[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608795":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":34,"locations":43,"responsibleParty":63,"collaborators":21,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":21,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":46,"whyStopped":21,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"National Institute of Mental Health, Czech Republic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Within-subject comparison of a waiting list condition with exposure therapy in VR","EXPERIMENTAL","Patients first complete informed consent and baseline questionnaires and are placed on a waiting list for five weeks. After this period, they are reassigned to the active group, which receives five sessions of exposure therapy in virtual reality over a subsequent five-week period. The treatment effect will be evaluated using pre\u002Fpost assessments, as well as monitoring adherence to exposure and response prevention assignments.",[13,14],"Behavioral: exposure therapy in virtual reality","Other: Wait list",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"BEHAVIORAL","exposure therapy in virtual reality","Participants complete five 30-40-minute sessions of exposure therapy administered via a virtual reality headset once a week. The exposure involves exposure to various symptom-provoking scenarios in the virtual house environment. Scenarios can be adjusted to distinct OCD dimensions: contamination\u002Fcleaning, fear-of-harm\u002Fchecking symmetry\u002Fordering, and also to symptoms of hoarding. Stimuli can be also freely combined across different dimensions, so that the scenarios fit the individual needs.",[9],null,{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Wait list","The patients are assigned to a waitlist period for 5 weeks. During this period they are not allowed to change any treatment (phramacotherapy and\u002For psychoterapy as usual) started prior to the trial.",[9],[27,31],{"name":28,"affiliation":29,"role":30},"Iveta Hocko Fajnerová, Ph.D.","National Institute of Mental Health (NIMH)","STUDY_DIRECTOR",{"name":32,"affiliation":29,"role":33},"Pavla Stopková, Ph.D.","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":21,"email":39},"Iveta Hocko Fajnerová","CONTACT","+420608501034","iveta.fajnerova@nudz.cz",{"name":41,"role":37,"phone":21,"phoneExt":21,"email":42},"Pavla Stopková","pavla.stopkova@nudz.cz",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":21,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Nationa Institute of Mental Health","RECRUITING","Klecany","Česká Republika","250 67","Czechia",{"type":52,"coordinates":53},"Point",[54,55],14.41148,50.17599,{"lat":55,"lon":54},[58,62],{"name":59,"role":37,"phone":60,"phoneExt":21,"email":61},"Martina Janíková","+420775594595","martina.janikova@nudz.cz",{"name":36,"role":37,"phone":38,"phoneExt":21,"email":39},{"type":33,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Iveta Fajnerová","Supervisor","100608795","virtual-reality-exposure-therapy-for-obsessive-compulsive-disorder-outpatients-trial-100608795",false,"NCT07206199","Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: Outpatients Trial","Virtual Reality Exposure Therapy in Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Outpatients","OCD-VRET2","Inclusion Criteria:\n\n* Diagnosis of OCD (F42) using currently valid DSM-V and ICD-11\n* Fluent in Czech\n\nExclusion Criteria:\n\n* Any other psychiatric, neurological and serious somatic illness\n* Substance abuse\n* Psychotropic medication (e.g. benzodiazepines) except antidepressants, antipsychotic medication and hypnotics.\n* Contradictions to using a virtual reality (e.g., epilepsy, balance problems)\n* Pregnancy\n* Cardiostimulator and mental implants","ALL","18 Years","55 Years",{"count":78,"type":79},30,"ESTIMATED","INTERVENTIONAL",[82],"NA","The aim of this study is to evaluate the efficacy of virtual reality exposure therapy (VRET) as a treatment for obsessive-compulsive disorder (OCD). This study focuses on patients receiving treatment in outpatient psychiatry or clinical psychology settings, utilizing a within-subject design for comparison. Patients first complete informed consent and baseline questionnaires and are placed on a waiting list for five weeks. After this period, they are reassigned to the active (experimental) group, which will receive five sessions of exposure therapy in virtual reality over a subsequent five-week period. The treatment effect will be evaluated using pre\u002Fpost assessments, as well as monitoring adherence to exposure and response prevention assignments.",[85],"Obsessive-compulsive Disorder",[87,88,89,90,91],"Obsessive-compulsive disorder","virtual reality","Virtual reality exposure therapy","within-subject design","Outpatients","2025-09-25",{"date":94,"type":95},"2025-10-03","ACTUAL",{"date":97,"type":95},"2024-03-20",{"date":99,"type":79},"2027-03-31",{"name":5,"class":6},1]