[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611788":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":41,"centralContacts":49,"locations":58,"responsibleParty":78,"collaborators":31,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":82,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":31,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":102,"overallStatus":61,"whyStopped":31,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"National Institute of Mental Health, Czech Republic","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Virtual reality exposure","EXPERIMENTAL","Participants complete 6-week CBT program with five 30-40-minute sessions of exposure administered via a virtual reality headset (once a week). The intervention involves exposure to various symptom provoking scenarios in the virtual house environment - \"OCD house\". Scenarios can be adjusted to distinct OCD dimensions: contamination\u002Fcleaning, fear-of-harm\u002Fchecking, symmetry\u002Fordering. Stimuli can be also freely combined across dimensions, so that the scenarios fit to individual needs.",[13],"Behavioral: Exposure Therapy (Virtual Reality)",{"label":15,"type":16,"description":17,"interventionNames":18},"Cognitive flexibility training","ACTIVE_COMPARATOR","Control group attends 6-week CBT program with five sessions of 30-40 minutes of cognitive training via virtual reality headset using \"VRcity\" cognitive training games.",[19],"Behavioral: Cognitive flexibility training",{"label":21,"type":16,"description":22,"interventionNames":23},"Standard CBT without additional VR treatment","Control group completes the standard 6-week CBT program only, with no VR sessions.",[24],"Behavioral: Standard CBT program without VR interventions",[26,32,35],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"BEHAVIORAL","Exposure Therapy (Virtual Reality)","Virtual reality scenarios consists of exposures to OCD symptom provoking stimuli and response prevention (e.g. having dirty hands without washing them immediately) with the support of the therapist. The goal of VRET is sufficient reduction in anxiety and acceleration of progress in classical CBT.",[9],null,{"type":27,"name":15,"description":33,"armGroupLabels":34,"otherNames":31},"Participants play series of various cognitive games previously developed in NIMH aimed at cognitive flexibility. Games are presented using immersive VR (HTC vive headset). The set includes for instance Go\u002FNo-go paradigm with a shooting range addressing inhibitory control, Flies - hit a fly game addressing set-shifting and Castle game addressing spatial memory and reversal learning.",[15],{"type":27,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"Standard CBT program without VR interventions","Standart CBT program (performed in all groups). The program involves regular group and individual psychotherapy sessions 5 days per 6 weeks.",[21],[40],"Cognitive Behavior Therapy",[42,46],{"name":43,"affiliation":44,"role":45},"Iveta Fajnerová, Ph.D.","National Institute of Mental Health (NIMH)","STUDY_DIRECTOR",{"name":47,"affiliation":44,"role":48},"Pavla Stopková, Ph.D.","PRINCIPAL_INVESTIGATOR",[50,55],{"name":51,"role":52,"phone":53,"phoneExt":31,"email":54},"Iveta Fajnerová","CONTACT","+420-608501034","Iveta.fajnerova@nudz.cz",{"name":56,"role":52,"phone":31,"phoneExt":31,"email":57},"Pavla Stopková","Pavla.stopkova@nudz.cz",[59],{"facility":60,"status":61,"city":62,"state":31,"zip":31,"country":63,"countryCode":31,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"National Institute of Mental Health","RECRUITING","Klecany","Czechia",{"type":65,"coordinates":66},"Point",[67,68],14.41148,50.17599,{"lat":68,"lon":67},[71,75],{"name":72,"role":52,"phone":73,"phoneExt":31,"email":74},"Martina Janíková","+420775594595","martina.janikova@nudz.cz",{"name":51,"role":52,"phone":76,"phoneExt":31,"email":77},"+420608501034","iveta.fajnerova@nudz.cz",{"type":48,"investigatorFullName":51,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Supervisor","100611788","virtual-reality-exposure-therapy-for-obsessive-compulsive-disorder-a-randomized-controlled-trial-in-inpatients-100611788",false,"NCT07245134","Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients","Virtual Reality Exposure Therapy in Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients","OCD-VRET1","Inclusion Criteria:\n\n* Diagnosis of OCD (F42) using currently valid DSM-V and ICD-11\n* Fluent in Czech\n\nExclusion Criteria:\n\n* Any other psychiatric, neurological and serious somatic illness\n* Substance abuse\n* Psychotropic medication (e.g. benzodiazepines) except antidepressants, antipsychotic medication and hypnotics.\n* Contradictions to using a virtual reality (e.g., epilepsy, balance problems)\n* Pregnancy\n* Cardiostimulator and mental implants","ALL","17 Years","55 Years",{"count":92,"type":93},62,"ESTIMATED","INTERVENTIONAL",[96],"NA","The aim of this study is to evaluate the efficacy of virtual reality exposure therapy (VRET) as a treatment for obsessive-compulsive disorder (OCD). Participants are randomly assigned to one of the following interventions: a) exposure condition - the group with a standard CBT program enriched with exposure therapy in VR (VRET), b) control condition 1 - the group with a standard CBT program enriched with VR cognitive training aimed at cognitive flexibility or c) control condition 2 - standard CBT program without any additional VR intervention. The treatment effect will be evaluated using pre\u002Fpost assessments, as well as monitoring adherence to exposure and response prevention assignments.",[99,100,101,40],"Obsessive-Compulsive Disorder","Virtual Reality Exposure Therapy","Virtual Reality Cognitive Training",[103,104,105,106],"obsessive-compulsive disorder","VR exposure therapy","cognitive flexibility","Inpatient clinic","2025-11-20",{"date":109,"type":110},"2025-11-24","ACTUAL",{"date":112,"type":110},"2022-11-15",{"date":114,"type":93},"2026-12-30",{"name":5,"class":6},1]