virtual Reality","Patient with sickle cell disease experiencing acute vaso-occlusive crisis randomized to this arm will participate in a passive immersive application on the virtual reality headset with hand-held controllers. The passive immersive application will not allow the user to interact directly with the application or move through the virtual environment .The patient will be able to use the passive immersive application on the device for a maximum of two hours.",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Blindfold and Ear Plugs","PLACEBO_COMPARATOR","Patient with sickle cell disease experiencing acute vaso-occlusive crisis randomized to this arm will wear a blindfold and ear plugs. The patient will be able to remain blindfolded and earplugs for a maximum of two hours.",[23],"Other: Blindfolding and Noise Cancelling",[25,32],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","Virtual Reality Headset and Hand-Held Controllers","Study Group-Virtual reality headset and hand-held controllers will be used as an adjuvant to pain management care.",[9,15],[31],"Meta Quest 2",{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"Blindfolding and Noise Cancelling","Control group-Blindfold and noise cancelling headphones will be a placebo comparator group to the experimental interventions of virtual reality devices.",[19],null,[38],{"name":39,"affiliation":40,"role":41},"R. Gentry Wilklerson, MD","U of Maryland, Baltimore","PRINCIPAL_INVESTIGATOR",[43],{"name":44,"role":45,"phone":46,"phoneExt":36,"email":47},"R. Gentry Wilkerson, MD","CONTACT","410-328-4237","gwilkerson@som.umaryland.edu",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"University of Maryland Medical Systems","RECRUITING","Baltimore","Maryland","21201","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-76.61219,39.29038,{"lat":61,"lon":60},[64],{"name":44,"role":45,"phone":46,"phoneExt":36,"email":47},{"type":41,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"Richard Gentry Wilkerson","Associate Professor","100530234","virtual-reality-devices-as-an-adjunct-to-usual-care-for-patients-with-sickle-cell-disease-experiencing-vaso-occlusive-crises-100530234",false,"NCT06184126","Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises","Pilot Study to Investigate the Use of Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises","Inclusion Criteria:\n\n* Adult (age \\> 18 years) emergency department patient\n* History of sickle cell disease\n* Presenting to the emergency department due to acute pain related to sickle cell disease thought to be due to vaso-occlusive crisis\n\nExclusion Criteria:\n\n* Prior enrollment in this study\n* Presenting with a chief complaint suggestive of a complicated crisis (such as concern for acute chest syndrome, splenic sequestration, hepatic sequestration, pulmonary embolism) as determined by the clinical care provider\n* Not being treated with intravenous opioids for the vaso-occlusive crisis\n* Patients who lack the capacity to provide informed consent\n* Medical history of seizures or known intolerance to virtual reality\n* Disabilities like vision and hearing defects etc. that preclude the use of a head mounted virtual reality device.\n* Known to be pregnant\n* Incarcerated at the time of evaluation\n* Over the age of 89 years old","ALL","18 Years",{"count":78,"type":79},30,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study aims to evaluate the use of virtual reality as an adjunct to standard care for patients with sickle cell disease experiencing vaso-occlusive crises.",[85,86,87],"Sickle Cell Disease","Vaso-occlusive Pain Episode in Sickle Cell Disease","Acute Pain","2025-12-17",{"date":90,"type":91},"2025-12-24","ACTUAL",{"date":93,"type":91},"2024-11-01",{"date":95,"type":79},"2026-12-31",{"name":5,"class":6},1]