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for therapy\n* Beneficiary of the French social security system\n* Give an informed consent to participate\n* Willing to comply with all study procedures and duration\n\nExclusion Criteria:\n\n* Visual disturbance making impossible the use of virtual reality equipment (e.g. advanced retinal degeneration, central scotoma, age-related macular degeneration)\n* Pregnant woman\n* Minor or adult under guardianship, conservatorship, under judicial protection, persons deprived of their liberty\n* Balance disorder (e.g. cerebellar disorder, inner ear disorder)\n* Photosensitive epilepsy\n* Refusal to participate","ALL","18 Years",{"count":177,"type":178},124,"ESTIMATED","INTERVENTIONAL",[181],"NA","Gambling disorder (GD) is recognized as an addictive disorder in the DSM-5. Craving is a core phenomenon in addiction that can lead to relapse in problem gambling for pathological gamblers. Exposure Therapy (ET) focuses on craving in addiction treatment. ET in Cognitive-Behavioral Therapy (CBT) is based on classical conditioning that addresses the association between contextual cues and the craving response. ET helps the patient to reduce craving when faced with cues triggering craving. ET includes in vivo exposure and imaginal exposure. The literature recommends being as close as possible to the context of addiction to facilitate the extinction of craving but in vivo ET is complicated to perform. For GD, in outpatient consultation, bringing a patient to a casino presents obstacles (e.g., time, human and financial cost, agreement with casino for therapy).\n\nThe study will be to assess the effectiveness of Virtual Reality Exposure Therapy (VRET) in a virtual gambling environment. Various trials show that VRET is no more or less effective than classical ET in CBT but has other advantages for motivation to treatment. This research aims to compare efficacy between CBT with VRET and CBT with imaginal exposure for treatment of GD in a multicenter, randomized, controlled, non-inferiority clinical trial.",[184],"Gambling Disorder",[186,187,188,189,190],"Exposure therapy","virtual reality","cognitive behavioral therapy","pathological gambling","CBT","2026-05-11",{"date":193,"type":194},"2026-05-14","ACTUAL",{"date":196,"type":194},"2023-07-12",{"date":198,"type":178},"2027-07",{"name":5,"class":6},10]